Type |
Details |
Score |
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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•
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•
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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•
•
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
MGI Sequence Curation Reference |
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•
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•
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
•
•
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•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
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Title: |
Cyagen Biosciences Website. |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
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•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
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•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
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•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
transgene insertion 1, Paul M Allen |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
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Strain |
Attribute String: |
coisogenic, mutant strain, transgenic |
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Publication |
First Author: |
Buxbaum J |
Year: |
2006 |
Journal: |
Gastroenterology |
Title: |
Novel model of antigen-specific induction of bile duct injury. |
Volume: |
131 |
Issue: |
6 |
Pages: |
1899-906 |
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•
•
•
•
•
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Publication |
First Author: |
Groen A |
Year: |
2011 |
Journal: |
Gastroenterology |
Title: |
Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity. |
Volume: |
141 |
Issue: |
5 |
Pages: |
1927-37.e1-4 |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
103
 |
Fragment?: |
true |
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•
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•
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Publication |
First Author: |
Bull LN |
Year: |
1998 |
Journal: |
Nat Genet |
Title: |
A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. |
Volume: |
18 |
Issue: |
3 |
Pages: |
219-24 |
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•
•
•
•
•
|
Publication |
First Author: |
Verhulst PM |
Year: |
2010 |
Journal: |
Hepatology |
Title: |
A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. |
Volume: |
51 |
Issue: |
6 |
Pages: |
2049-60 |
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•
•
•
•
•
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Publication |
First Author: |
Paulusma CC |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity. |
Volume: |
47 |
Issue: |
1 |
Pages: |
268-78 |
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•
•
•
•
•
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Publication |
First Author: |
van der Mark VA |
Year: |
2016 |
Journal: |
Biochim Biophys Acta |
Title: |
The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator. |
Volume: |
1863 |
Issue: |
9 |
Pages: |
2280-8 |
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•
•
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|
Protein Domain |
Type: |
Family |
Description: |
Phospholipid-transporting ATPase IC (also known as ATP8B1 or ATPIC) belongs to subfamily IV of the P-type ATPases family, whose members transport phospholipids across the membrane. ATP8B1 can bind either CDC50A or CDC50B as its accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity [, , ].In hepatocytes, ATP8B1 localises in the canalicular membrane, where it may maintain the membrane integrity and to the function of ABCB4, an ABC floppase that play a role in bile export []. In the epithelial Caco-2 cells, ATP8B1 is required for apical protein expression and microvillus formation in polarised epithelial cells []. Mutations in ATP8B1 cause two forms of intrahepatic cholestasis, progressive familial intrahepatic cholestasis (PFIC) and benign recurrent intrahepatic cholestasis (BFIC) []. It is involved in the correct apical membrane localization of CDC42, CFTR and SLC10A2 []. |
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•
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Publication |
First Author: |
Bryde S |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery. |
Volume: |
285 |
Issue: |
52 |
Pages: |
40562-72 |
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•
•
•
•
•
|
Publication |
First Author: |
van der Velden LM |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases. |
Volume: |
285 |
Issue: |
51 |
Pages: |
40088-96 |
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•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
245
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1251
 |
Fragment?: |
false |
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•
•
•
•
|