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Search results 101 to 126 out of 126 for Slfn4

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Type Details Score
Protein Domain
IPR029671 | Slfn5
Type: Family
Description: The Schlafen (SLFN) family includes several mouse and human member genes that have been implicated in important functions, such as the control of cell proliferation, induction of immune responses, and the regulation of viral replication [, , , ]. Mouse and human SLFN proteins are regulated by interferons (IFNs) []. All SLFNs contain an unique Slfn box. SLFN family is comprised of 3 groups, based on the size of the encoded proteins [, , , ]:Group1: Slfn1, Slfn2, and Slfn Like 1.Group2: Slfn3, Slfn4 and Slfn12.Group3: Slfn5, Slfn8-11, Slfn13 and Slfn14.Comparing to group1 proteins, group2 and 3 proteins contain an extra SWADL domain C terminus to the AAA domain. Group3 proteins also possess a large extension C terminus to their SWADL domain. This C-terminal extension is homologous to the superfamily I of DNA/RNA helicases []. It has been proposed that the divergent AAA ATPase domain may function as an RNA-binding domain []. Slfn5 has a role in hematopoietic cell differentiation []. Human Slfn5 has been shown to exhibit negative regulatory effects on anchorage-independent malignant melanoma cell growth and invasion in collagen [].
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Protein
V9GXG1
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
A0A1G5SK54
Organism: Mus musculus/domesticus
Length: 898  
Fragment?: false
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Protein
A0A1G5SK34
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
Q8R3R7
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: false
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Protein
A0A5H1ZRL4
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: true
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Protein
A0A5H1ZRL2
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: true
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Protein
A0A1G5SJI4
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: true
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Protein
A0A5H1ZRM2
Organism: Mus musculus/domesticus
Length: 417  
Fragment?: true
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Protein
A0A1G5SK24
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
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Protein
Q8CBA2
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SJC0
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SK44
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SJR4
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
B1ARD8
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
B1ARD6
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SJB6
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SL47
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SJ80
Organism: Mus musculus/domesticus
Length: 928  
Fragment?: false
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Protein
A0A1G5SL26
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
A0A1G5SJ64
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
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Protein
Q7TMF0
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SJ89
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SJA0
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
A0A1G5SLJ2
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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