Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_14 |
|
Specimen Label: |
euxassay_008435_14 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_15 |
|
Specimen Label: |
euxassay_008435_15 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_16 |
|
Specimen Label: |
euxassay_008435_16 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_17 |
|
Specimen Label: |
euxassay_008435_17 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_01 |
|
Specimen Label: |
euxassay_008435_01 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_02 |
|
Specimen Label: |
euxassay_008435_02 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_03 |
|
Specimen Label: |
euxassay_008435_03 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_04 |
|
Specimen Label: |
euxassay_008435_04 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_05 |
|
Specimen Label: |
euxassay_008435_05 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_06 |
|
Specimen Label: |
euxassay_008435_06 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_07 |
|
Specimen Label: |
euxassay_008435_07 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_08 |
|
Specimen Label: |
euxassay_008435_08 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_09 |
|
Specimen Label: |
euxassay_008435_09 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_10 |
|
Specimen Label: |
euxassay_008435_10 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_11 |
|
Specimen Label: |
euxassay_008435_11 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_12 |
|
Specimen Label: |
euxassay_008435_12 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_13 |
|
Specimen Label: |
euxassay_008435_13 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_14 |
|
Specimen Label: |
euxassay_008435_14 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_15 |
|
Specimen Label: |
euxassay_008435_15 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_16 |
|
Specimen Label: |
euxassay_008435_16 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_17 |
|
Specimen Label: |
euxassay_008435_17 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_18 |
|
Specimen Label: |
euxassay_008435_18 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_19 |
|
Specimen Label: |
euxassay_008435_19 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_20 |
|
Specimen Label: |
euxassay_008435_20 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_21 |
|
Specimen Label: |
euxassay_008435_21 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2360971 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828046 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008435_22 |
|
Specimen Label: |
euxassay_008435_22 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
Publication |
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The Jackson Laboratory |
Year: |
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Alleles produced for the KOMP project by The Jackson Laboratory |
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Mouse Genome Informatics Scientific Curators |
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Helmholtz Zentrum Muenchen GmbH |
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MGI Direct Data Submission |
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Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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UniProt Feature |
Begin: |
1 |
Description: |
E3 ubiquitin-protein ligase SH3RF3 |
Type: |
chain |
End: |
878 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
617
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
344
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
438
 |
Fragment?: |
false |
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Publication |
First Author: |
Kukekov NV |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. |
Volume: |
281 |
Issue: |
22 |
Pages: |
15517-24 |
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Publication |
First Author: |
Tuvia S |
Year: |
2007 |
Journal: |
J Cell Biol |
Title: |
The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp. |
Volume: |
177 |
Issue: |
1 |
Pages: |
51-61 |
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Publication |
First Author: |
Wilhelm M |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. |
Volume: |
282 |
Issue: |
2 |
Pages: |
1288-95 |
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Protein Domain |
Type: |
Domain |
Description: |
SH3RF1 (or POSH) and SH3RF3 (or POSH2) are scaffold proteins that function as E3 ubiquitin-protein ligases. They contain an N-terminal RING finger domain and four SH3 domains []. This entry represents the fourth SH3 domain, located at the C terminus of SH3RF1 and SH3RF3, and similar domains. SH3RF1 plays a role in calcium homeostasis through the control of the ubiquitin domain protein Herp []. It may also have a role in regulating death receptor mediated and JNK mediated apoptosis []. SH3RF3 interacts with p21-activated kinase 2 (PAK2) and GTP-loaded Rac1 []. |
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Publication |
First Author: |
Wilhelm M |
Year: |
2007 |
Journal: |
Dev Neurosci |
Title: |
Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. |
Volume: |
29 |
Issue: |
4-5 |
Pages: |
355-62 |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the third SH3 domain, located in the middle, of SH3RF3.SH3RF3 (also known as POSH2) is a scaffold protein with E3 ubiquitin-protein ligase activity []. It was identified in the screen for interacting partners of p21-activated kinase 2 (PAK2). It may play a role in regulating JNK mediated apoptosis in certain conditions []. It also interacts with GTP-loaded Rac1 []. SH3RF3 is highly homologous to SH3RF1; it also contains an N-terminal RING finger domain and four SH3 domains. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
892
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
891
 |
Fragment?: |
false |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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