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Search results 101 to 172 out of 172 for Sh3pxd2b

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0.028s
Type Details Score
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_22
Specimen Label: euxassay_014164_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_23
Specimen Label: euxassay_014164_23
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1736223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_13
Specimen Label: euxassay_014164_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3262324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4441309
Age: embryonic day 16.5
Note: Expression in the long bones of the upper limb.
Specimen Label: S2F
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1790622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4441309
Age: embryonic day 14.5
Specimen Label: S2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:4441309
Age: embryonic day 18.5
Specimen Label: S2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_09
Specimen Label: euxassay_014164_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_10
Specimen Label: euxassay_014164_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_16
Specimen Label: euxassay_014164_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_17
Specimen Label: euxassay_014164_17
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:4845387
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1618417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848964
Age: embryonic day 10.5
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1834222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4441309
Age: embryonic day 14.5
Specimen Label: S2E
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_05
Specimen Label: euxassay_014164_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_06
Specimen Label: euxassay_014164_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_07
Specimen Label: euxassay_014164_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_08
Specimen Label: euxassay_014164_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_09
Specimen Label: euxassay_014164_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_10
Specimen Label: euxassay_014164_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_11
Specimen Label: euxassay_014164_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_12
Specimen Label: euxassay_014164_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_15
Specimen Label: euxassay_014164_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_16
Specimen Label: euxassay_014164_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_17
Specimen Label: euxassay_014164_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_18
Specimen Label: euxassay_014164_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_19
Specimen Label: euxassay_014164_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4426260
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828043
Age: embryonic day 14.5
Image: euxassay_014164_20
Specimen Label: euxassay_014164_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4441309
Age: embryonic day 16.5
Note: Expression in the developing facial and skull bones.
Specimen Label: S2G
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4441306
Assay Type: RNA in situ
Annotation Date: 2010-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4441309
Age: embryonic day 16.5
Note: Expression in the developing facial and skull bones.
Specimen Label: S2H
Detected: true
Specimen Num: 8
Publication
First Author: Mehes E
Year: 2019
Journal: Sci Rep
Title: Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4.
Volume: 9
Issue: 1
Pages: 14363
Publication
First Author: Cejudo-Martin P
Year: 2014
Journal: PLoS One
Title: Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5.
Volume: 9
Issue: 9
Pages: e107674
Publication
First Author: Palmer K
Year: 2016
Journal: Dev Biol
Title: Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Volume: 415
Issue: 2
Pages: 216-227
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
DO Term
Protein Domain
Type: Domain
Description: This entry represents the first SH3 domain of SH3PXD2B.SH3 and PX domain-containing protein 2B (SH3PXD2B, also known as Fad49 or Tks4) is an adaptor protein required for functional podosome formation []. It binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides []. It regulates epidermal growth factor-dependent cell migration []and has been linked to cancer []. Mutations in the SH3PXD2B gene cause Frank-ter Haar syndrome, a rare disease characterised by abnormalities that affect bone, heart, and eye development []. It contains an N-terminal Phox homology (PX) domain and four SH3 domains.
Protein Domain
Type: Domain
Description: This entry represents the second SH3 domain of SH3PXD2B.SH3 and PX domain-containing protein 2B (SH3PXD2B, also known as Fad49 or Tks4) is an adaptor protein required for functional podosome formation []. It binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides []. It regulates epidermal growth factor-dependent cell migration []and has been linked to cancer []. Mutations in the SH3PXD2B gene cause Frank-ter Haar syndrome, a rare disease characterised by abnormalities that affect bone, heart, and eye development []. It contains an N-terminal Phox homology (PX) domain and four SH3 domains.
Protein Domain
Type: Domain
Description: This entry represents the third SH3 domain of SH3PXD2B.SH3 and PX domain-containing protein 2B (SH3PXD2B, also known as Fad49 or Tks4) is an adaptor protein required for functional podosome formation []. It binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides []. It regulates epidermal growth factor-dependent cell migration []and has been linked to cancer []. Mutations in the SH3PXD2B gene cause Frank-ter Haar syndrome, a rare disease characterised by abnormalities that affect bone, heart, and eye development []. It contains an N-terminal Phox homology (PX) domain and four SH3 domains.
Protein Domain
Type: Domain
Description: This entry represents the fourth SH3 domain of SH3PXD2B.SH3 and PX domain-containing protein 2B (SH3PXD2B, also known as Fad49 or Tks4) is an adaptor protein required for functional podosome formation []. It binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides []. It regulates epidermal growth factor-dependent cell migration []and has been linked to cancer []. Mutations in the SH3PXD2B gene cause Frank-ter Haar syndrome, a rare disease characterised by abnormalities that affect bone, heart, and eye development []. It contains an N-terminal Phox homology (PX) domain and four SH3 domains.
Protein Domain
Type: Domain
Description: This entry represents the PX domain of SH3PXD2A and SH3PXD2B. The PX domain is involved in targeting of proteins to phosphoinositide-enriched membranes, and may also be involved in protein-protein interaction [].SH3PXD2A, also known as Fish or Tks5, is a scaffold protein with five SH3 domains and one PX domain. It is required for podosome formation, for degradation of the extracellular matrix, and for invasion of some cancer cells [, ]. SH3PXD2A binding partners include ADAM-family metalloproteases []and Nck adaptor proteins [].SH3 and PX domain-containing protein 2B (SH3PXD2B, also known as Fad49 or Tks4) is an adaptor protein required for functional podosome formation []. It binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides []. It regulates epidermal growth factor-dependent cell migration []and has been linked to cancer []. Mutations in the SH3PXD2B gene cause Frank-ter Haar syndrome, a rare disease characterised by abnormalities that affect bone, heart, and eye development []. It contains an N-terminal Phox homology (PX) domain and four SH3 domains.
Publication
First Author: Blouw B
Year: 2015
Journal: PLoS One
Title: The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo.
Volume: 10
Issue: 3
Pages: e0121003
Publication
First Author: Abram CL
Year: 2003
Journal: J Biol Chem
Title: The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.
Volume: 278
Issue: 19
Pages: 16844-51
Publication
First Author: Stylli SS
Year: 2009
Journal: J Cell Sci
Title: Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.
Volume: 122
Issue: Pt 15
Pages: 2727-40
Publication
First Author: Bravo J
Year: 2001
Journal: Mol Cell
Title: The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate.
Volume: 8
Issue: 4
Pages: 829-39
Publication
First Author: Seals DF
Year: 2005
Journal: Cancer Cell
Title: The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells.
Volume: 7
Issue: 2
Pages: 155-65
Protein
Organism: Mus musculus/domesticus
Length: 1124  
Fragment?: false