Type |
Details |
Score |
Genotype |
Symbol: |
Cebpd/Cebpd |
Background: |
involves: 129S1/Sv * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cebpd/Cebpd |
Background: |
involves: 129S1/Sv |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cebpd/Cebpd<+> |
Background: |
involves: 129S1/Sv |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Tomita T |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. |
Volume: |
283 |
Issue: |
37 |
Pages: |
25617-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko CY |
Year: |
2015 |
Journal: |
Neurobiol Aging |
Title: |
CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease. |
Volume: |
36 |
Issue: |
3 |
Pages: |
1356-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko CY |
Year: |
2014 |
Journal: |
Neurobiol Aging |
Title: |
Glycogen synthase kinase-3β-mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promotes migration and activation of microglia/macrophages. |
Volume: |
35 |
Issue: |
1 |
Pages: |
24-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lutzenberger M |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer's Disease Model. |
Volume: |
10 |
Issue: |
7 |
Pages: |
e0134228 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu YY |
Year: |
2016 |
Journal: |
Mol Neurobiol |
Title: |
Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a. |
Volume: |
53 |
Issue: |
6 |
Pages: |
4173-4188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Valente T |
Year: |
2020 |
Journal: |
Cell Death Differ |
Title: |
CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein. |
Volume: |
27 |
Issue: |
2 |
Pages: |
509-524 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the solute-binding domain found in Sodium-coupled monocarboxylate transporter 2 (SMCT2). SMCT2 is a low-affinity transporter for short-chain fatty acids, lactate, pyruvate, and nicotinate. Human SMCT2 (hSMCT2) is encoded by the SLC5A12 gene []. SMCT2 is expressed in the kidney, small intestine, skeletal muscle, and retina. In the kidney, it is expressed in the apical membrane of the proximal convoluted tubule, along the entire length of the tubule (in contrast to the high-affinity monocarboxylate transporter SMCT1, belonging to a different family, which is limited to the S3 segment of the tubule) []. SMCT2 may initiate lactate absorption in the early parts of the tubule []. In the retina, SMCT1 and SMCT2 may play a differential role in monocarboxylate transport in a cell type-specific manner, SMCT2 is expressed exclusively in Muller cells []. SMCT2 belongs to the solute carrier 5 (SLC5) transporter family []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang K |
Year: |
2012 |
Journal: |
FASEB J |
Title: |
Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption. |
Volume: |
26 |
Issue: |
1 |
Pages: |
259-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wright EM |
Year: |
2004 |
Journal: |
Physiology (Bethesda) |
Title: |
Surprising versatility of Na+-glucose cotransporters: SLC5. |
Volume: |
19 |
|
Pages: |
370-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balamurugan K |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis. |
Volume: |
29 |
Issue: |
24 |
Pages: |
4106-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balamurugan K |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4. |
Volume: |
4 |
|
Pages: |
1662 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin PM |
Year: |
2007 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Expression of the sodium-coupled monocarboxylate transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in retina. |
Volume: |
48 |
Issue: |
7 |
Pages: |
3356-63 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
619
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|