| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603912 |
|
| Stage: |
TS12 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 7.5-8.0 |
| Image: |
4B |
|
| Specimen Label: |
4B |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603913 |
| Pattern: |
Ubiquitous |
| Stage: |
TS13 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 8.5 |
| Image: |
2B E8.5 |
| Note: |
Expression in whole body including neuroepithelium. |
| Specimen Label: |
2B E8.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603915 |
| Pattern: |
Ubiquitous |
| Stage: |
TS15 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 9.5 |
| Image: |
2B E9.5 |
| Note: |
Expression in whole body including neuroepithelium. |
| Specimen Label: |
2B E9.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
| Pattern: |
Ubiquitous |
| Stage: |
TS17 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 10.5 |
| Image: |
2B E10.5 |
| Note: |
Expression in whole body including neuroepithelium. |
| Specimen Label: |
2B E10.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640815 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 9.5 |
| Image: |
2B E9.5 |
|
| Specimen Label: |
2B E9.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640817 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 10.5 |
| Image: |
2B E10.5 |
|
| Specimen Label: |
2B E10.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185817 |
| Pattern: |
Ubiquitous |
| Stage: |
TS17 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 10.5 |
| Image: |
2D |
| Note: |
Ubiquitous expression in cranial area including the brain. |
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185820 |
| Pattern: |
Ubiquitous |
| Stage: |
TS20 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 12.5 |
| Image: |
2E |
| Note: |
Ubiquitous expression in cranial regions. |
| Specimen Label: |
2E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1607313 |
| Pattern: |
Not Specified |
| Stage: |
TS13 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 8.5 |
| Image: |
2B E8.5 |
|
| Specimen Label: |
2B E8.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1607315 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 9.5 |
| Image: |
2B E9.5 |
|
| Specimen Label: |
2B E9.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1718520 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 12.5 |
| Image: |
2E |
|
| Specimen Label: |
2E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1664016 |
|
| Stage: |
TS16 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 10.0 |
| Image: |
4C |
|
| Specimen Label: |
4C |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1664016 |
|
| Stage: |
TS16 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 10.0 |
| Image: |
4D |
|
| Specimen Label: |
4D |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1659515 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 9.5 |
| Image: |
2B E9.5 |
|
| Specimen Label: |
2B E9.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1612917 |
| Pattern: |
Ubiquitous |
| Stage: |
TS17 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 10.5 |
| Image: |
2G |
| Note: |
Ubiquitous expression in neural crest cells and non-Dlx5-expressing mesodermal cells. |
| Specimen Label: |
2G |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1646917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 10.5 |
| Image: |
2B E10.5 |
|
| Specimen Label: |
2B E10.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2513323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 15.5 |
| Image: |
2F |
| Note: |
Relatively higher expression in masticatory muscles |
| Specimen Label: |
2F |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3617444 |
| Age: |
postnatal day 0 |
| Image: |
P0 |
| Note: |
Authors indicate that there was either ubiquitous or background expression. |
| Specimen Label: |
P0 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754027 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3617444 |
| Age: |
postnatal day 0 |
| Image: |
P0 |
|
| Specimen Label: |
P0 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280927 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3617444 |
| Age: |
postnatal day 0 |
| Image: |
P0 |
|
| Specimen Label: |
P0 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267921 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3617444 |
| Age: |
embryonic day 13.5 |
| Image: |
E13.5 |
|
| Specimen Label: |
E13.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Very strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267923 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 15.5 |
| Image: |
2I |
|
| Specimen Label: |
2I |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668822 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 14.0 |
| Image: |
4H fourth |
|
| Specimen Label: |
4H fourth |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757721 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3617444 |
| Age: |
embryonic day 13.5 |
| Image: |
E13.5 |
| Note: |
Authors indicate that there was either ubiquitous or background expression. |
| Specimen Label: |
E13.5 |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3615961 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-03-23 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3617444 |
| Age: |
postnatal day 0 |
| Image: |
P0 |
| Note: |
Authors indicate that there was either ubiquitous or background expression. |
| Specimen Label: |
P0 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618418 |
| Pattern: |
Not Specified |
| Stage: |
TS18 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 11.0 |
| Image: |
4E |
|
| Specimen Label: |
4E |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618416 |
| Pattern: |
Not Specified |
| Stage: |
TS16 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 10.0 |
| Image: |
4C |
|
| Specimen Label: |
4C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618416 |
| Pattern: |
Not Specified |
| Stage: |
TS16 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 10.0 |
| Image: |
4D |
|
| Specimen Label: |
4D |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618418 |
| Pattern: |
Not Specified |
| Stage: |
TS18 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 11.0 |
| Image: |
4F |
|
| Specimen Label: |
4F |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6431551 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-06-04 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6431571 |
| Age: |
embryonic day 15.5 |
| Image: |
2I |
| Note: |
Intense expression in brain particularly in the ventricular zone. |
| Specimen Label: |
2I |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 11.5 |
| Image: |
4H first |
|
| Specimen Label: |
4H first |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 12.5 |
| Image: |
4H second |
|
| Specimen Label: |
4H second |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 13.5 |
| Image: |
4H third |
|
| Specimen Label: |
4H third |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:707852 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274822 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3587889 |
| Age: |
embryonic day 14.0 |
| Image: |
4H fourth |
|
| Specimen Label: |
4H fourth |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruiz-Lozano P |
| Year: |
1997 |
| Journal: |
Dev Dyn |
| Title: |
Developmental expression of the murine spliceosome-associated protein mSAP49. |
| Volume: |
208 |
| Issue: |
4 |
| Pages: |
482-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng S |
| Year: |
2013 |
| Journal: |
Genome Res |
| Title: |
A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. |
| Volume: |
23 |
| Issue: |
6 |
| Pages: |
998-1007 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Isono K |
| Year: |
2005 |
| Journal: |
Genes Dev |
| Title: |
Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. |
| Volume: |
19 |
| Issue: |
5 |
| Pages: |
536-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKee AE |
| Year: |
2005 |
| Journal: |
BMC Dev Biol |
| Title: |
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. |
| Volume: |
5 |
|
| Pages: |
14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
MGC Data curation in Mouse Genome Informatics |
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| Publication |
| First Author: |
University of California, Davis |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the University of California, Davis |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Mouse Synonym Curation |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
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| Title: |
Data Curation Using Mouse Genome Assembly |
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| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
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| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
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| Title: |
Nomenclature Committee Use |
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•
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| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
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| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
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| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
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| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
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| Title: |
Annotation inferences using phylogenetic trees |
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•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| Publication |
| First Author: |
Petit F |
| Year: |
2014 |
| Journal: |
Clin Genet |
| Title: |
Nager syndrome: confirmation of SF3B4 haploinsufficiency as the major cause. |
| Volume: |
86 |
| Issue: |
3 |
| Pages: |
246-51 |
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| DO Term |
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| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the RNA recognition motif 1 (RRM1) of SF3B4, also termed pre-mRNA-splicing factor SF3b 49kDa (SF3b50), or spliceosome-associated protein 49 (SAP 49). SF3B4 is a component of the multiprotein complex splicing factor 3b (SF3B), an integral part of the U2 small nuclear ribonucleoprotein (snRNP) and the U11/U12 di-snRNP. SF3B is essential for the accurate excision of introns from pre-messenger RNA, and is involved in the recognition of the pre-mRNA's branch site within the major and minor spliceosomes []. SF3B4 functions to tether U2 snRNP with pre-mRNA at the branch site during spliceosome assembly []. It is an evolutionarily highly conserved protein with orthologues across diverse species.SF3B4 contains two closely adjacent N-terminal RNA recognition motifs (RRMs). It binds directly to pre-mRNA and also interacts directly and highly specifically with another SF3B subunit called SAP 145 [].Mutations in the SF3B4 gene cause Nager syndrome, a form of acrofacial dysostosis which affects the development of the face, hands, and arms []. |
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| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the RNA recognition motif 2 (RRM2) of SF3B4, also termed pre-mRNA-splicing factor SF3b 49kDa (SF3b50), or spliceosome-associated protein 49 (SAP 49). SF3B4 is a component of the multiprotein complex splicing factor 3b (SF3B), an integral part of the U2 small nuclear ribonucleoprotein (snRNP) and the U11/U12 di-snRNP. SF3B is essential for the accurate excision of introns from pre-messenger RNA, and is involved in the recognition of the pre-mRNA's branch site within the major and minor spliceosomes []. SF3B4 functions to tether U2 snRNP with pre-mRNA at the branch site during spliceosome assembly []. It is an evolutionarily highly conserved protein with orthologues across diverse species.SF3B4 contains two closely adjacent N-terminal RNA recognition motifs (RRMs). It binds directly to pre-mRNA and also interacts directly and highly specifically with another SF3B subunit called SAP 145 [].Mutations in the SF3B4 gene cause Nager syndrome, a form of acrofacial dysostosis which affects the development of the face, hands, and arms []. |
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| Publication |
| First Author: |
Champion-Arnaud P |
| Year: |
1994 |
| Journal: |
Genes Dev |
| Title: |
The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. |
| Volume: |
8 |
| Issue: |
16 |
| Pages: |
1974-83 |
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•
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| Publication |
| First Author: |
Golas MM |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Molecular architecture of the multiprotein splicing factor SF3b. |
| Volume: |
300 |
| Issue: |
5621 |
| Pages: |
980-4 |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
424
 |
| Fragment?: |
false |
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| Publication |
| First Author: |
Kumar S |
| Year: |
2024 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Etiology of craniofacial and cardiac malformations in a mouse model of SF3B4-related syndromes. |
| Volume: |
121 |
| Issue: |
39 |
| Pages: |
e2405523121 |
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