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Search results 101 to 200 out of 3206 for Sox10

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Type Details Score
Publication
34425092 | J:333013
First Author: Huang T
Year: 2022
Journal: Gastroenterology
Title: Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects.
Volume: 162
Issue: 1
Pages: 179-192.e11
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Publication
18773071 | J:334545
First Author: Antonellis A
Year: 2008
Journal: PLoS Genet
Title: Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish.
Volume: 4
Issue: 9
Pages: e1000174
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Publication
21491499 | J:171654
First Author: Bremer M
Year: 2011
Journal: Glia
Title: Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve.
Volume: 59
Issue: 7
Pages: 1022-32
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Publication
18786246 | J:141254
 
First Author: Lee KE
Year: 2008
Journal: BMC Genomics
Title: Identification of direct regulatory targets of the transcription factor Sox10 based on function and conservation.
Volume: 9
Pages: 408
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Publication
16822525 | J:114874
First Author: Schlierf B
Year: 2006
Journal: J Mol Biol
Title: Expression of connexin47 in oligodendrocytes is regulated by the Sox10 transcription factor.
Volume: 361
Issue: 1
Pages: 11-21
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Publication
29361054 | J:260791
First Author: Truch K
Year: 2018
Journal: Hum Mol Genet
Title: Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease.
Volume: 27
Issue: 6
Pages: 1078-1092
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Heritable Phenotypic Marker
MGI:3807538 | msp4
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
33082503 | J:298989
First Author: Mertelmeyer S
Year: 2020
Journal: Sci Rep
Title: The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland.
Volume: 10
Issue: 1
Pages: 17807
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Publication
26928066 | J:234565
First Author: He D
Year: 2016
Journal: Nat Neurosci
Title: Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.
Volume: 19
Issue: 5
Pages: 678-89
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Protein
Q80V12
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
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Publication
38546197 | J:350808
First Author: Schmidt AL
Year: 2024
Journal: Glia
Title: The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation.
Volume: 72
Issue: 7
Pages: 1304-1318
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Publication
12417529 | J:80423
First Author: Paratore C
Year: 2002
Journal: Hum Mol Genet
Title: Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease.
Volume: 11
Issue: 24
Pages: 3075-85
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Publication
21308864 | J:338177
First Author: John N
Year: 2011
Journal: Stem Cells
Title: Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells.
Volume: 29
Issue: 4
Pages: 689-99
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Publication
15102707 | J:98431
First Author: Stolt CC
Year: 2004
Journal: Development
Title: Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.
Volume: 131
Issue: 10
Pages: 2349-58
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Publication
16586440 | J:296651
First Author: Deal KK
Year: 2006
Journal: Dev Dyn
Title: Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues.
Volume: 235
Issue: 5
Pages: 1413-32
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Publication
19748502 | J:154462
First Author: Breuskin I
Year: 2009
Journal: Dev Biol
Title: Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti.
Volume: 335
Issue: 2
Pages: 327-39
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Publication
19933217 | J:155544
First Author: Polanco JC
Year: 2010
Journal: Hum Mol Genet
Title: Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.
Volume: 19
Issue: 3
Pages: 506-16
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GXD Expression
GXD Expression
   
Probe: MGI:6159070
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7332913
Age: embryonic day 11.5
Specimen Label: 1H Sox10 Control
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6159070
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7332913
Age: embryonic day 11.5
Note: Expression unaltered compared to control.
Specimen Label: 1H Sox10 Yy1 cko
Detected: true
Specimen Num: 4
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Publication
20457761 | J:162692
First Author: Finzsch M
Year: 2010
Journal: J Cell Biol
Title: Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.
Volume: 189
Issue: 4
Pages: 701-12
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Publication
23575864 | J:196667
First Author: Vogl MR
Year: 2013
Journal: J Neurosci
Title: Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.
Volume: 33
Issue: 15
Pages: 6679-90
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Publication
24718611 | J:215095
First Author: Mao Y
Year: 2014
Journal: PLoS One
Title: Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear.
Volume: 9
Issue: 4
Pages: e94580
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Publication
22037207 | J:191400
First Author: Hodonsky CJ
Year: 2012
Journal: Mol Cell Neurosci
Title: SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter.
Volume: 49
Issue: 2
Pages: 85-96
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Publication
36318265 | J:334235
First Author: Bernhardt C
Year: 2022
Journal: Nucleic Acids Res
Title: KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF.
Volume: 50
Issue: 20
Pages: 11509-11528
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Publication
38791273 | J:348861
 
First Author: Aberle T
Year: 2024
Journal: Int J Mol Sci
Title: Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop.
Volume: 25
Issue: 10
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Publication
36343245 | J:332093
First Author: Szeto IYY
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.
Volume: 119
Issue: 46
Pages: e2122121119
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Publication
14699577 | J:87382
First Author: Hou L
Year: 2004
Journal: Dev Dyn
Title: Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer.
Volume: 229
Issue: 1
Pages: 54-62
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Publication
23935512 | J:213046
First Author: Harris ML
Year: 2013
Journal: PLoS Genet
Title: A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors.
Volume: 9
Issue: 7
Pages: e1003644
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GXD Expression
GXD Expression
 
Probe: MGI:6400500
Assay Type: RNA in situ
Annotation Date: 2020-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6400509
Age: embryonic day 10.5
Note: No difference in expression in peripheral nervous system component derived from neural crest between mutant and control embryos.
Specimen Label: Sox10 E10.5 wt/wt not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6400500
Assay Type: RNA in situ
Annotation Date: 2020-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6400509
Age: embryonic day 10.5
Specimen Label: Sox10 E10.5 m1Will/m1Will not shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3519721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3519722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
   
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3519720
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: false
Specimen Num: 59
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GXD Expression
GXD Expression
   
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3519720
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: false
Specimen Num: 58
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1925221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
   
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1925220
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: false
Specimen Num: 59
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GXD Expression
GXD Expression
   
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1925220
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: false
Specimen Num: 58
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3642221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
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•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7513009
Age: postnatal newborn
Image: 5A Sox10 lacZ/+
Note: The network was similar as in the controls.
Specimen Label: 5A Sox10 lacZ/+
Detected: true
Specimen Num: 63
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GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ si
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ si
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ ce
Note: Trace or absent, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ ce
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2692221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ co
Note: Trace or absent in the colon, presented with colonization delay.
Specimen Label: 1A Sox10 lacZ/+ co
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-p
Specimen Label: 2A Sox10 lacZ/+ si-p
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ si-m
Specimen Label: 2A Sox10 lacZ/+ si-m
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ ce
Specimen Label: 2A Sox10 lacZ/+ ce
Detected: true
Specimen Num: 25
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ co
Note: Colonization delay was seen. No positive cells from the middle of the colon caudally.
Specimen Label: 2A Sox10 lacZ/+ co
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2C Sox10 lacZ/+
Note: Normal neuronal network as in the wild-type.
Specimen Label: 2C Sox10 lacZ/+
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping just before the caecum.
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Note: Slight delay in colonization compared to controls, with the front of migrating enteric neural crest cells in the mutants stopping in the final quarter of the midgut.
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7513009
Age: postnatal newborn
Image: 5A Sox10 lacZ/+
Note: The network was similar as in the controls.
Specimen Label: 5A Sox10 lacZ/+
Detected: true
Specimen Num: 63
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7513009
Age: embryonic day 13.5
Image: 1A Sox10 lacZ/+ s
Note: Fully colonized enteric neural crest cells, similar as in the wild-type.
Specimen Label: 1A Sox10 lacZ/+ s
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7513009
Age: embryonic day 14.5
Image: 2A Sox10 lacZ/+ s
Specimen Label: 2A Sox10 lacZ/+ s
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 beta1-null
Specimen Label: 4B Sox10 beta1-null
Detected: true
Specimen Num: 59
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7512917
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7513009
Age: embryonic day 12.25
Image: 4B Sox10 lacZ/+
Specimen Label: 4B Sox10 lacZ/+
Detected: true
Specimen Num: 58
•
•
•
•
•
Publication
32914934 | J:330661
First Author: Su Z
Year: 2020
Journal: J Cell Mol Med
Title: KIT ligand produced by limbal niche cells under control of SOX10 maintains limbal epithelial stem cell survival by activating the KIT/AKT signalling pathway.
Volume: 24
Issue: 20
Pages: 12020-12031
•
•
•
•
•
Publication
11641219 | J:71878
First Author: Paratore C
Year: 2001
Journal: Development
Title: Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling.
Volume: 128
Issue: 20
Pages: 3949-61
•
•
•
•
•
Publication
20144603 | J:160023
First Author: Cossais F
Year: 2010
Journal: Dev Biol
Title: Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression.
Volume: 341
Issue: 1
Pages: 267-81
•
•
•
•
•
Publication
28063956 | J:242712
First Author: Watanabe Y
Year: 2017
Journal: Gastroenterology
Title: Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2.
Volume: 152
Issue: 5
Pages: 1139-1150.e4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191359
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sox10
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191359
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sox10
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191359
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sox10
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sox10
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sox10
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191359
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sox10
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184025
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191359
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sox10
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3055733
Assay Type: RNA in situ
Annotation Date: 2004-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666816
Pattern: Single cells
Stage: TS16
Assay Id: MGI:3055734
Age: embryonic day 10.0
Image: 6.A
Note: Sox10 marks cell in the Dorsal Root Ganglion of Neural Crest origin.
Specimen Label: 6.A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7595611
Assay Type: RNA in situ
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7595647
Age: embryonic day 8.5-9.0
Image: 6M
Note: Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
Specimen Label: 6M
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7595611
Assay Type: RNA in situ
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7595647
Age: embryonic day 8.5-9.0
Image: 6N
Note: Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
Specimen Label: 6N
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7643365
Assay Type: RNA in situ
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671019
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7643414
Age: embryonic day 11.5
Image: 1F
Note: Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Sox10 was detected in the aggregates.
Specimen Label: 1F
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7643365
Assay Type: RNA in situ
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671019
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7643414
Age: embryonic day 11.5
Note: Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Sox10 was detected in the aggregates.
Specimen Label: not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
24170322 | J:220655
First Author: Harmacek L
Year: 2014
Journal: Dev Neurobiol
Title: A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice.
Volume: 74
Issue: 5
Pages: 483-97
•
•
•
•
•
Publication
- | J:132358
     
First Author: Smart NG
Year: 2008
Journal: MGI Direct Data Submission
Title: Dalmatian, a mouse white spotting coat color mutant allele of Sox10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3055733
Assay Type: RNA in situ
Annotation Date: 2004-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666816
Pattern: Single cells
Stage: TS16
Assay Id: MGI:3055734
Age: embryonic day 10.0
Image: 6.B
Note: Sox10 marks cell in the Dorsal Root Ganglion of Neural Crest origin. Segmentation in the caudal region at the hindlimg level is disturbed
Specimen Label: 6.B
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
23333945 | J:194281
First Author: Silver DL
Year: 2013
Journal: Dev Biol
Title: The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes.
Volume: 375
Issue: 2
Pages: 172-81
•
•
•
•
•
Allele
Mos3 | MGI:4462403
 
Name: modifier of Sox10 3
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Publication
15493017 | J:94207
First Author: Ludwig A
Year: 2004
Journal: Genesis
Title: Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes.
Volume: 40
Issue: 3
Pages: 171-5
•
•
•
•
•
Publication
29074959 | J:255550
First Author: Suzuki N
Year: 2017
Journal: Sci Rep
Title: Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes.
Volume: 7
Issue: 1
Pages: 14133
•
•
•
•
•
Publication
21504042 | J:173518
First Author: Corpening JC
Year: 2011
Journal: Genesis
Title: Isolation and live imaging of enteric progenitors based on Sox10-Histone2BVenus transgene expression.
Volume: 49
Issue: 7
Pages: 599-618
•
•
•
•
•
Publication
10077527 | J:53978
First Author: Southard-Smith EM
Year: 1999
Journal: Genome Res
Title: The Sox10(Dom) mouse: modeling the genetic variation of Waardenburg-Shah (WS4) syndrome.
Volume: 9
Issue: 3
Pages: 215-25
•
•
•
•
•
Publication
32098606 | J:320732
First Author: Yu W
Year: 2020
Journal: Stem Cells Dev
Title: SOX10-Cre-Labeled Cells Under the Tongue Epithelium Serve as Progenitors for Taste Bud Cells That Are Mainly Type III and Keratin 8-Low.
Volume: 29
Issue: 10
Pages: 638-647
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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