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Search results 101 to 200 out of 223 for Slx4

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
431903 | slx4ip.S
Type: gene
Organism: frog, African clawed
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Strain
MGI:6476336 | C57BL/6JSmoc-Slx4<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Gene
432277 | slx4.L
Type: gene
Organism: frog, African clawed
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Publication
22911665 | -
First Author: Bakker JL
Year: 2013
Journal: Hum Mutat
Title: Analysis of the novel fanconi anemia gene SLX4/FANCP in familial breast cancer cases.
Volume: 34
Issue: 1
Pages: 70-3
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Protein
F6XZI3
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
E9PYE7
Organism: Mus musculus/domesticus
Length: 35  
Fragment?: true
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Protein
E9Q0M1
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
F6R0R3
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
F7A9G8
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: true
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Publication
18471978 | -
First Author: Li F
Year: 2008
Journal: Mol Cell
Title: Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates.
Volume: 30
Issue: 3
Pages: 325-35
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Allele
Slx4<tm1.2Jrou> | MGI:5559219
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1.2, John Rouse
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Slx4ip<+> | MGI:5442429
 
Name: SLX4 interacting protein; wild type
Allele Type: Not Specified
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Publication
12832395 | -
First Author: Fricke WM
Year: 2003
Journal: Genes Dev
Title: Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.
Volume: 17
Issue: 14
Pages: 1768-78
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Protein Coding Gene
MGP_CAROLIEiJ_G0024359 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026561 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025804 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025279 | -
Type: protein_coding_gene
Organism: Mus spretus
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Allele
Slx4ip<Gt(RRH082)Byg> | MGI:4128868
 
Name: SLX4 interacting protein; gene trap RRH082, BayGenomics
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(RRF521)Byg> | MGI:4129095
 
Name: SLX4 interacting protein; gene trap RRF521, BayGenomics
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(XK413)Byg> | MGI:4129357
 
Name: SLX4 interacting protein; gene trap XK413, BayGenomics
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: B6.129P2-Slx4
Zygosity: hm
Has Mutant Allele: true
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Publication
21464321 | -
First Author: Yamamoto KN
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.
Volume: 108
Issue: 16
Pages: 6492-6
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Allele
Slx4<+> | MGI:3050981
   
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); wild type
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Allele
Slx4ip<Gt(XS0273)Wtsi> | MGI:3877323
 
Name: SLX4 interacting protein; gene trap XS0273, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(D175E12)Wrst> | MGI:3892939
 
Name: SLX4 interacting protein; gene trap D175E12, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(D181E12)Wrst> | MGI:3893117
 
Name: SLX4 interacting protein; gene trap D181E12, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(OST78908)Lex> | MGI:4175941
 
Name: SLX4 interacting protein; gene trap OST78908, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(OST313053)Lex> | MGI:4276055
 
Name: SLX4 interacting protein; gene trap OST313053, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(OST452546)Lex> | MGI:4322366
 
Name: SLX4 interacting protein; gene trap OST452546, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(AM0623)Wtsi> | MGI:4345536
 
Name: SLX4 interacting protein; gene trap AM0623, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(AS0345)Wtsi> | MGI:4346691
 
Name: SLX4 interacting protein; gene trap AS0345, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slx4ip<tm1a(EUCOMM)Wtsi> | MGI:4433347
Name: SLX4 interacting protein; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Slx4ip<tm1e(EUCOMM)Wtsi> | MGI:4433589
Name: SLX4 interacting protein; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Slx4ip<tm1b(EUCOMM)Wtsi> | MGI:6416319
Name: SLX4 interacting protein; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Interaction Experiment
Nair N (2014)
Description: Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein.
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Interaction Experiment
Gonzalez-Prieto R (2015)
Description: SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites.
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Publication
25224045 | -
 
First Author: Nair N
Year: 2014
Journal: DNA Repair (Amst)
Title: Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein.
Volume: 24
Pages: 131-137
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Publication
25722289 | -
First Author: González-Prieto R
Year: 2015
Journal: EMBO Rep
Title: SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites.
Volume: 16
Issue: 4
Pages: 512-9
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Interaction Experiment
Hodskinson MR (2014)
Description: Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.
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Allele
Slx4<tm1a(EUCOMM)Wtsi> | MGI:4432843
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:5776740 | C57BL/6N-Slx4ip<tm1a(EUCOMM)Wtsi>/Wtsi
Attribute String: coisogenic, targeted mutation
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Allele
Slx4<tm1e(EUCOMM)Wtsi> | MGI:4434506
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Slx4ip<Gt(IST13206C2)Tigm> | MGI:5155052
 
Name: SLX4 interacting protein; gene trap IST13206C2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(IST14595B4)Tigm> | MGI:5244856
 
Name: SLX4 interacting protein; gene trap IST14595B4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(IST14639F6)Tigm> | MGI:5247114
 
Name: SLX4 interacting protein; gene trap IST14639F6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(IST14666C9)Tigm> | MGI:5249746
 
Name: SLX4 interacting protein; gene trap IST14666C9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Slx4ip<Gt(IST15065C12)Tigm> | MGI:5277169
 
Name: SLX4 interacting protein; gene trap IST15065C12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Slx4<tm1Jrou> | MGI:5552807
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1, John Rouse
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Slx4<tm1.1Jrou> | MGI:5559218
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); targeted mutation 1.1, John Rouse
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Slx4<m1Btlr> | MGI:5806336
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6428031 | C57BL/6N-Slx4ip<tm1b(EUCOMM)Wtsi>/WtsiH
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Slx4ip/Slx4ip
Background: C57BL/6N-Slx4ip/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5557225 | B6NTac;B6N-Slx4ip<tm1a(EUCOMM)Wtsi> A<tm1Brd>/WtsiH
Attribute String: mutant strain, targeted mutation, coisogenic
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Strain
MGI:6347364 | C57BL/6N-Slx4<tm1a(EUCOMM)Wtsi>/MbpMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5781356 | B6JTyr;B6N-Slx4<tm1a(EUCOMM)Wtsi>/Wtsi
Attribute String: mutant stock, targeted mutation
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Strain
MGI:4938614 | C57BL/6N-Slx4<tm1a(EUCOMM)Wtsi>
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5559581 | B6.129P2-Slx4<tm1.2Jrou>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5807174 | C57BL/6J-Slx4<m1Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: C57BL/6N-Slx4
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: B6JTyr;B6N-Slx4/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slx4/Slx4
Background: C57BL/6J-Slx4
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0111092 | Fanconi anemia complementation group P
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Strain
MGI:5556489 | B6Brd;B6N-Tyr<c-Brd> Slx4<tm1a(EUCOMM)Wtsi>/WtsiCnbc
Attribute String: mutant strain, targeted mutation, spontaneous mutation
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Genotype
Genotype
Symbol: Fan1/Fan1 Slx4/Slx4
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slx4/Slx4<+>
Background: B6JTyr;B6N-Slx4/Wtsi
Zygosity: ht
Has Mutant Allele: true
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Protein Domain
IPR027784 | Slx4_ascomycetes
Type: Family
Description: The Slx4 protein is an endonuclease involved in processing DNA. In Saccharomyces cerevisiae, Slx4 forms complex with Slx1 that acts as a nuclease on branched DNA substrates, particularly simple-Y, 5'-flap, or replication fork structures by cleaving the strand bearing the 5' non-homologous arm at the branch junction and thus generating ligatable nicked products from 5'-flap or replication fork substrates [, ]. It is also involved in interstrand cross-link repair and in Rad1/Rad10-dependent processing of recombination intermediates[].
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Publication
27010503 | J:235782
First Author: Braun J
Year: 2016
Journal: PLoS One
Title: The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis.
Volume: 11
Issue: 3
Pages: e0152278
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Publication
26941064 | J:236339
 
First Author: Rai R
Year: 2016
Journal: Nat Commun
Title: TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.
Volume: 7
Pages: 10881
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Protein
Q80V62
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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Protein
B2RSU4
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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Protein
Q3U202
Organism: Mus musculus/domesticus
Length: 1429  
Fragment?: true
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Protein
Q3TLN3
Organism: Mus musculus/domesticus
Length: 1144  
Fragment?: true
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Protein
A0A0N4SV29
Organism: Mus musculus/domesticus
Length: 1437  
Fragment?: false
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Protein
A0A0N4SVS0
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
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Protein
Q3UQJ0
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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Publication
23444773 | -
First Author: Yao CJ
Year: 2013
Journal: Pharmazie
Title: Fanconi anemia pathway--the way of DNA interstrand cross-link repair.
Volume: 68
Issue: 1
Pages: 5-11
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Publication
11530803 | -
First Author: Yamashita T
Year: 2001
Journal: Int J Hematol
Title: Current knowledge on the pathophysiology of Fanconi anemia: from genes to phenotypes.
Volume: 74
Issue: 1
Pages: 33-41
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Publication
20603073 | -
First Author: Smogorzewska A
Year: 2010
Journal: Mol Cell
Title: A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
Volume: 39
Issue: 1
Pages: 36-47
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Publication
20603016 | -
First Author: Kratz K
Year: 2010
Journal: Cell
Title: Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.
Volume: 142
Issue: 1
Pages: 77-88
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Publication
20603015 | -
First Author: MacKay C
Year: 2010
Journal: Cell
Title: Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
Volume: 142
Issue: 1
Pages: 65-76
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Publication
22753026 | -
First Author: Sareen A
Year: 2012
Journal: Nucleic Acids Res
Title: Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase.
Volume: 40
Issue: 17
Pages: 8425-39
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Publication
23658231 | -
First Author: Chaudhury I
Year: 2013
Journal: Nucleic Acids Res
Title: FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery.
Volume: 41
Issue: 13
Pages: 6444-59
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Publication
24556218 | -
First Author: Yeo JE
Year: 2014
Journal: Hum Mol Genet
Title: CtIP mediates replication fork recovery in a FANCD2-regulated manner.
Volume: 23
Issue: 14
Pages: 3695-705
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