Type |
Details |
Score |
Publication |
First Author: |
Hachimine D |
Year: |
2008 |
Journal: |
Int J Oncol |
Title: |
Involvement of Smad3 phosphoisoform-mediated signaling in the development of colonic cancer in IL-10-deficient mice. |
Volume: |
32 |
Issue: |
6 |
Pages: |
1221-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong DH |
Year: |
2013 |
Journal: |
Int J Mol Sci |
Title: |
Smad3 deficiency ameliorates hepatic fibrogenesis through the expression of senescence marker protein-30, an antioxidant-related protein. |
Volume: |
14 |
Issue: |
12 |
Pages: |
23700-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia M |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity. |
Volume: |
8 |
|
Pages: |
15818 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tannehill-Gregg SH |
Year: |
2004 |
Journal: |
Vet Pathol |
Title: |
The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice. |
Volume: |
41 |
Issue: |
3 |
Pages: |
278-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang YA |
Year: |
2006 |
Journal: |
Cancer Cell |
Title: |
Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2. |
Volume: |
9 |
Issue: |
6 |
Pages: |
445-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
McDowell CM |
Year: |
2013 |
Journal: |
Exp Eye Res |
Title: |
Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice. |
Volume: |
116 |
|
Pages: |
419-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Latella G |
Year: |
2009 |
Journal: |
Liver Int |
Title: |
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice. |
Volume: |
29 |
Issue: |
7 |
Pages: |
997-1009 |
|
•
•
•
•
•
|
Publication |
First Author: |
Latella G |
Year: |
2009 |
Journal: |
Eur J Clin Invest |
Title: |
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis. |
Volume: |
39 |
Issue: |
2 |
Pages: |
145-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Domino SE |
Year: |
2007 |
Journal: |
Tumour Biol |
Title: |
Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation. |
Volume: |
28 |
Issue: |
2 |
Pages: |
77-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. |
Volume: |
12 |
Issue: |
10 |
Pages: |
e1006352 |
|
•
•
•
•
•
|
Publication |
First Author: |
Labbé E |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. |
Volume: |
2 |
Issue: |
1 |
Pages: |
109-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Z |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. |
Volume: |
8 |
|
Pages: |
14570 |
|
•
•
•
•
•
|
Publication |
First Author: |
He H |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
Smad3 Mediates Diabetic Dyslipidemia and Fatty Liver in db/db Mice by Targeting PPARδ. |
Volume: |
24 |
Issue: |
14 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mori H |
Year: |
2015 |
Journal: |
Am J Pathol |
Title: |
Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. |
Volume: |
185 |
Issue: |
10 |
Pages: |
2742-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alvarez J |
Year: |
2004 |
Journal: |
Dev Dyn |
Title: |
Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture. |
Volume: |
230 |
Issue: |
4 |
Pages: |
685-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duan WJ |
Year: |
2014 |
Journal: |
Am J Pathol |
Title: |
Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro. |
Volume: |
184 |
Issue: |
8 |
Pages: |
2275-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trotta R |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells. |
Volume: |
181 |
Issue: |
6 |
Pages: |
3784-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2010 |
Journal: |
Diabetes |
Title: |
Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy. |
Volume: |
59 |
Issue: |
10 |
Pages: |
2612-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong X |
Year: |
2020 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells. |
Volume: |
10 |
Issue: |
2 |
Pages: |
341-364 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ding H |
Year: |
2020 |
Journal: |
J Cell Mol Med |
Title: |
Smad3 gene C-terminal phosphorylation site mutation aggravates CCl4 -induced inflammation in mice. |
Volume: |
24 |
Issue: |
12 |
Pages: |
7044-7054 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SY |
Year: |
2011 |
Journal: |
Mol Cell Endocrinol |
Title: |
A truncated, activin-induced Smad3 isoform acts as a transcriptional repressor of FSHβ expression in mouse pituitary. |
Volume: |
342 |
Issue: |
1-2 |
Pages: |
64-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Howell M |
Year: |
2001 |
Journal: |
Mech Dev |
Title: |
Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart. |
Volume: |
104 |
Issue: |
1-2 |
Pages: |
147-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. |
Volume: |
28 |
Issue: |
23 |
Pages: |
7001-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sriram S |
Year: |
2014 |
Journal: |
Mol Endocrinol |
Title: |
Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle. |
Volume: |
28 |
Issue: |
3 |
Pages: |
317-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goodman CA |
Year: |
2013 |
Journal: |
Mol Endocrinol |
Title: |
Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo. |
Volume: |
27 |
Issue: |
11 |
Pages: |
1946-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun JG |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signaling. |
Volume: |
7 |
Issue: |
9 |
Pages: |
9692-706 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kremer M |
Year: |
2014 |
Journal: |
Transpl Int |
Title: |
Smad3 signaling in the regenerating liver: implications for the regulation of IL-6 expression. |
Volume: |
27 |
Issue: |
7 |
Pages: |
748-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono H |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy. |
Volume: |
8 |
Issue: |
1 |
Pages: |
10548 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheng J |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression. |
Volume: |
11 |
Issue: |
6 |
Pages: |
2845-2859 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumari R |
Year: |
2021 |
Journal: |
FASEB J |
Title: |
SMAD2 and SMAD3 differentially regulate adiposity and the growth of subcutaneous white adipose tissue. |
Volume: |
35 |
Issue: |
12 |
Pages: |
e22018 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong Y |
Year: |
2013 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Interactions between p-Akt and Smad3 in injured muscles initiate myogenesis or fibrogenesis. |
Volume: |
305 |
Issue: |
3 |
Pages: |
E367-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsurutani Y |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The roles of transforming growth factor-β and Smad3 signaling in adipocyte differentiation and obesity. |
Volume: |
407 |
Issue: |
1 |
Pages: |
68-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suh JH |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Orphan nuclear receptor small heterodimer partner inhibits transforming growth factor-beta signaling by repressing SMAD3 transactivation. |
Volume: |
281 |
Issue: |
51 |
Pages: |
39169-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dunn NR |
Year: |
2004 |
Journal: |
Development |
Title: |
Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo. |
Volume: |
131 |
Issue: |
8 |
Pages: |
1717-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2007 |
Journal: |
Exp Neurol |
Title: |
Smad3 null mice display more rapid wound closure and reduced scar formation after a stab wound to the cerebral cortex. |
Volume: |
203 |
Issue: |
1 |
Pages: |
168-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKarns SC |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation. |
Volume: |
172 |
Issue: |
7 |
Pages: |
4275-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winbanks CE |
Year: |
2012 |
Journal: |
J Cell Biol |
Title: |
Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin. |
Volume: |
197 |
Issue: |
7 |
Pages: |
997-1008 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tapia-González S |
Year: |
2013 |
Journal: |
Cell Commun Signal |
Title: |
Smad3 is required for the survival of proliferative intermediate progenitor cells in the dentate gyrus of adult mice. |
Volume: |
11 |
|
Pages: |
93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao J |
Year: |
1998 |
Journal: |
Dev Biol |
Title: |
Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture. |
Volume: |
194 |
Issue: |
2 |
Pages: |
182-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim EY |
Year: |
2011 |
Journal: |
FEBS Lett |
Title: |
Lipopolysaccharide inhibits transforming growth factor-beta1-stimulated Smad6 expression by inducing phosphorylation of the linker region of Smad3 through a TLR4-IRAK1-ERK1/2 pathway. |
Volume: |
585 |
Issue: |
5 |
Pages: |
779-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Philipp-Staheli J |
Year: |
2002 |
Journal: |
Cancer Cell |
Title: |
Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. |
Volume: |
1 |
Issue: |
4 |
Pages: |
355-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Looyenga BD |
Year: |
2007 |
Journal: |
Mol Endocrinol |
Title: |
Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery. |
Volume: |
21 |
Issue: |
10 |
Pages: |
2440-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li LF |
Year: |
2015 |
Journal: |
Respir Res |
Title: |
Activation of Src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury. |
Volume: |
16 |
|
Pages: |
112 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flanders KC |
Year: |
2003 |
Journal: |
Am J Pathol |
Title: |
Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin. |
Volume: |
163 |
Issue: |
6 |
Pages: |
2247-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Islam R |
Year: |
2018 |
Journal: |
J Cell Physiol |
Title: |
Peptidyl-prolyl cis-trans isomerase NIMA interacting 1 regulates skeletal muscle fusion through structural modification of Smad3 in the linker region. |
Volume: |
233 |
Issue: |
12 |
Pages: |
9390-9403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park BV |
Year: |
2016 |
Journal: |
Cancer Discov |
Title: |
TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer. |
Volume: |
6 |
Issue: |
12 |
Pages: |
1366-1381 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugiyama Y |
Year: |
2012 |
Journal: |
Int Immunol |
Title: |
Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways. |
Volume: |
24 |
Issue: |
4 |
Pages: |
253-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen B |
Year: |
2022 |
Journal: |
J Mol Cell Cardiol |
Title: |
Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium. |
Volume: |
171 |
|
Pages: |
1-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fortin J |
Year: |
2014 |
Journal: |
FASEB J |
Title: |
Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells. |
Volume: |
28 |
Issue: |
3 |
Pages: |
1474-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun YB |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Endothelial dysfunction exacerbates renal interstitial fibrosis through enhancing fibroblast Smad3 linker phosphorylation in the mouse obstructed kidney. |
Volume: |
8 |
Issue: |
12 |
Pages: |
e84063 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakurai A |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy. |
Volume: |
14 |
Issue: |
5 |
Pages: |
e0216788 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kocic J |
Year: |
2012 |
Journal: |
Eur J Cancer |
Title: |
SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes. |
Volume: |
48 |
Issue: |
10 |
Pages: |
1550-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Umezu T |
Year: |
2021 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Smad2 and Smad3 expressed in skeletal muscle promote immobilization-induced bone atrophy in mice. |
Volume: |
582 |
|
Pages: |
111-117 |
|
•
•
•
•
•
|
Publication |
First Author: |
Falanga V |
Year: |
2004 |
Journal: |
Wound Repair Regen |
Title: |
Full-thickness wounding of the mouse tail as a model for delayed wound healing: accelerated wound closure in Smad3 knock-out mice. |
Volume: |
12 |
Issue: |
3 |
Pages: |
320-6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6431055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7281830 |
Age: |
embryonic day 14.5 |
Image: |
4C |
Note: |
Sample was from cerebral cortex. Phosphorylated Smad3 expression level was reduced in the mutant. |
Specimen Label: |
4C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6431055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7281830 |
Age: |
embryonic day 14.5 |
Image: |
4D |
Note: |
Sample was from midbrain. Phosphorylated Smad3 expression level was reduced in the mutant. |
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6431055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7281830 |
Age: |
embryonic day 14.5 |
Image: |
4J |
Note: |
Sample was from cerebral cortex. Phosphorylated Smad3 expression level was reduced in the mutant. |
Specimen Label: |
4J |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6431055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7281830 |
Age: |
embryonic day 14.5 |
Image: |
4K |
Note: |
Sample was from midbrain. Phosphorylated Smad3 expression level was reduced in the mutant. |
Specimen Label: |
4K |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
2008 |
Journal: |
Arthritis Rheum |
Title: |
Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice. |
Volume: |
58 |
Issue: |
10 |
Pages: |
3132-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hama T |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease. |
Volume: |
313 |
Issue: |
6 |
Pages: |
F1223-F1231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang S |
Year: |
2020 |
Journal: |
Biochim Biophys Acta Mol Cell Res |
Title: |
The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice. |
Volume: |
1867 |
Issue: |
7 |
Pages: |
118703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borton AJ |
Year: |
2001 |
Journal: |
J Bone Miner Res |
Title: |
The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis. |
Volume: |
16 |
Issue: |
10 |
Pages: |
1754-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang YA |
Year: |
2002 |
Journal: |
Cell Growth Differ |
Title: |
Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta. |
Volume: |
13 |
Issue: |
3 |
Pages: |
123-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohn EA |
Year: |
2012 |
Journal: |
Mol Cancer Res |
Title: |
Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1389-99 |
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Publication |
First Author: |
Sato F |
Year: |
2019 |
Journal: |
Am J Pathol |
Title: |
Smad3 Suppresses Epithelial Cell Migration and Proliferation via the Clock Gene Dec1, Which Negatively Regulates the Expression of Clock Genes Dec2 and Per1. |
Volume: |
189 |
Issue: |
4 |
Pages: |
773-783 |
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Publication |
First Author: |
Li L |
Year: |
2006 |
Journal: |
Nat Immunol |
Title: |
A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance. |
Volume: |
7 |
Issue: |
11 |
Pages: |
1157-65 |
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Publication |
First Author: |
Xu L |
Year: |
2010 |
Journal: |
Immunity |
Title: |
Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. |
Volume: |
33 |
Issue: |
3 |
Pages: |
313-25 |
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Publication |
First Author: |
Schlenner SM |
Year: |
2012 |
Journal: |
J Exp Med |
Title: |
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut. |
Volume: |
209 |
Issue: |
9 |
Pages: |
1529-35 |
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Publication |
First Author: |
Mishra B |
Year: |
2004 |
Journal: |
Liver Int |
Title: |
Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis. |
Volume: |
24 |
Issue: |
6 |
Pages: |
637-45 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
209
 |
Fragment?: |
true |
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Publication |
First Author: |
Kriseman M |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Uterine double-conditional inactivation of Smad2 and Smad3 in mice causes endometrial dysregulation, infertility, and uterine cancer. |
Volume: |
116 |
Issue: |
9 |
Pages: |
3873-3882 |
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Publication |
First Author: |
Dunn NR |
Year: |
2005 |
Journal: |
Genes Dev |
Title: |
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. |
Volume: |
19 |
Issue: |
1 |
Pages: |
152-63 |
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Publication |
First Author: |
Nold MF |
Year: |
2010 |
Journal: |
Nat Immunol |
Title: |
IL-37 is a fundamental inhibitor of innate immunity. |
Volume: |
11 |
Issue: |
11 |
Pages: |
1014-22 |
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Publication |
First Author: |
Han Y |
Year: |
2018 |
Journal: |
Cell |
Title: |
Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. |
Volume: |
173 |
Issue: |
3 |
Pages: |
634-648.e12 |
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Publication |
First Author: |
Kano K |
Year: |
1999 |
Journal: |
J Vet Med Sci |
Title: |
Cloning and studies of the mouse cDNA encoding Smad3. |
Volume: |
61 |
Issue: |
3 |
Pages: |
213-9 |
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Publication |
First Author: |
Nam KT |
Year: |
2012 |
Journal: |
Lab Invest |
Title: |
Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature. |
Volume: |
92 |
Issue: |
6 |
Pages: |
883-95 |
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Publication |
First Author: |
Wang W |
Year: |
2022 |
Journal: |
Adv Sci (Weinh) |
Title: |
SARS-CoV-2 N Protein Induces Acute Kidney Injury via Smad3-Dependent G1 Cell Cycle Arrest Mechanism. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e2103248 |
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Publication |
First Author: |
Hosokawa R |
Year: |
2005 |
Journal: |
J Invest Dermatol |
Title: |
Functional significance of Smad2 in regulating basal keratinocyte migration during wound healing. |
Volume: |
125 |
Issue: |
6 |
Pages: |
1302-9 |
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Publication |
First Author: |
Huang X |
Year: |
2018 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling. |
Volume: |
38 |
Issue: |
5 |
Pages: |
1086-1101 |
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Publication |
First Author: |
Shirai K |
Year: |
2006 |
Journal: |
Mol Vis |
Title: |
A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling. |
Volume: |
12 |
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Pages: |
681-91 |
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Publication |
First Author: |
Lin HM |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function. |
Volume: |
284 |
Issue: |
18 |
Pages: |
12246-57 |
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Publication |
First Author: |
Ramirez AM |
Year: |
2006 |
Journal: |
Am J Transplant |
Title: |
Myofibroblast transdifferentiation in obliterative bronchiolitis: tgf-beta signaling through smad3-dependent and -independent pathways. |
Volume: |
6 |
Issue: |
9 |
Pages: |
2080-8 |
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Publication |
First Author: |
Vetuschi A |
Year: |
2006 |
Journal: |
Eur J Clin Invest |
Title: |
Smad3-null mice lack interstitial cells of Cajal in the colonic wall. |
Volume: |
36 |
Issue: |
1 |
Pages: |
41-8 |
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Publication |
First Author: |
Ghayur A |
Year: |
2019 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis. |
Volume: |
317 |
Issue: |
1 |
Pages: |
F152-F162 |
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Publication |
First Author: |
Li JH |
Year: |
2009 |
Journal: |
Mol Immunol |
Title: |
Suppressed acute phase response to LPS-induced hepatic injury in Smad3-deficient mice. |
Volume: |
46 |
Issue: |
3 |
Pages: |
362-5 |
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Publication |
First Author: |
Matsuura I |
Year: |
2004 |
Journal: |
Nature |
Title: |
Cyclin-dependent kinases regulate the antiproliferative function of Smads. |
Volume: |
430 |
Issue: |
6996 |
Pages: |
226-31 |
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Publication |
First Author: |
Wang A |
Year: |
2007 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria. |
Volume: |
293 |
Issue: |
5 |
Pages: |
F1657-65 |
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Publication |
First Author: |
Radeke HH |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Overlapping signaling pathways of sphingosine 1-phosphate and TGF-beta in the murine Langerhans cell line XS52. |
Volume: |
174 |
Issue: |
5 |
Pages: |
2778-86 |
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Publication |
First Author: |
Li G |
Year: |
2006 |
Journal: |
Mol Endocrinol |
Title: |
Role of steroid receptor coactivators in glucocorticoid and transforming growth factor beta regulation of plasminogen activator inhibitor gene expression. |
Volume: |
20 |
Issue: |
5 |
Pages: |
1025-34 |
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Publication |
First Author: |
Zhou Q |
Year: |
2015 |
Journal: |
Sci Rep |
Title: |
Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-based Transcriptome Analysis. |
Volume: |
5 |
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Pages: |
17901 |
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Publication |
First Author: |
Esguerra CV |
Year: |
2007 |
Journal: |
Development |
Title: |
Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination. |
Volume: |
134 |
Issue: |
24 |
Pages: |
4381-93 |
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Publication |
First Author: |
Tan NS |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics. |
Volume: |
280 |
Issue: |
18 |
Pages: |
18163-70 |
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Publication |
First Author: |
Yadav H |
Year: |
2011 |
Journal: |
Cell Metab |
Title: |
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. |
Volume: |
14 |
Issue: |
1 |
Pages: |
67-79 |
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Publication |
First Author: |
Hjelmeland AB |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. |
Volume: |
25 |
Issue: |
21 |
Pages: |
9460-8 |
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Publication |
First Author: |
Ring C |
Year: |
2002 |
Journal: |
Genes Dev |
Title: |
The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. |
Volume: |
16 |
Issue: |
7 |
Pages: |
820-35 |
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Publication |
First Author: |
Lee HJ |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Angiopoietin-like protein 2, a chronic inflammatory mediator, is a new target induced by TGF-β1 through a Smad3-dependent mechanism. |
Volume: |
430 |
Issue: |
3 |
Pages: |
981-6 |
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Publication |
First Author: |
Hong HY |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
14-3-3 σ is a new target up-regulated by transforming growth factor-β1 through a Smad3-dependent mechanism. |
Volume: |
432 |
Issue: |
1 |
Pages: |
193-7 |
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Publication |
First Author: |
Du Y |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
Heightened Crescentic Glomerulonephritis in Immune Challenged 129sv Mice Is TGF-β/Smad3 Dependent. |
Volume: |
22 |
Issue: |
4 |
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Publication |
First Author: |
Maggio-Price L |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice. |
Volume: |
66 |
Issue: |
2 |
Pages: |
828-38 |
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Publication |
First Author: |
Epperly MW |
Year: |
2005 |
Journal: |
Exp Hematol |
Title: |
Increased longevity of hematopoiesis in continuous bone marrow cultures and adipocytogenesis in marrow stromal cells derived from Smad3(-/-) mice. |
Volume: |
33 |
Issue: |
3 |
Pages: |
353-62 |
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