Type |
Details |
Score |
Publication |
First Author: |
Gui T |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling. |
Volume: |
377 |
Issue: |
2 |
Pages: |
415-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deneault E |
Year: |
2009 |
Journal: |
Cell |
Title: |
A functional screen to identify novel effectors of hematopoietic stem cell activity. |
Volume: |
137 |
Issue: |
2 |
Pages: |
369-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hung YS |
Year: |
2024 |
Journal: |
Commun Biol |
Title: |
Protogenin facilitates trunk-to-tail HOX code transition via modulating GDF11/SMAD2 signaling in mammalian embryos. |
Volume: |
7 |
Issue: |
1 |
Pages: |
1669 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bachmanov AA |
Year: |
2001 |
Journal: |
Chem Senses |
Title: |
Positional cloning of the mouse saccharin preference (Sac) locus. |
Volume: |
26 |
Issue: |
7 |
Pages: |
925-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma J |
Year: |
2019 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. |
Volume: |
60 |
Issue: |
2 |
Pages: |
661-676 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Ski oncogene |
Type: |
chain |
End: |
725 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
964
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
925
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1008
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Ski family transcriptional corepressor 1 (SKOR1), also known as ladybird homeobox corepressor 1 or fussel-15 homologue, belongs to Ski family. Like the other members, it is characterised by a Ski homologue domain and a SAND domain - a domain found in some nuclear proteins involved in chromatin-dependent transcriptional regulation. Fussel-15 is mainly expressed in the central nervous system (CNS). The Ski family of nuclear oncoproteins is known to repress transforming growth factor-beta (TGF-beta) signalling through inhibition of transcriptional activity of Smad proteins. Fussel-15 interacts with Smad1, Smad2 and Smad3 molecules and suppresses mainly BMP signalling pathway, but it has only minor effects on TGF-beta signalling []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2019 |
Journal: |
Mol Immunol |
Title: |
SKI and SMAD4 are essential for IL-21-induced Th17 differentiation. |
Volume: |
114 |
|
Pages: |
260-268 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruusgaard JC |
Year: |
2005 |
Journal: |
Acta Physiol Scand |
Title: |
Muscle hypertrophy induced by the Ski protein: cyto-architecture and ultrastructure. |
Volume: |
185 |
Issue: |
2 |
Pages: |
141-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Ski family of nuclear oncoproteins represses transforming growth factor-beta (TGF-beta) signaling through inhibition of transcriptional activity of Smad proteins. This entry represents Ski family transcriptional corepressor 2 (also known as Fussel-18), which acts as a TGF-beta antagonist. Its expression is restricted to the nervous system []. |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
SKI family transcriptional corepressor 1 |
Type: |
chain |
End: |
964 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
SKI family transcriptional corepressor 2 |
Type: |
chain |
End: |
1008 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1236
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Minaki Y |
Year: |
2008 |
Journal: |
Gene Expr Patterns |
Title: |
Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker. |
Volume: |
8 |
Issue: |
6 |
Pages: |
418-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li P |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
SKI Expression Suppresses Pathogenic Th17 Cell Response and Mitigates Experimental Autoimmune Encephalomyelitis. |
Volume: |
12 |
|
Pages: |
707899 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Overbeek PA |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct Data Submission 2011/12/27 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hammond KL |
Year: |
1998 |
Journal: |
Mech Dev |
Title: |
Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb. |
Volume: |
74 |
Issue: |
1-2 |
Pages: |
121-31 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Sutrave P |
Year: |
1990 |
Journal: |
Genes Dev |
Title: |
ski can cause selective growth of skeletal muscle in transgenic mice. |
Volume: |
4 |
Issue: |
9 |
Pages: |
1462-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
936
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; targeted mutation 1.1, Richard A Cohen |
Allele Type: |
Targeted |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Publication |
First Author: |
Prathapam T |
Year: |
2001 |
Journal: |
Nucleic Acids Res |
Title: |
Ski interacts with the evolutionarily conserved SNW domain of Skip. |
Volume: |
29 |
Issue: |
17 |
Pages: |
3469-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizuhara E |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1. |
Volume: |
280 |
Issue: |
5 |
Pages: |
3645-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deheuninck J |
Year: |
2009 |
Journal: |
Cell Res |
Title: |
Ski and SnoN, potent negative regulators of TGF-beta signaling. |
Volume: |
19 |
Issue: |
1 |
Pages: |
47-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo K |
Year: |
2004 |
Journal: |
Curr Opin Genet Dev |
Title: |
Ski and SnoN: negative regulators of TGF-beta signaling. |
Volume: |
14 |
Issue: |
1 |
Pages: |
65-70 |
|
•
•
•
•
•
|
Allele |
Name: |
SKI family transcriptional corepressor 1; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
SKI family transcriptional corepressor 2; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Halbach F |
Year: |
2013 |
Journal: |
Cell |
Title: |
The yeast ski complex: crystal structure and RNA channeling to the exosome complex. |
Volume: |
154 |
Issue: |
4 |
Pages: |
814-26 |
|
•
•
•
•
•
|
Allele |
Name: |
PR domain containing 16; cleft secondary palate 1 |
Allele Type: |
Chemically induced (ENU) |
Attribute String: |
Hypomorph |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion. |
|
•
•
•
•
•
|