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Search results 101 to 200 out of 206 for Taf12

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13004
Specimen Label: GUDMAP:13004
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13004
Specimen Label: GUDMAP:13004
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13004
Specimen Label: GUDMAP:13004
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
•
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13004
Specimen Label: GUDMAP:13004
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002160
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542714
Age: embryonic day 15.5
Image: GUDMAP:13005
Specimen Label: GUDMAP:13005
Detected: false
Specimen Num: 2
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Publication
16481476 | J:105720
First Author: Frock RL
Year: 2006
Journal: Genes Dev
Title: Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation.
Volume: 20
Issue: 4
Pages: 486-500
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Publication
17694077 | J:320276
First Author: Nagy Z
Year: 2007
Journal: Oncogene
Title: Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.
Volume: 26
Issue: 37
Pages: 5341-57
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Publication
9880483 | J:320278
First Author: Schiltz RL
Year: 1999
Journal: J Biol Chem
Title: Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates.
Volume: 274
Issue: 3
Pages: 1189-92
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Publication
14580349 | J:86236
First Author: Guermah M
Year: 2003
Journal: Mol Cell
Title: The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.
Volume: 12
Issue: 4
Pages: 991-1001
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Publication
11564863 | J:320036
First Author: Martinez E
Year: 2001
Journal: Mol Cell Biol
Title: Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Volume: 21
Issue: 20
Pages: 6782-95
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Publication
19114550 | J:320037
First Author: Nagy Z
Year: 2009
Journal: Mol Cell Biol
Title: The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.
Volume: 29
Issue: 6
Pages: 1649-60
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Publication
11406595 | J:320001
First Author: Brand M
Year: 2001
Journal: EMBO J
Title: UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Volume: 20
Issue: 12
Pages: 3187-96
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Publication
10373431 | J:320038
First Author: Brand M
Year: 1999
Journal: J Biol Chem
Title: Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.
Volume: 274
Issue: 26
Pages: 18285-9
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Publication
19103755 | J:145720
First Author: Guelman S
Year: 2009
Journal: Mol Cell Biol
Title: The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Volume: 29
Issue: 5
Pages: 1176-88
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Publication
18206972 | J:320111
First Author: Zhao Y
Year: 2008
Journal: Mol Cell
Title: A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 92-101
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Publication
- | J:279207
     
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
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Publication
25209997 | J:228779
 
First Author: Alpern D
Year: 2014
Journal: Elife
Title: TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Volume: 3
Pages: e03613
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Publication
18722179 | J:138818
First Author: Tatarakis A
Year: 2008
Journal: Mol Cell
Title: Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
Volume: 31
Issue: 4
Pages: 531-43
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Publication
35361962 | J:337771
First Author: El-Saafin F
Year: 2022
Journal: Cell Death Differ
Title: Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
Volume: 29
Issue: 5
Pages: 1013-1027
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Publication
28893950 | J:245730
First Author: Bardot P
Year: 2017
Journal: Development
Title: The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
Volume: 144
Issue: 20
Pages: 3808-3818
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Publication
27026076 | J:236825
 
First Author: Langer D
Year: 2016
Journal: Nat Commun
Title: Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.
Volume: 7
Pages: 11063
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Publication
22323595 | J:181994
First Author: Kamileri I
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.
Volume: 109
Issue: 8
Pages: 2995-3000
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19217408 | J:146620
First Author: Schmitz KM
Year: 2009
Journal: Mol Cell
Title: TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.
Volume: 33
Issue: 3
Pages: 344-53
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GXD Expression
GXD Expression
   
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641361
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641361
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641361
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7641292
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641361
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641367
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641367
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641367
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7641291
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641367
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641368
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641368
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641368
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7641290
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7641368
Age: embryonic day 3.5
Image: 1
Specimen Label: Taf12 +/-
Detected: true
Specimen Num: 4
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Gene
608297 | LOC608297
Type: gene
Organism: dog, domestic
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Publication
19635797 | -
First Author: Gazit K
Year: 2009
Journal: J Biol Chem
Title: TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
Volume: 284
Issue: 39
Pages: 26286-96
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Allele
Taf12<em1(IMPC)Mbp> | MGI:6276947
Name: TATA-box binding protein associated factor 12; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6348052 | C57BL/6NCrl-Taf12<em1(IMPC)Mbp>/Mmucd
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Taf12/Taf12
Background: C57BL/6NCrl-Taf12/Mmucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Taf12/Taf12<+>
Background: C57BL/6NCrl-Taf12/Mmucd
Zygosity: ht
Has Mutant Allele: true
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Publication
22426530 | -
First Author: Spedale G
Year: 2012
Journal: Genes Dev
Title: ATAC-king the complexity of SAGA during evolution.
Volume: 26
Issue: 6
Pages: 527-41
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Protein Domain
IPR039460 | SUPT7L
Type: Family
Description: STAGA complex 65 subunit gamma (SUPT7L) is a component of the structural core of the STAGA transcription coactivator-histone acetyltransferase (HAT) complex, which is composed of at least SUPT3H, SUPT7L, GCN5L2, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12 and TAF9. This complex, the TAF8-TAF10 histone fold (HF)-containing protein complex and the SMAT complex are important regulators of the composition of different TFIID and/or STAGA/TFTC complexes in the nucleus and consequently may play a role in gene regulation [, ].
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Publication
25965574 | J:221400
First Author: Tong Y
Year: 2015
Journal: Cancer Cell
Title: Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes.
Volume: 27
Issue: 5
Pages: 712-27
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Publication
29316427 | J:253748
First Author: Xu Y
Year: 2018
Journal: Cancer Cell
Title: A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia.
Volume: 33
Issue: 1
Pages: 13-28.e8
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Protein Domain
IPR007900 | TAF4_C
Type: Domain
Description: Accurate transcription initiation at protein-coding genes by RNA polymerase II requires the assembly of amultiprotein complex around the mRNA start site. Transcription factor TFIID is one of the general factors involved in this process. Yeast TFIID comprises the TATA binding protein and 14 TBP-associated factors (TAFIIs), nine of which contain histone-fold domains. The C-terminal region of the TFIID-specific yeast TAF4 (yTAF4) containing the HFD shares strong sequence similarity with Drosophila (d)TAF4 and human TAF4. A structure/function analysis of yTAF4 demonstrates that the HFD, a short conserved C-terminal domain (CCTD), and the region separating them are all required for yTAF4 function. This region of similarity is found in Transcription initiation factor TFIID component TAF4 []. TAF4 domain interacts with TAF12 and makes a novel histone-like heterodimer that binds DNA and has a core promoter function of a subset of genes [, , ].
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Protein Domain
IPR003228 | TFIID_TAF12_dom
Type: Domain
Description: TFIID is one of several General Transcription Factors (GTFs), which also include TFIIA, TFIIB, TFIIE, TFIIF and TFIIH, that are involved in the accurate initiation of transcription by RNA polymerase II in eukaryotes. TFIID plays an important role in the recognition of promoter DNA and assembly of the pre-initiation complex. Human transcription initiation factor TFIID is composed of the TATA-binding protein (TBP) and at least 13 TBP-associated factors (TAFs) that collectively or individually are involved in activator-dependent transcription [, ].TBP-associated factor 12 (TAF12) is one of several TAFs that bind TBP and are involved in forming the TFIID complex. TAF12 interacts with TAF4 and makes a novel histone-like heterodimer that binds DNA and has a core promoter function of a subset of genes [].This entry represents a domain found in TAF12.
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Publication
22454401 | J:210503
First Author: Heiliger KJ
Year: 2012
Journal: Endocr Relat Cancer
Title: Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.
Volume: 19
Issue: 3
Pages: 409-21
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Publication
23794264 | J:315252
First Author: Sun Q
Year: 2014
Journal: J Bone Miner Res
Title: TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
Volume: 29
Issue: 1
Pages: 90-102
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Protein
Q8C0S6
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Publication
12237303 | -
First Author: Thuault S
Year: 2002
Journal: J Biol Chem
Title: Functional analysis of the TFIID-specific yeast TAF4 (yTAF(II)48) reveals an unexpected organization of its histone-fold domain.
Volume: 277
Issue: 47
Pages: 45510-7
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Publication
30442764 | -
 
First Author: Patel AB
Year: 2018
Journal: Science
Title: Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Volume: 362
Issue: 6421
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Protein
Q9CZV5
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
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Protein
D3Z6Y8
Organism: Mus musculus/domesticus
Length: 363  
Fragment?: false
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Protein
Q8BXI0
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q3UMC6
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
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Protein
E9PX66
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Publication
7667268 | -
First Author: Hisatake K
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.
Volume: 92
Issue: 18
Pages: 8195-9
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Publication
17375202 | -
First Author: Demény MA
Year: 2007
Journal: PLoS One
Title: Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.
Volume: 2
Issue: 3
Pages: e316
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Protein
G5E8Z2
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
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