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Search results 101 to 173 out of 173 for Stim2

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Type Details Score
Publication
28132808 | J:256618
First Author: Maus M
Year: 2017
Journal: Cell Metab
Title: Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism.
Volume: 25
Issue: 3
Pages: 698-712
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Publication
25471906 | J:219359
First Author: Michaelis M
Year: 2015
Journal: Glia
Title: STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.
Volume: 63
Issue: 4
Pages: 652-63
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Publication
21746875 | J:175075
First Author: Zeiger W
Year: 2011
Journal: Mol Cell Biol
Title: Stanniocalcin 2 is a negative modulator of store-operated calcium entry.
Volume: 31
Issue: 18
Pages: 3710-22
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Publication
26522985 | J:234444
First Author: McDonald BD
Year: 2015
Journal: Immunity
Title: Crossreactive αβ T Cell Receptors Are the Predominant Targets of Thymocyte Negative Selection.
Volume: 43
Issue: 5
Pages: 859-69
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Publication
28294127 | J:241365
 
First Author: Vaeth M
Year: 2017
Journal: Nat Commun
Title: ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.
Volume: 8
Pages: 14714
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Publication
38467629 | J:360918
First Author: Xu M
Year: 2024
Journal: Nat Commun
Title: The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
Volume: 15
Issue: 1
Pages: 2194
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Publication
32294437 | J:323545
First Author: Berry CT
Year: 2020
Journal: Cell Rep
Title: BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells.
Volume: 31
Issue: 2
Pages: 107474
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Publication
29030115 | J:259234
First Author: Vaeth M
Year: 2017
Journal: Immunity
Title: Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.
Volume: 47
Issue: 4
Pages: 664-679.e6
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Publication
35105987 | J:333844
First Author: Concepcion AR
Year: 2022
Journal: Nat Immunol
Title: The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Volume: 23
Issue: 2
Pages: 287-302
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Publication
34047696 | J:308492
   
First Author: Lebratti T
Year: 2021
Journal: Elife
Title: A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection.
Volume: 10
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Publication
38878778 | J:350991
First Author: Woo MS
Year: 2024
Journal: Cell
Title: STING orchestrates the neuronal inflammatory stress response in multiple sclerosis.
Volume: 187
Issue: 15
Pages: 4043-4060.e30
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Publication
30563862 | J:284476
 
First Author: Diercks BP
Year: 2018
Journal: Sci Signal
Title: ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Volume: 11
Issue: 561
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Publication
25737585 | J:259457
First Author: Shanmughapriya S
Year: 2015
Journal: Sci Signal
Title: Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Volume: 8
Issue: 366
Pages: ra23
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Publication
22411552 | J:181604
First Author: Seth M
Year: 2012
Journal: Dev Dyn
Title: Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.
Volume: 241
Issue: 4
Pages: 639-47
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26300487 | J:231406
First Author: Rao W
Year: 2015
Journal: Biochim Biophys Acta
Title: Downregulation of STIM2 improves neuronal survival after traumatic brain injury by alleviating calcium overload and mitochondrial dysfunction.
Volume: 1852
Issue: 11
Pages: 2402-13
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Publication
26033257 | J:227140
First Author: Rana A
Year: 2015
Journal: J Cell Biol
Title: Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels.
Volume: 209
Issue: 5
Pages: 653-69
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Publication
19019825 | -
First Author: Stathopulos PB
Year: 2009
Journal: J Biol Chem
Title: Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics.
Volume: 284
Issue: 2
Pages: 728-32
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Publication
18166150 | -
First Author: Zheng L
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2.
Volume: 369
Issue: 1
Pages: 240-6
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Protein Domain
IPR037608 | STIM
Type: Family
Description: STIM proteins contain a single SAM (sterile alpha-motif) domain and an unpaired EF hand within the highly conserved extracellular region, and the coiled-coil domains thatare conserved in structure and position within the cytoplasmic region []. The EF-hand and SAM domain of the STIM proteins serves as a Ca2+ sensory region []. "Hidden"EF hand and SAM domains have a stable intramolecular association. Destabilization of the EF-SAM association during Ca2+ depletion leads to partial unfolding and aggregation (homooligomerization) []. STIM oligomerization is a key induction step in the activation of Ca(2+)-permeable channels on the plasma membrane. In human cells, STIM1 and STIM2 are regulators of store-operated calcium (Ca(2+)) entry as well as basal cytoplasmic Ca(2+) levels [].
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Protein Domain
IPR037610 | STIM2_SAM
Type: Domain
Description: STIM proteins contain a single SAM (sterile alpha-motif) domain and an unpaired EF hand within the highly conserved extracellular region, and the coiled-coil domains that are conserved in structure and position within the cytoplasmic region []. The EF-hand and SAM domain of the STIM proteins serves as a Ca2+ sensory region []. "Hidden"EF hand and SAM domains have a stable intramolecular association. Destabilization of the EF-SAM association during Ca2+ depletion leads to partial unfolding and aggregation (homooligomerization) []. STIM oligomerization is a key induction step in the activation of Ca(2+)-permeable channels on the plasma membrane. In human cells, STIM1 and STIM2 are regulators of store-operated calcium (Ca(2+)) entry as well as basal cytoplasmic Ca(2+) levels [].This entry represents the SAM domain of STIM2.
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Publication
20887894 | J:167918
First Author: Feng M
Year: 2010
Journal: Cell
Title: Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Volume: 143
Issue: 1
Pages: 84-98
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Publication
18854159 | -
First Author: Stathopulos PB
Year: 2008
Journal: Cell
Title: Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Volume: 135
Issue: 1
Pages: 110-22
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Protein
Q8BIM2
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: true
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Protein
F6WBP9
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: true
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Protein
A0A1B0GQZ3
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
Q3TUX9
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Publication
29247211 | J:323751
First Author: Pchitskaya E
Year: 2017
Journal: Sci Rep
Title: Stim2-Eb3 Association and Morphology of Dendritic Spines in Hippocampal Neurons.
Volume: 7
Issue: 1
Pages: 17625
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Publication
24523925 | J:212945
First Author: Schmid E
Year: 2014
Journal: PLoS One
Title: Decreased store operated Ca2+ entry in dendritic cells isolated from mice expressing PKB/SGK-resistant GSK3.
Volume: 9
Issue: 2
Pages: e88637
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Publication
26424877 | J:226473
First Author: Zhang H
Year: 2015
Journal: J Neurosci
Title: Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.
Volume: 35
Issue: 39
Pages: 13275-86
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Publication
23171960 | J:318155
First Author: Schmid E
Year: 2012
Journal: Cell Physiol Biochem
Title: SGK3 regulates Ca(2+) entry and migration of dendritic cells.
Volume: 30
Issue: 6
Pages: 1423-35
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Protein
P83093
Organism: Mus musculus/domesticus
Length: 746  
Fragment?: false
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Protein
A5CVE4
Organism: Mus musculus/domesticus
Length: 746  
Fragment?: false
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Protein
Q8C4Z8
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
I1E4X8
Organism: Mus musculus/domesticus
Length: 754  
Fragment?: false
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Publication
26985029 | J:231658
First Author: Molnár T
Year: 2016
Journal: J Neurosci
Title: Store-Operated Calcium Entry in Müller Glia Is Controlled by Synergistic Activation of TRPC and Orai Channels.
Volume: 36
Issue: 11
Pages: 3184-98
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Protein
P70302
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
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Protein
A0A1B0GR78
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
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Protein
A0A1B0GRA5
Organism: Mus musculus/domesticus
Length: 793  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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