Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 113 out of 113 for Tax1bp1

<< First < Previous | Next > Last >>

0.017s

Type

Details

Score

Publication

27062441 | J:248713

First Author:	Suzuki N
Year:	2016
Journal:	FEBS J
Title:	A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
Volume:	283
Issue:	11
Pages:	2004-17

•

Publication

25774694 | J:245506

First Author:	Pujari R
Year:	2015
Journal:	PLoS Pathog
Title:	Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.
Volume:	11
Issue:	3
Pages:	e1004721

•

Publication

14755250 | -

First Author:	Li H
Year:	2004
Journal:	Oncogene
Title:	An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.
Volume:	23
Issue:	10
Pages:	1801-8

•

Publication

19262463 | -

First Author:	Jacque E
Year:	2009
Journal:	EMBO J
Title:	RNF11, a new piece in the A20 puzzle.
Volume:	28
Issue:	5
Pages:	455-6

•

Publication

23222715 | -

First Author:	Kostaras E
Year:	2013
Journal:	Oncogene
Title:	SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.
Volume:	32
Issue:	44
Pages:	5220-32

•

Publication

25195858 | -

First Author:	Santonico E
Year:	2015
Journal:	Oncogene
Title:	RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.
Volume:	34
Issue:	26
Pages:	3377-90

•

Publication

14559117 | -

First Author:	Kitching R
Year:	2003
Journal:	Biochim Biophys Acta
Title:	The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases.
Volume:	1639
Issue:	2
Pages:	104-12

•

Publication

14562029 | -

First Author:	Subramaniam V
Year:	2003
Journal:	Br J Cancer
Title:	The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.
Volume:	89
Issue:	8
Pages:	1538-44

•

Publication

19528490 | -

First Author:	Azmi PB
Year:	2009
Journal:	Anticancer Res
Title:	The RING finger protein11 binds to Smad4 and enhances Smad4-dependant TGF-beta signalling.
Volume:	29
Issue:	6
Pages:	2253-63

•

Protein Domain

IPR042981 | RNF11_RING-H2

Type:

Domain

Description:

RING finger protein 11 (RNF11) is an E3 ubiquitin-protein ligase that acts both as an adaptor and a modulator of itch-mediated control of ubiquitination events underlying membrane traffic. It is the downstream of an enzymatic cascade for the ubiquitination of specific substrates. It is also a molecular adaptor of homologous to E6-associated protein C terminus (HECT)-type ligases []. RNF11 has been implicated in the regulation of several signaling pathways. It enhances the transforming growth factor receptor (TGFR) signaling by both abrogating Smurf2-mediated receptor ubiquitination and by promoting the Smurf2-mediated degradation of AMSH (associated molecule with the SH3 domain of STAM), a de-ubiquitinating enzyme that enhances transforming growth factor-beta (TGF-beta) signalling and epidermal growth factor receptor (EGFR) endosomal recycling [, ]. It also acts directly on Smad4 to enhance Smad4 function, and plays a role in prolonged TGF-beta signalling []. Moreover, RNF11 functions as a critical component of the A20 ubiquitin-editing protein complex that negatively regulates tumor necrosis factor (TNF)-mediated nuclear factor (NF)-kappaB activation []. It also interacts with Smad anchor for receptor activation (SARA) and the endosomal sorting complex required for transport (ESCRT)-0 complex, thus participating in the regulation of lysosomal degradation of EGFR []. Furthermore, RNF11 acts as a novel GGA cargo actively participating in regulating the ubiquitination of the GGA protein family []. In addition, RNF11 functions together with TAX1BP1 to target TANK-binding kinase 1 (TBK1)/IkappaB kinase IKKi, and further restricts antiviral signaling and type I interferon (IFN)-beta production []. RNF11 contains an N-terminal PPPY motif that binds WW domain-containing proteins such as AIP4/itch, Nedd4 and Smurf1/2 (SMAD-specific E3 ubiquitin-protein ligase 1/2), and a C-terminal C3H2C3-type RING-H2 finger that functions as a scaffold for the coordinated transfer of ubiquitin to substrate proteins together with the E2 enzymes UbcH527 and Ubc13.

•

Publication

30290707 | J:310931

First Author:	Xu Y
Year:	2019
Journal:	Autophagy
Title:	The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Volume:	15
Issue:	4
Pages:	583-598

•

Protein

Q9QYK7

Organism:	Mus musculus/domesticus
Length:	154
Fragment?:	false

•

Protein

Z4YLT8

Organism:	Mus musculus/domesticus
Length:	144
Fragment?:	true

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=100&searchTerm=Tax1bp1

MouseMine

Search our database by keyword

Examples

Search results 101 to 113 out of 113 for Tax1bp1

Categories

Hits by Pathway

Hits by Category

Hits by Strain