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Search results 101 to 130 out of 130 for Shoc2

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Type Details Score
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31182717 | J:280819
First Author: Jones GG
Year: 2019
Journal: Nat Commun
Title: SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.
Volume: 10
Issue: 1
Pages: 2532
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Publication
31577942 | J:300779
First Author: Sulahian R
Year: 2019
Journal: Cell Rep
Title: Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Volume: 29
Issue: 1
Pages: 118-134.e8
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Gene
102548992 | Shoc2-ps1
Type: gene
Organism: rat
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Gene
108695695 | shoc2.L
Type: gene
Organism: frog, African clawed
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Gene
380042 | shoc2.S
Type: gene
Organism: frog, African clawed
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DO Term
DOID:0080692 | Noonan syndrome-like disorder with loose anagen hair 1
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Allele
Shoc2<tm1.1Mhan> | MGI:4459449
Name: Shoc2, leucine rich repeat scaffold protein; targeted mutation 1.1, Min Han
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
24711380 | J:208862
First Author: Rachmin I
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Erbin is a negative modulator of cardiac hypertrophy.
Volume: 111
Issue: 16
Pages: 5902-7
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Genotype
Genotype
Symbol: Shoc2/Shoc2
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
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Publication
10878805 | J:63225
First Author: Borg JP
Year: 2000
Journal: Nat Cell Biol
Title: ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor.
Volume: 2
Issue: 7
Pages: 407-14
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Publication
26056141 | J:227321
First Author: Xie CM
Year: 2015
Journal: J Cell Biol
Title: Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Volume: 209
Issue: 5
Pages: 721-37
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Protein Domain
IPR032927 | Erbin
Type: Family
Description: Erbin (also known as Protein LAP2), was first identified as an adaptor for the receptor ERBB2/HER2 in epithelia []. It is involved in inhibition of several intracellular signalling pathways, such as Ras-mediated activation of extracellular signal-regulated kinase (ERK), nuclear factor kappaB, and transforming growth factor beta signalling pathways [].It contains an N-terminal domain with 16 leucine-rich repeats and a C-terminal PDZ domain. Through its amino-terminal region, Erbin disrupts Ras-Raf interaction by preventing the Ras-binding protein Shoc2 from binding to Ras, and thus acting as a tumour suppressor [].
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Genotype
Genotype
Symbol: Shoc2/Shoc2 Tg(Tek-cre)#Xya/?
Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6 * Kunming
Zygosity: cn
Has Mutant Allele: true
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Protein
Q80TH2
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
B2RUJ2
Organism: Mus musculus/domesticus
Length: 1294  
Fragment?: false
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Protein
B7ZNX6
Organism: Mus musculus/domesticus
Length: 1411  
Fragment?: false
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Protein
B7ZNY4
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
B2RUK2
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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