| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:4417250 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824738 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011592_24 |
|
| Specimen Label: |
euxassay_011592_24 |
| Detected: |
true |
| Specimen Num: |
24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park MY |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
FAM19A5, a brain-specific chemokine, inhibits RANKL-induced osteoclast formation through formyl peptide receptor 2. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
15575 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kwak H |
| Year: |
2024 |
| Journal: |
Mol Cells |
| Title: |
Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knockout, and LacZ knockin mice. |
| Volume: |
47 |
| Issue: |
12 |
| Pages: |
100125 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramalingam H |
| Year: |
2018 |
| Journal: |
Dev Biol |
| Title: |
Disparate levels of beta-catenin activity determine nephron progenitor cell fate. |
| Volume: |
440 |
| Issue: |
1 |
| Pages: |
13-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang S |
| Year: |
2021 |
| Journal: |
Mol Psychiatry |
| Title: |
FAM19A5/TAFA5, a novel neurokine, plays a crucial role in depressive-like and spatial memory-related behaviors in mice. |
| Volume: |
26 |
| Issue: |
6 |
| Pages: |
2363-2379 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shahapal A |
| Year: |
2019 |
| Journal: |
Front Neurosci |
| Title: |
FAM19A5 Expression During Embryogenesis and in the Adult Traumatic Brain of FAM19A5-LacZ Knock-in Mice. |
| Volume: |
13 |
|
| Pages: |
917 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pan X |
| Year: |
2017 |
| Journal: |
Development |
| Title: |
Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells. |
| Volume: |
144 |
| Issue: |
22 |
| Pages: |
4173-4182 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karner CM |
| Year: |
2011 |
| Journal: |
Development |
| Title: |
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. |
| Volume: |
138 |
| Issue: |
7 |
| Pages: |
1247-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Das A |
| Year: |
2013 |
| Journal: |
Nat Cell Biol |
| Title: |
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. |
| Volume: |
15 |
| Issue: |
9 |
| Pages: |
1035-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vidal VP |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boivin FJ |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0120347 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takasato M |
| Year: |
2004 |
| Journal: |
Mech Dev |
| Title: |
Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. |
| Volume: |
121 |
| Issue: |
6 |
| Pages: |
547-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
TAFA chemokine like family member 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
133
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
2018 |
| Journal: |
Acta Biochim Biophys Sin (Shanghai) |
| Title: |
Tafa-2 plays an essential role in neuronal survival and neurobiological function in mice. |
| Volume: |
50 |
| Issue: |
10 |
| Pages: |
984-995 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
132
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
135
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
135
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This family is composed of five highly homologous small secreted proteins, TAFA1-5. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The FAM19/TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells []. Mouse TAFA2 is involved in neuronal survival and neurobiological functions []. TAFA5 has been shown to inhibit postinjury neointima formation via sphingosine-1-phosphate receptor 2-G12/13-RhoA signaling []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
132
 |
| Fragment?: |
false |
|
•
•
•
•
•
|