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Search results 101 to 122 out of 122 for Slu7

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0.011s

Type

Details

Score

Strain

MGI:6122451 | C57BL/6NTac-Slu7<tm1a(KOMP)Wtsi>/WtsiPh

Attribute String:

mutant strain, coisogenic, targeted mutation

•

Strain

MGI:7591488 | C57BL/6J-Slu7<em1Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7797393 | C57BL/6JCya-Slu7<em2Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7835288 | C57BL/6JCya-Slu7<em3Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Genotype

Symbol:	Slu7/Slu7
Background:	C57BL/6N-Slu7/Wtsi
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Slu7/Slu7<+>
Background:	C57BL/6N-Slu7/Wtsi
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Slu7/Slu7<+>
Background:	C57BL/6NTac-Slu7/WtsiPh
Zygosity:	ht
Has Mutant Allele:	true

•

Publication

17045351 | -

First Author:	Montaville P
Year:	2006
Journal:	Biochim Biophys Acta
Title:	Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.
Volume:	1763
Issue:	11
Pages:	1335-43

•

Publication

9528778 | -

First Author:	Xu D
Year:	1998
Journal:	Mol Cell Biol
Title:	Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.
Volume:	18
Issue:	4
Pages:	2055-66

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Protein Domain

IPR039171 | Cwc2/Slt11

Type:

Family

Description:

This entry contains proteins involved in the first step of pre-mRNA splicing to remove introns. Splicing is performed by the spliceosome, which is a complex of snRNAs U1, U2, U4, U5, and U6 and proteins such as pre-mRNA-processing factor 19 (Prp19). The yeast protein Cwc2 contains motifs known to bind RNA, a zinc finger and an RNA recognition motif. Because mutations in the gene are lethal and lead to accumulation of pre-mRNA, and reduced levels of U1, U4, U5 and U6 snRNAs and U4/U6 snRNA complex levels, Cwc2 has been proposed to link the Prp19 complex to the spliceosome during pre-mRNA splicing []. Because Cwc2 is at the spliceosome catalytic centre, it induces an active conformation of the spliceosome's catalytic RNA elements []. Cwc2 is a component of the CWC complex []. The human homologue, known as RBM22 [], also translocates the protein SLU7 from the nucleus to the cytoplasm or vice versa in the case of the calcium-binding protein PDCD6 [].Also included in this entry is the pre-mRNA-splicing factor Slt11 (also known as Ecm2) [].

•

Protein

A2RT18

Organism:	Mus musculus/domesticus
Length:	1139
Fragment?:	false

•

Protein

F6WNY1

Organism:	Mus musculus/domesticus
Length:	1150
Fragment?:	true

•

Protein

Q99MW8

Organism:	Mus musculus/domesticus
Length:	1139
Fragment?:	false

•

Publication

22246180 | -

First Author:	Rasche N
Year:	2012
Journal:	EMBO J
Title:	Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre.
Volume:	31
Issue:	6
Pages:	1591-604

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Publication

19435883 | -

First Author:	McGrail JC
Year:	2009
Journal:	Nucleic Acids Res
Title:	The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing.
Volume:	37
Issue:	13
Pages:	4205-17

•

Protein

Q8BHS3

Organism:	Mus musculus/domesticus
Length:	420
Fragment?:	false

•

Publication

11884590 | -

First Author:	Ohi MD
Year:	2002
Journal:	Mol Cell Biol
Title:	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.
Volume:	22
Issue:	7
Pages:	2011-24

•

Publication

19144319 | J:143718

First Author:	Trost M
Year:	2009
Journal:	Immunity
Title:	The phagosomal proteome in interferon-gamma-activated macrophages.
Volume:	30
Issue:	1
Pages:	143-54

•

Publication

16141072 | J:99680

First Author:	Carninci P
Year:	2005
Journal:	Science
Title:	The transcriptional landscape of the mammalian genome.
Volume:	309
Issue:	5740
Pages:	1559-63

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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