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Search results 101 to 187 out of 187 for Sh3rf1

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0.024s
Type Details Score
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12764
Specimen Label: GUDMAP:12764
Detected: false
Specimen Num: 4
GXD Expression
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754021
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3508505
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3508505
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:6504
Specimen Label: GUDMAP:6504
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12764
Specimen Label: GUDMAP:12764
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3508505
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2776227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5540018
Age: postnatal day 0
Image: GUDMAP:7236
Specimen Label: GUDMAP:7236
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3508505
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3508505
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:6504
Specimen Label: GUDMAP:6504
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12764
Specimen Label: GUDMAP:12764
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:6504
Specimen Label: GUDMAP:6504
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3508505
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3508505
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:6504
Specimen Label: GUDMAP:6504
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12764
Specimen Label: GUDMAP:12764
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:6504
Specimen Label: GUDMAP:6504
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507061
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5540018
Age: embryonic day 15.5
Image: GUDMAP:12763
Specimen Label: GUDMAP:12763
Detected: false
Specimen Num: 3
Protein
Organism: Mus musculus/domesticus
Length: 836  
Fragment?: false
Publication
First Author: West RJH
Year: 2018
Journal: Hum Mol Genet
Title: The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia.
Volume: 27
Issue: 8
Pages: 1382-1395
Publication
First Author: Yao M
Year: 2022
Journal: Cell Rep
Title: POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function.
Volume: 39
Issue: 1
Pages: 110642
Publication
First Author: Figueroa C
Year: 2003
Journal: Oncogene
Title: Akt negatively regulates translation of the ternary complex factor Elk-1.
Volume: 22
Issue: 36
Pages: 5554-61
Publication
First Author: Zhang F
Year: 2016
Journal: J Biol Chem
Title: A Novel c-Jun N-terminal Kinase (JNK) Signaling Complex Involved in Neuronal Migration during Brain Development.
Volume: 291
Issue: 22
Pages: 11466-75
Publication  
First Author: Goodwani S
Year: 2020
Journal: Int J Mol Sci
Title: Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions.
Volume: 21
Issue: 14
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 892  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 828  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 862  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase SH3RF1
Type: chain
End: 892
Publication
First Author: Kukekov NV
Year: 2006
Journal: J Biol Chem
Title: Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.
Volume: 281
Issue: 22
Pages: 15517-24
Publication
First Author: Xu Z
Year: 2003
Journal: EMBO J
Title: POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.
Volume: 22
Issue: 2
Pages: 252-61
Publication
First Author: Tuvia S
Year: 2007
Journal: J Cell Biol
Title: The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp.
Volume: 177
Issue: 1
Pages: 51-61
Protein Domain
Type: Domain
Description: SH3RF1 (or POSH) and SH3RF3 (or POSH2) are scaffold proteins that function as E3 ubiquitin-protein ligases. They contain an N-terminal RING finger domain and four SH3 domains []. This entry represents the fourth SH3 domain, located at the C terminus of SH3RF1 and SH3RF3, and similar domains. SH3RF1 plays a role in calcium homeostasis through the control of the ubiquitin domain protein Herp []. It may also have a role in regulating death receptor mediated and JNK mediated apoptosis []. SH3RF3 interacts with p21-activated kinase 2 (PAK2) and GTP-loaded Rac1 [].
Protein Domain
Type: Family
Description: SH3RF1 (or POSH) is a scaffold protein that function as an E3 ubiquitin-protein ligase. It contains an N-terminal RING finger domain and four SH3 domains. It belongs to the POSH family, which includes POSH1, POSH2 and POSH3 [].
Protein Domain
Type: Family
Description: SH3RF2 is also called POSHER (POSH-eliminating RING protein) or HEPP1 (heart protein phosphatase 1-binding protein). It acts as an anti-apoptotic regulator of the JNK pathway by binding to and promoting the degradation of SH3RF1 (or POSH), a scaffold protein that is required for pro-apoptotic JNK activation []. It may also play a role in cardiac functions together with protein phosphatase 1 []. SH3RF2 contains an N-terminal RING finger domain and three SH3 domains.
Protein Domain
Type: Domain
Description: SH3RF2 is also called POSHER (POSH-eliminating RING protein) or HEPP1 (heart protein phosphatase 1-binding protein). It acts as an anti-apoptotic regulator of the JNK pathway by binding to and promoting the degradation of SH3RF1 (or POSH), a scaffold protein that is required for pro-apoptotic JNK activation []. It may also play a role in cardiac functions together with protein phosphatase 1 []. SH3RF2 contains an N-terminal RING finger domain and three SH3 domains. This entry represents the second SH3 domain of SH3RF2.
Publication
First Author: Wilhelm M
Year: 2012
Journal: J Biol Chem
Title: Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein.
Volume: 287
Issue: 3
Pages: 2247-56
Publication
First Author: Chen CY
Year: 2010
Journal: Biochem Biophys Res Commun
Title: FLJ23654 encodes a heart protein phosphatase 1-binding protein (Hepp1).
Volume: 391
Issue: 1
Pages: 698-702
Publication
First Author: Kärkkäinen S
Year: 2010
Journal: FEBS Lett
Title: POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain.
Volume: 584
Issue: 18
Pages: 3867-72
Protein Domain
Type: Domain
Description: SH3RF2 is also called POSHER (POSH-eliminating RING protein) or HEPP1 (heart protein phosphatase 1-binding protein). It acts as an anti-apoptotic regulator of the JNK pathway by binding to and promoting the degradation of SH3RF1 (or POSH), a scaffold protein that is required for pro-apoptotic JNK activation []. It may also play a role in cardiac functions together with protein phosphatase 1 []. SH3RF2 contains an N-terminal RING finger domain and three SH3 domains. This entry represents the first SH3 domain, located at the N-terminal half, of SH3RF2.
Protein
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: false
Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112