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Search results 101 to 200 out of 219 for Sp140

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5310277
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423601
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EB1447; Specimen B391
Detected: false
Specimen Num: 1
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Publication
38029747 | J:343796
First Author: Kotov DI
Year: 2023
Journal: Cell
Title: Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis.
Volume: 186
Issue: 25
Pages: 5536-5553.e22
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Gene
100139208 | SP140L
Type: gene
Organism: cattle
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Gene
737102 | SP140L
Type: gene
Organism: chimpanzee
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Gene
100424943 | SP140L
Type: gene
Organism: macaque, rhesus
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Protein
F6V9G0
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein Coding Gene
MGI:3037746 | Sp140l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
F7DFN7
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
Q6NSQ5
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
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Protein Coding Gene
MGI:3612702 | Sp140l2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
D3Z054
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: false
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Allele
Sp140<+> | MGI:3702468
 
Name: Sp140 nuclear body protein; wild type
Allele Type: Not Specified
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Allele
Sp140l2<+> | MGI:3793270
 
Name: Sp140 nuclear body protein like 2; wild type
Allele Type: Not Specified
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Allele
Sp140l2<tm1(KOMP)Vlcg> | MGI:4460614
Name: Sp140 nuclear body protein like 2; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Sp140l1<+> | MGI:5479056
 
Name: Sp140 nuclear body protein like 1; wild type
Allele Type: Not Specified
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Allele
Sp140<tm1.1Ptsn> | MGI:6342926
Name: Sp140 nuclear body protein; targeted mutation 1.1, Part Peterson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Sp140<em1Vnce> | MGI:7386886
Name: Sp140 nuclear body protein; endonuclease-mediated mutation 1, Russell Vance
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGP_AKRJ_G0016173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3612702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3037746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016075 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:6335840 | B6;129S6-Sp140<tm1Ptsn>/Kctt
Attribute String: mutant strain, targeted mutation
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Strain
MGI:7709175 | C57BL/6J-Sp140<em1Vnce>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Sp140<em1Smoc> | MGI:7766708
Name: Sp140 nuclear body protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Sp140/Sp140
Background: C57BL/6J-Sp140
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7767712 | C57BL/6JSmoc-Sp140<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Ifnar1/Ifnar1 Sp140/Sp140
Background: B6.Cg-Sp140 Ifnar1
Zygosity: cx
Has Mutant Allele: true
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GO Term
GO:0030577 | Lands organization
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Protein
Q8C308
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: false
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Publication
16803959 | -
First Author: Tosh K
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.
Volume: 103
Issue: 27
Pages: 10364-10368
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Publication
21222611 | -
First Author: Cai L
Year: 2011
Journal: Med Chem
Title: Identification of proteins interacting with human SP110 during the process of viral infections.
Volume: 7
Issue: 2
Pages: 121-6
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Publication
10913195 | -
First Author: Bloch DB
Year: 2000
Journal: Mol Cell Biol
Title: Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator.
Volume: 20
Issue: 16
Pages: 6138-46
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Publication
16648851 | -
First Author: Roscioli T
Year: 2006
Journal: Nat Genet
Title: Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease.
Volume: 38
Issue: 6
Pages: 620-2
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Protein Domain
IPR043563 | Sp110/Sp140/Sp140L
Type: Family
Description: This entry includes a group of nuclear dot-associated proteins, including Sp110/Sp140/Sp140L from humans. They are proteins with a constituent of nuclear domains, also known as nuclear dots (NDs). Sequences similar to the Sp100 homodimerization/ND-targeting region occur in several other proteins and constitute a novel protein motif, termed HSR domain (for homogeneously-staining region) [].Sp110 is a leukocyte-specific component of the nuclear body []. It may function as a nuclear hormone receptor transcriptional coactivator that may play a role in inducing differentiation of myeloid cells []. It is also involved in resisting intracellular pathogens and functions as an important drug target for preventing intracellular pathogen diseases, such as tuberculosis, hepatic veno-occlusive disease, and intracellular cancers [, ]. Sp110 gene polymorphisms may be associated with susceptibility to tuberculosis in Chinese population []. The function of nuclear protein Sp140 is not known, though it contains several chromatin related modules such as plant homeodomain (PHD), bromodomain (BRD) and SAND domain, which suggests a role in chromatin-mediated regulation of gene expression []. It also harbours a nuclear localisation signal and a dimerisation domain (HSR or CARD domain). The PHD finger of Sp140 presents an atypical fold which does not bind to histone H3 tails but binds to peptidylprolyl isomerase Pin1. Pin1 catalyses the isomerisation of a phospho-Threonine-Proline bond in Sp140-PHD and thus may modulate Sp140 function [].Human Sp140 is an interferon inducible nuclear leukocyte-specific protein that may be involved in the pathogenesis of acute promyelocytic leukemia and viral infection []. It localises to LYSP100-associated nuclear dots and is also a component of the promyelocytic leukemia nuclear body (PML-NBs) [, ]. The Sp140 locus has been identified as a lymphocytic leukemia (CLL) risk locus [].This family also includes protein Sp140-like (SP140L) [].
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Protein
Q99388
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein
E0CXN9
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Protein
Q3UTB2
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
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Protein
Q3TQS4
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
Q3TZR7
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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Protein
E9PV05
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Protein
E9Q422
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q4KKY3
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: false
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Protein
E9Q4Y0
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q52KL8
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: false
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Protein
E9Q3M7
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Protein
Q8BNW8
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: true
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Protein
Q8BS13
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Protein
Q8C9H3
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q3UT50
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: false
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Protein
Q7TSS9
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
D6RIJ4
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
E0CXL1
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: false
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Protein
Q3UKD8
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
E0CY74
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
Q3KNJ6
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
Q8C9T1
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
Q8C898
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
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Publication
10212234 | -
First Author: Sternsdorf T
Year: 1999
Journal: J Biol Chem
Title: The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers.
Volume: 274
Issue: 18
Pages: 12555-66
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Publication
28783698 | J:259781
 
First Author: Mehta S
Year: 2017
Journal: Sci Immunol
Title: Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140.
Volume: 2
Issue: 9
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Protein
O35892
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Protein
Q8BVK9
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
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Protein
Q3U876
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
Q6NTA3
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
A0A1B0GX24
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: true
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Protein
A0A1B0GT08
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: true
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Protein
E9QA05
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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