| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1716828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal adult |
| Image: |
Adult |
|
| Specimen Label: |
Adult |
| Detected: |
false |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 6-7 |
|
|
| Specimen Label: |
P6/7 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 8-10 |
| Image: |
P8/10 |
|
| Specimen Label: |
P8/10 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1647028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 6 |
|
|
| Specimen Label: |
CNS |
| Detected: |
false |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603924 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:3585958 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression was widespread. |
| Specimen Label: |
Embryo |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915726 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:3585958 |
| Age: |
embryonic day 18.0 |
|
| Note: |
Expression was detected in the vitreal outer neuroblastic layer. |
| Specimen Label: |
E18 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 0-1 |
| Image: |
P0/1 |
| Note: |
Expression was detected in the outer neuroblastic layer. |
| Specimen Label: |
P0/1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 2-3 |
| Image: |
P2/3 |
| Note: |
Expression was detected in the outer neuroblastic layer. |
| Specimen Label: |
P2/3 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 6-7 |
|
|
| Specimen Label: |
P6/7 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3585958 |
| Age: |
postnatal day 8-10 |
| Image: |
P8/10 |
|
| Specimen Label: |
P8/10 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3585060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1859224 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:3585958 |
| Age: |
embryonic day 16.0 |
| Image: |
E16 |
| Note: |
Expression was detected in the vitreal outer neuroblastic layer. |
| Specimen Label: |
E16 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4947536 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360354 |
| Pattern: |
Not Specified |
| Stage: |
TS04 |
| Assay Id: |
MGI:4947545 |
| Age: |
embryonic day 3.5 |
|
| Note: |
There is general expression in all cells. |
| Specimen Label: |
3A blastocyst |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4947536 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160403 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:4947545 |
| Age: |
embryonic day 3.0 |
|
| Note: |
There is general expression in all cells. |
| Specimen Label: |
3A morula |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kotake Y |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation. |
| Volume: |
280 |
| Issue: |
2 |
| Pages: |
1095-102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhong L |
| Year: |
2007 |
| Journal: |
J Clin Invest |
| Title: |
Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells. |
| Volume: |
117 |
| Issue: |
10 |
| Pages: |
2869-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Umanskaya K |
| Year: |
2007 |
| Journal: |
Mol Cell Biol |
| Title: |
Skp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptor. |
| Volume: |
27 |
| Issue: |
21 |
| Pages: |
7615-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maddika S |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity. |
| Volume: |
29 |
| Issue: |
5 |
| Pages: |
1235-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao B |
| Year: |
2019 |
| Journal: |
Nat Immunol |
| Title: |
Notch and the pre-TCR coordinate thymocyte proliferation by induction of the SCF subunits Fbxl1 and Fbxl12. |
| Volume: |
20 |
| Issue: |
10 |
| Pages: |
1381-1392 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Piva R |
| Year: |
2002 |
| Journal: |
Mol Cell Biol |
| Title: |
In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. |
| Volume: |
22 |
| Issue: |
23 |
| Pages: |
8375-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hatakeyama S |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. |
| Volume: |
96 |
| Issue: |
7 |
| Pages: |
3859-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maruyama S |
| Year: |
2001 |
| Journal: |
Genomics |
| Title: |
Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10. |
| Volume: |
78 |
| Issue: |
3 |
| Pages: |
214-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wesselkamper SC |
| Year: |
2006 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
The role of metallothionein in the pathogenesis of acute lung injury. |
| Volume: |
34 |
| Issue: |
1 |
| Pages: |
73-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu Z |
| Year: |
2013 |
| Journal: |
EMBO J |
| Title: |
pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location. |
| Volume: |
32 |
| Issue: |
6 |
| Pages: |
844-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li M |
| Year: |
2008 |
| Journal: |
Nat Cell Biol |
| Title: |
The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. |
| Volume: |
10 |
| Issue: |
9 |
| Pages: |
1083-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Q |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity. |
| Volume: |
110 |
| Issue: |
3 |
| Pages: |
978-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang Z |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination. |
| Volume: |
24 |
| Issue: |
20 |
| Pages: |
8951-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chander H |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4. |
| Volume: |
6 |
| Issue: |
8 |
| Pages: |
e22456 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shin HJ |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. |
| Volume: |
534 |
| Issue: |
7608 |
| Pages: |
553-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cinelli P |
| Year: |
2008 |
| Journal: |
BMC Dev Biol |
| Title: |
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. |
| Volume: |
8 |
|
| Pages: |
57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Golson ML |
| Year: |
2015 |
| Journal: |
Diabetes |
| Title: |
Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion. |
| Volume: |
64 |
| Issue: |
11 |
| Pages: |
3829-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saiga T |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development. |
| Volume: |
29 |
| Issue: |
13 |
| Pages: |
3529-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miranda-Carboni GA |
| Year: |
2008 |
| Journal: |
Genes Dev |
| Title: |
A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. |
| Volume: |
22 |
| Issue: |
22 |
| Pages: |
3121-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kosaka Y |
| Year: |
2012 |
| Journal: |
Mol Cell Biol |
| Title: |
14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle. |
| Volume: |
32 |
| Issue: |
24 |
| Pages: |
5089-102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramakrishna S |
| Year: |
2007 |
| Journal: |
Dev Dyn |
| Title: |
Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor. |
| Volume: |
236 |
| Issue: |
4 |
| Pages: |
1000-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Simonson L |
| Year: |
2020 |
| Journal: |
Dev Biol |
| Title: |
Keratin 13 deficiency causes white sponge nevus in mice. |
| Volume: |
468 |
| Issue: |
1-2 |
| Pages: |
146-153 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jin J |
| Year: |
2004 |
| Journal: |
Genes Dev |
| Title: |
Systematic analysis and nomenclature of mammalian F-box proteins. |
| Volume: |
18 |
| Issue: |
21 |
| Pages: |
2573-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koss M |
| Year: |
2012 |
| Journal: |
Dev Cell |
| Title: |
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
913-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blackshaw S |
| Year: |
2004 |
| Journal: |
PLoS Biol |
| Title: |
Genomic analysis of mouse retinal development. |
| Volume: |
2 |
| Issue: |
9 |
| Pages: |
E247 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inuzuka H |
| Year: |
2012 |
| Journal: |
Cell |
| Title: |
Acetylation-dependent regulation of Skp2 function. |
| Volume: |
150 |
| Issue: |
1 |
| Pages: |
179-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shim EH |
| Year: |
2003 |
| Journal: |
Cancer Res |
| Title: |
Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate. |
| Volume: |
63 |
| Issue: |
7 |
| Pages: |
1583-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cai Z |
| Year: |
2020 |
| Journal: |
Semin Cancer Biol |
| Title: |
The Skp2 Pathway: A Critical Target for Cancer Therapy. |
| Volume: |
67 |
| Issue: |
Pt 2 |
| Pages: |
16-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu XL |
| Year: |
2017 |
| Journal: |
Cancer Res |
| Title: |
SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells. |
| Volume: |
77 |
| Issue: |
24 |
| Pages: |
6838-6850 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2021 |
| Journal: |
Ann N Y Acad Sci |
| Title: |
The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma. |
| Volume: |
1490 |
| Issue: |
1 |
| Pages: |
90-104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song P |
| Year: |
2011 |
| Journal: |
Circ Res |
| Title: |
AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells. |
| Volume: |
109 |
| Issue: |
11 |
| Pages: |
1230-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2021 |
| Journal: |
Oncogene |
| Title: |
EAG1 enhances hepatocellular carcinoma proliferation by modulating SKP2 and metastasis through pseudopod formation. |
| Volume: |
40 |
| Issue: |
1 |
| Pages: |
163-176 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sicari BM |
| Year: |
2012 |
| Journal: |
Endocrinology |
| Title: |
c-myc and skp2 coordinate p27 degradation, vascular smooth muscle proliferation, and neointima formation induced by the parathyroid hormone-related protein. |
| Volume: |
153 |
| Issue: |
2 |
| Pages: |
861-72 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu L |
| Year: |
2009 |
| Journal: |
Cancer Res |
| Title: |
Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222. |
| Volume: |
69 |
| Issue: |
8 |
| Pages: |
3374-81 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
S-phase kinase-associated protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang GZ |
| Year: |
2020 |
| Journal: |
bioRxiv |
| Title: |
Degradation of SARS-CoV-2 receptor ACE2 by tobacco carcinogen-induced Skp2 in lung epithelial cells Running title: ACE2 catabolism in lung epithelial cells. |
|
|
|
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Michel JJ |
| Year: |
1998 |
| Journal: |
Cell Growth Differ |
| Title: |
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
435-49 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
424
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
354
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 4, Michele Pagano |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 31, Hui Zhang |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 33, Hui Zhang |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(SKP2)4Paga/? |
| Background: |
involves: C57BL/6 * DBA/2 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 79, Hui Zhang |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ilyin GP |
| Year: |
2000 |
| Journal: |
Genomics |
| Title: |
cDNA cloning and expression analysis of new members of the mammalian F-box protein family. |
| Volume: |
67 |
| Issue: |
1 |
| Pages: |
40-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu WN |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration. |
| Volume: |
12 |
| Issue: |
4 |
| Pages: |
610-21 |
|
•
•
•
•
•
|