Type |
Details |
Score |
Publication |
First Author: |
Yang Z |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. |
Volume: |
45 |
Issue: |
1 |
Pages: |
123-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brinkmeier ML |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs. |
Volume: |
43 |
Issue: |
1 |
Pages: |
9-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaput J |
Year: |
2004 |
Journal: |
Physiol Genomics |
Title: |
Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions. |
Volume: |
18 |
Issue: |
3 |
Pages: |
316-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gineste C |
Year: |
2013 |
Journal: |
Neuromuscul Disord |
Title: |
In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. |
Volume: |
23 |
Issue: |
4 |
Pages: |
357-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Welch CL |
Year: |
1996 |
Journal: |
J Lipid Res |
Title: |
Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. |
Volume: |
37 |
Issue: |
7 |
Pages: |
1406-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo G |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
Volume: |
18 |
Issue: |
4 |
Pages: |
675-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Publication |
First Author: |
Jacquemin P |
Year: |
1998 |
Journal: |
Dev Dyn |
Title: |
Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro. |
Volume: |
212 |
Issue: |
3 |
Pages: |
423-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hunger SP |
Year: |
1996 |
Journal: |
Blood |
Title: |
The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties. |
Volume: |
87 |
Issue: |
11 |
Pages: |
4607-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Braun F |
Year: |
2019 |
Journal: |
Microbiologyopen |
Title: |
Cyclic nucleotides in archaea: Cyclic di-AMP in the archaeon Haloferax volcanii and its putative role. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e00829 |
|
•
•
•
•
•
|
Allele |
Name: |
thyrotroph embryonic factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Vaudin P |
Year: |
1999 |
Journal: |
Development |
Title: |
TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation. |
Volume: |
126 |
Issue: |
21 |
Pages: |
4807-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fonjallaz P |
Year: |
1996 |
Journal: |
EMBO J |
Title: |
The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences. |
Volume: |
15 |
Issue: |
2 |
Pages: |
351-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inaba T |
Year: |
1992 |
Journal: |
Science |
Title: |
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. |
Volume: |
257 |
Issue: |
5069 |
Pages: |
531-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burch JB |
Year: |
1994 |
Journal: |
Nucleic Acids Res |
Title: |
Alternative promoter usage and splicing options result in the differential expression of mRNAs encoding four isoforms of chicken VBP, a member of the PAR subfamily of bZIP transcription factors. |
Volume: |
22 |
Issue: |
22 |
Pages: |
4733-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iyer SV |
Year: |
1991 |
Journal: |
Mol Cell Biol |
Title: |
Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP. |
Volume: |
11 |
Issue: |
10 |
Pages: |
4863-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benito A |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. |
Volume: |
281 |
Issue: |
50 |
Pages: |
38351-7 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Thyrotroph embryonic factor (TEF) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. TEF may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It binds to the consensus sequence 5'-GTTACGTAAT-3' []. TEF is involved in the regulation of apoptotic proteins [, ]. In chicken it is known as VBP, which binds to and transactivates the vitellogenin II (VTG2) promoter [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Shutler G |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Genomic structure of the human D-site binding protein (DBP) gene. |
Volume: |
34 |
Issue: |
3 |
Pages: |
334-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Repeat |
Description: |
The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses aTEA/ATTS DNA-binding domain. Transcriptional activation by these proteins likely requires interactions with specific coactivators. InDrosophila, Scalloped (Sd) interacts with Vestigial (Vg) to form a complex, which binds DNA through the Sd TEA/ATTS domain.The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wingoutgrowth when ectopically expressed. The human protein, TONDU, contains a short domain homologous to the domain of Vg required for interaction withSd. TONDU specifically interacts with a domain conserved in all the mammalian TEF factors []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Wuarin J |
Year: |
1992 |
Journal: |
J Cell Sci Suppl |
Title: |
The role of the transcriptional activator protein DBP in circadian liver gene expression. |
Volume: |
16 |
|
Pages: |
123-7 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
D site-binding protein (DBP) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. DBP may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It accumulates in the liver according to a very strong circadian rhythm regulated by hormones []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
287
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
281
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
201
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
230
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
70
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
106
 |
Fragment?: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
326
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
270
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirose K |
Year: |
2010 |
Journal: |
Blood |
Title: |
Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19). |
Volume: |
116 |
Issue: |
6 |
Pages: |
962-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Waters KM |
Year: |
2013 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Hepatic leukemia factor promotes resistance to cell death: implications for therapeutics and chronotherapy. |
Volume: |
268 |
Issue: |
2 |
Pages: |
141-8 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Hepatic leukemia factor (HLF) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. HLF binds DNA specifically as a homodimer or as a heterodimer with other PAR factors. It binds to the consensus sequence 5'-GTTACGTAAT-3' []. In B-precursor acute lymphoblastic leukemia (ALL), it fuses to the N terminus of the E2A protein [], and this chimeric protein promotes cell survival of t(17;19)-ALL cells by aberrantly up-regulating the expression of hematopoiesis transcription regulator LMO2 []. HLF regulates a complex multi-gene transcriptional program that involves upregulation of anti-apoptotic genes and downregulation of pro-apoptotic genes []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Belandia B |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors. |
Volume: |
275 |
Issue: |
40 |
Pages: |
30801-5 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
301
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
285
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Maeda T |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation. |
Volume: |
277 |
Issue: |
50 |
Pages: |
48889-98 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
307
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
202
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
150
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
307
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
307
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
307
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Pobbati AV |
Year: |
2012 |
Journal: |
Structure |
Title: |
Structural and functional similarity between the Vgll1-TEAD and the YAP-TEAD complexes. |
Volume: |
20 |
Issue: |
7 |
Pages: |
1135-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Farrance IK |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
The role of transcription enhancer factor-1 (TEF-1) related proteins in the formation of M-CAT binding complexes in muscle and non-muscle tissues. |
Volume: |
271 |
Issue: |
14 |
Pages: |
8266-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Appukuttan B |
Year: |
2007 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Identification of novel alternatively spliced isoforms of RTEF-1 within human ocular vascular endothelial cells and murine retina. |
Volume: |
48 |
Issue: |
8 |
Pages: |
3775-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shie JL |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells. |
Volume: |
279 |
Issue: |
24 |
Pages: |
25010-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The TEAD family (also known as TEF family) transcription factors play a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. TEAD transcription factors act by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction [, ].Four TEAD genes exist in mammals (TEAD 1 to 4). TEAD3 (transcriptional enhancer factor TEF-5) has a role in placental development []. |
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Protein Domain |
Type: |
Family |
Description: |
The TEAD family (also known as the TEF family) transcription factors play a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. TEAD transcription factors act by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction [, ].Four TEAD genes exist in mammals (TEAD 1 to 4). TEAD4 protein (also known as TEF-3) was reported to regulate muscle-specific genes in cardiac and smooth muscle cells []. Alternatively spliced transcripts for TEAD4 have been identified in human retinal vascular endothelial cells []. TEAD4 protein has been shown to enhance VEGF gene expression in bovine aortic endothelial cells []. |
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Protein Domain |
Type: |
Family |
Description: |
The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA-binding domain. Transcriptional activation by these proteins likely requires interactions with specific coactivators.In Drosophila, Vestigial (Vg) has a short 25 aa motif necessary and sufficient to interact with Scalloped (Sd) to form a complex. This motif is also present in four mammalian proteins, which are named Vestigial-like proteins (Vgl1-4) [, , ].In Drosophila, the Vg-Sd complex binds DNA through the Sd TEA/ATTS domain. The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wing outgrowth when ectopically expressed. This short conserved region is needed for interaction with Sd [].Mammalian Vgl-1 may promote cancer progression []. Vgl-2 interacts with TEF-1and MEF2 to promote skeletal muscle differentiation []. Vgl-4, is the only member of the Vestigial-like family expressed in the heart []. |
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Publication |
First Author: |
Jacquemin P |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain. |
Volume: |
271 |
Issue: |
36 |
Pages: |
21775-85 |
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Publication |
First Author: |
Jacquemin P |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. |
Volume: |
272 |
Issue: |
20 |
Pages: |
12928-37 |
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Publication |
First Author: |
Que J |
Year: |
2007 |
Journal: |
Development |
Title: |
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. |
Volume: |
134 |
Issue: |
13 |
Pages: |
2521-31 |
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Publication |
First Author: |
Böhm F |
Year: |
2010 |
Journal: |
Gastroenterology |
Title: |
FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice. |
Volume: |
139 |
Issue: |
4 |
Pages: |
1385-96 |
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Publication |
First Author: |
Masumoto KH |
Year: |
2010 |
Journal: |
Curr Biol |
Title: |
Acute induction of Eya3 by late-night light stimulation triggers TSHβ expression in photoperiodism. |
Volume: |
20 |
Issue: |
24 |
Pages: |
2199-206 |
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Publication |
First Author: |
Günther S |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. |
Volume: |
32 |
Issue: |
2 |
Pages: |
791-802 |
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Publication |
First Author: |
Que J |
Year: |
2006 |
Journal: |
Differentiation |
Title: |
Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. |
Volume: |
74 |
Issue: |
7 |
Pages: |
422-37 |
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Publication |
First Author: |
Jin Y |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
RTEF-1, an upstream gene of hypoxia-inducible factor-1α, accelerates recovery from ischemia. |
Volume: |
286 |
Issue: |
25 |
Pages: |
22699-705 |
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Publication |
First Author: |
Zhao B |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
TEAD mediates YAP-dependent gene induction and growth control. |
Volume: |
22 |
Issue: |
14 |
Pages: |
1962-71 |
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Publication |
First Author: |
Zhang H |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. |
Volume: |
284 |
Issue: |
20 |
Pages: |
13355-62 |
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Publication |
First Author: |
Hitzler JK |
Year: |
1999 |
Journal: |
Brain Res |
Title: |
Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice. |
Volume: |
820 |
Issue: |
1-2 |
Pages: |
1-11 |
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Publication |
First Author: |
Lee S |
Year: |
2009 |
Journal: |
Int J Oncol |
Title: |
Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches. |
Volume: |
34 |
Issue: |
1 |
Pages: |
161-72 |
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Publication |
First Author: |
Hajduk P |
Year: |
2010 |
Journal: |
Pediatr Surg Int |
Title: |
Mesenchymal expression of Tbx4 gene is not altered in Adriamycin mouse model. |
Volume: |
26 |
Issue: |
4 |
Pages: |
407-11 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
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Fragment?: |
true |
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