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Search results 101 to 190 out of 190 for Tacc1

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0.024s
Type Details Score
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1620421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 14
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1620421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 3D
Note: Expression is particularly strong in the adventitia and endothelium.
Specimen Label: 3D
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634616
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:3629200
Age: embryonic day 10.0
Image: 3B
Note: Expression is in the epithelial layers.
Specimen Label: 3B
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1634621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 14
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1683424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3629200
Age: embryonic day 16.0
Image: 4H
Note: Staining is nuclear in the muscle cells of the muscularis propria.
Specimen Label: 4H
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611716
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3629200
Age: embryonic day 10.0
Image: 1A
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3629200
Age: embryonic day 11.0
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3629200
Age: embryonic day 11.0
Image: 4A
Specimen Label: 4A
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1715218
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3629200
Age: embryonic day 11.0
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3267918
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3629200
Age: embryonic day 11.0
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619114
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:3629200
Age: embryonic day 9.0
Image: 2A,B
Specimen Label: 2A,B
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608914
Pattern: Graded
Stage: TS14
Assay Id: MGI:3629200
Age: embryonic day 9.0
Image: 2A,B
Note: The ependymal layer and alar plate exhibit the highest staining with decreasing expression toward the mantle layer.
Specimen Label: 2A,B
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3629200
Age: embryonic day 12.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 1D
Note: The highest expression is maintained in actively dividing tissues and neuronal progenitors prior to terminal differentiation.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3629200
Age: embryonic day 14.0
Image: 1E
Note: The highest expression is maintained in actively dividing tissues and neuronal progenitors prior to terminal differentiation.
Specimen Label: 1E
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3629200
Age: embryonic day 16.0
Image: 4I
Note: Staining is cytoplasmic.
Specimen Label: 4I
Detected: true
Specimen Num: 23
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1701524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3629200
Age: embryonic day 16.0
Image: 3E,F,G
Note: Expression is particularly strong in the adventitia and endothelium.
Specimen Label: 3E,F,G
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3629200
Age: embryonic day 12.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 1D
Note: The highest expression is maintained in actively dividing tissues and neuronal progenitors prior to terminal differentiation.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3629200
Age: embryonic day 14.0
Image: 1E
Note: The highest expression is maintained in actively dividing tissues and neuronal progenitors prior to terminal differentiation.
Specimen Label: 1E
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3629200
Age: embryonic day 12.0
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3629200
Age: embryonic day 13.0
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:3629195
Assay Type: Immunohistochemistry
Annotation Date: 2006-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3629200
Age: embryonic day 14.0
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 5
Publication
First Author: Wilde JJ
Year: 2017
Journal: J Neurosci
Title: Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.
Volume: 37
Issue: 10
Pages: 2565-2579
Publication
First Author: Schuendeln MM
Year: 2004
Journal: Mol Cell Biol
Title: The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer.
Volume: 24
Issue: 14
Pages: 6403-9
Publication  
First Author: Still IH
Year: 2004
Journal: BMC Evol Biol
Title: Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
Volume: 4
Pages: 16
Publication
First Author: Xie Z
Year: 2007
Journal: Neuron
Title: Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.
Volume: 56
Issue: 1
Pages: 79-93
Publication
First Author: Hemberger M
Year: 2000
Journal: Dev Biol
Title: cDNA subtraction cloning reveals novel genes whose temporal and spatial expression indicates association with trophoblast invasion.
Volume: 222
Issue: 1
Pages: 158-69
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Gergely F
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.
Volume: 97
Issue: 26
Pages: 14352-7
Publication  
First Author: Mortuza GB
Year: 2014
Journal: Nat Commun
Title: XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.
Volume: 5
Pages: 5072
Protein Domain
Type: Domain
Description: This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organising centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1) []. TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis []. Maskin is also found to bind CPEB and elF-4E []. Interestingly, the functional homologue (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organisation of bipolar spindles [].
Publication
First Author: Still IH
Year: 1999
Journal: Genomics
Title: The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines.
Volume: 58
Issue: 2
Pages: 165-70
Publication
First Author: Cully M
Year: 2005
Journal: Cancer Res
Title: Transforming acidic coiled coil 1 promotes transformation and mammary tumorigenesis.
Volume: 65
Issue: 22
Pages: 10363-70
Publication
First Author: Long MD
Year: 2019
Journal: Oncogene
Title: The miR-96 and RARγ signaling axis governs androgen signaling and prostate cancer progression.
Volume: 38
Issue: 3
Pages: 421-444
Protein
Organism: Mus musculus/domesticus
Length: 1149  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 630  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2879  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 829  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1020  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1146  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 696  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1033  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1036  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 630  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 637  
Fragment?: false
Publication
First Author: Sato M
Year: 2004
Journal: Mol Biol Cell
Title: Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.
Volume: 15
Issue: 4
Pages: 1609-22
Publication
First Author: Stebbins-Boaz B
Year: 1999
Journal: Mol Cell
Title: Maskin is a CPEB-associated factor that transiently interacts with elF-4E.
Volume: 4
Issue: 6
Pages: 1017-27