Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:4417250 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824738 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011592_24 |
|
Specimen Label: |
euxassay_011592_24 |
Detected: |
true |
Specimen Num: |
24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park MY |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
FAM19A5, a brain-specific chemokine, inhibits RANKL-induced osteoclast formation through formyl peptide receptor 2. |
Volume: |
7 |
Issue: |
1 |
Pages: |
15575 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kwak H |
Year: |
2024 |
Journal: |
Mol Cells |
Title: |
Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knockout, and LacZ knockin mice. |
Volume: |
47 |
Issue: |
12 |
Pages: |
100125 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramalingam H |
Year: |
2018 |
Journal: |
Dev Biol |
Title: |
Disparate levels of beta-catenin activity determine nephron progenitor cell fate. |
Volume: |
440 |
Issue: |
1 |
Pages: |
13-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang S |
Year: |
2021 |
Journal: |
Mol Psychiatry |
Title: |
FAM19A5/TAFA5, a novel neurokine, plays a crucial role in depressive-like and spatial memory-related behaviors in mice. |
Volume: |
26 |
Issue: |
6 |
Pages: |
2363-2379 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shahapal A |
Year: |
2019 |
Journal: |
Front Neurosci |
Title: |
FAM19A5 Expression During Embryogenesis and in the Adult Traumatic Brain of FAM19A5-LacZ Knock-in Mice. |
Volume: |
13 |
|
Pages: |
917 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pan X |
Year: |
2017 |
Journal: |
Development |
Title: |
Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells. |
Volume: |
144 |
Issue: |
22 |
Pages: |
4173-4182 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karner CM |
Year: |
2011 |
Journal: |
Development |
Title: |
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. |
Volume: |
138 |
Issue: |
7 |
Pages: |
1247-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das A |
Year: |
2013 |
Journal: |
Nat Cell Biol |
Title: |
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. |
Volume: |
15 |
Issue: |
9 |
Pages: |
1035-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vidal VP |
Year: |
2020 |
Journal: |
Elife |
Title: |
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Boivin FJ |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium. |
Volume: |
10 |
Issue: |
3 |
Pages: |
e0120347 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takasato M |
Year: |
2004 |
Journal: |
Mech Dev |
Title: |
Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. |
Volume: |
121 |
Issue: |
6 |
Pages: |
547-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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|
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•
•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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|
|
|
•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
Allele |
Name: |
TAFA chemokine like family member 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2018 |
Journal: |
Acta Biochim Biophys Sin (Shanghai) |
Title: |
Tafa-2 plays an essential role in neuronal survival and neurobiological function in mice. |
Volume: |
50 |
Issue: |
10 |
Pages: |
984-995 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
132
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
135
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
135
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This family is composed of five highly homologous small secreted proteins, TAFA1-5. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The FAM19/TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells []. Mouse TAFA2 is involved in neuronal survival and neurobiological functions []. TAFA5 has been shown to inhibit postinjury neointima formation via sphingosine-1-phosphate receptor 2-G12/13-RhoA signaling []. |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
132
 |
Fragment?: |
false |
|
•
•
•
•
•
|