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Search results 101 to 200 out of 427 for Tiam1

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Type Details Score
GXD Expression    
Probe: MGI:2662995
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759722
Stage: TS22
Assay Id: MGI:2666223
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:2666222
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:2662995
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:2666223
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1776322
Stage: TS22
Assay Id: MGI:2666222
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:2662995
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666223
Age: embryonic day 10.5
Image: Tiam1 10.5dpc
Specimen Label: Tiam1 10.5dpc
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666917
Stage: TS17
Assay Id: MGI:2666222
Age: embryonic day 10.5
Image: Tiam1 10.5dpc
Specimen Label: Tiam1 10.5dpc
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:2666222
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:2662995
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:2666223
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1591  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1591  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: false
Publication
First Author: Shepherd TR
Year: 2010
Journal: J Mol Biol
Title: The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
Volume: 398
Issue: 5
Pages: 730-46
Publication  
First Author: Strumane K
Year: 2006
Journal: Methods Enzymol
Title: The Rac activator Tiam1 and Ras-induced oncogenesis.
Volume: 407
Pages: 269-81
Publication
First Author: Lambert JM
Year: 2002
Journal: Nat Cell Biol
Title: Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism.
Volume: 4
Issue: 8
Pages: 621-5
Publication
First Author: Tanaka M
Year: 2004
Journal: EMBO J
Title: Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2.
Volume: 23
Issue: 5
Pages: 1075-88
Publication
First Author: Gérard A
Year: 2009
Journal: Blood
Title: The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
Volume: 113
Issue: 24
Pages: 6138-47
Publication
First Author: Li L
Year: 2023
Journal: Neuron
Title: Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain.
Volume: 111
Issue: 13
Pages: 2038-2050.e6
Publication
First Author: Malliri A
Year: 2002
Journal: Nature
Title: Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Volume: 417
Issue: 6891
Pages: 867-71
Publication
First Author: Habets GG
Year: 1995
Journal: Cytogenet Cell Genet
Title: The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16.
Volume: 70
Issue: 1-2
Pages: 48-51
Publication
First Author: Kou W
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice.
Volume: 497
Issue: 1
Pages: 248-255
GXD Expression      
Probe: MGI:331650
Assay Type: RNA in situ
Annotation Date: 2003-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:2674586
Age: embryonic day 9.5
Specimen Label: Tiam1 9.5dpc
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2674663
Age: embryonic day 9.5
Note: The expression was widespread.
Specimen Label: Tiam1 9.5dpc
Detected: true
Specimen Num: 1
Publication
First Author: Yue Y
Year: 2021
Journal: FASEB J
Title: Tiam1 mediates Rac1 activation and contraction-induced glucose uptake in skeletal muscle cells.
Volume: 35
Issue: 2
Pages: e21210
Publication
First Author: Hamelers IH
Year: 2005
Journal: J Cell Biol
Title: The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.
Volume: 171
Issue: 5
Pages: 871-81
Publication
First Author: Rygiel TP
Year: 2008
Journal: J Cell Sci
Title: The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.
Volume: 121
Issue: Pt 8
Pages: 1183-92
Publication
First Author: Wang S
Year: 2012
Journal: J Cell Biol
Title: Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
Volume: 199
Issue: 2
Pages: 331-45
Publication
First Author: Malliri A
Year: 2006
Journal: J Biol Chem
Title: The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
Volume: 281
Issue: 1
Pages: 543-8
Publication
First Author: Mack NA
Year: 2012
Journal: Nat Cell Biol
Title: β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity.
Volume: 14
Issue: 11
Pages: 1169-80
Publication
First Author: Boissier P
Year: 2014
Journal: Cell Signal
Title: The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
Volume: 26
Issue: 3
Pages: 483-91
Publication
First Author: Čajánek L
Year: 2013
Journal: Mol Cell Biol
Title: Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
Volume: 33
Issue: 1
Pages: 59-70
Publication
First Author: Cheng J
Year: 2021
Journal: J Neurosci
Title: The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions.
Volume: 41
Issue: 6
Pages: 1191-1206
Protein
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
Publication
First Author: Mertens AE
Year: 2005
Journal: J Cell Biol
Title: The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex.
Volume: 170
Issue: 7
Pages: 1029-37
Protein
Organism: Mus musculus/domesticus
Length: 1496  
Fragment?: false
Publication
First Author: Ellenbroek SI
Year: 2012
Journal: Small GTPases
Title: The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network.
Volume: 3
Issue: 1
Pages: 4-14
Protein
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: false
Publication
First Author: Diamantopoulou Z
Year: 2017
Journal: Cancer Cell
Title: TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
Volume: 31
Issue: 5
Pages: 621-634.e6
Publication
First Author: Habets GG
Year: 1994
Journal: Cell
Title: Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.
Volume: 77
Issue: 4
Pages: 537-49
Protein
Organism: Mus musculus/domesticus
Length: 743  
Fragment?: true
Publication
First Author: Terawaki S
Year: 2010
Journal: EMBO J
Title: The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.
Volume: 29
Issue: 1
Pages: 236-50
GXD Expression      
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191477
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tiam1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191477
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tiam1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tiam1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191477
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tiam1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191477
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tiam1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tiam1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tiam1
Detected: true
Specimen Num: 6
Publication
First Author: Miyamoto Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology.
Volume: 103
Issue: 27
Pages: 10444-9
Publication
First Author: Liu C
Year: 2011
Journal: Hum Genet
Title: Genetic analysis of Down syndrome-associated heart defects in mice.
Volume: 130
Issue: 5
Pages: 623-32
Publication
First Author: Strumane K
Year: 2008
Journal: Leuk Res
Title: Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency.
Volume: 32
Issue: 1
Pages: 113-20
Publication
First Author: Strumane K
Year: 2009
Journal: J Cancer Res Clin Oncol
Title: Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Volume: 135
Issue: 1
Pages: 69-80
Publication
First Author: Ma HL
Year: 2015
Journal: Biol Reprod
Title: Inhibition of Endometrial Tiam1/Rac1 Signals Induced by miR-22 Up-Regulation Leads to the Failure of Embryo Implantation During the Implantation Window in Pregnant Mice.
Volume: 92
Issue: 6
Pages: 152
Publication
First Author: Matsuo N
Year: 2002
Journal: J Biol Chem
Title: Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.
Volume: 277
Issue: 4
Pages: 2860-8
Publication
First Author: Um K
Year: 2014
Journal: Dev Cell
Title: Dynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex.
Volume: 29
Issue: 6
Pages: 701-15
Publication
First Author: Michiels F
Year: 1997
Journal: J Cell Biol
Title: Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
Volume: 137
Issue: 2
Pages: 387-98
Publication  
First Author: Kojima H
Year: 2019
Journal: Neurobiol Learn Mem
Title: The role of CaMKII-Tiam1 complex on learning and memory.
Volume: 166
Pages: 107070
Publication  
First Author: Kurdi AT
Year: 2016
Journal: Nat Commun
Title: Tiam1/Rac1 complex controls Il17a transcription and autoimmunity.
Volume: 7
Pages: 13048
Publication
First Author: Filippi BM
Year: 2008
Journal: Biochim Biophys Acta
Title: SRC-dependent signalling regulates actin ruffle formation induced by glycerophosphoinositol 4-phosphate.
Volume: 1783
Issue: 12
Pages: 2311-22
Publication
First Author: Pegtel DM
Year: 2007
Journal: Curr Biol
Title: The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity.
Volume: 17
Issue: 19
Pages: 1623-34
Publication
First Author: Sasaki N
Year: 2010
Journal: Mol Cell Neurosci
Title: Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation.
Volume: 45
Issue: 4
Pages: 335-44
Publication
First Author: Wu Y
Year: 2024
Journal: J Cell Mol Med
Title: Decreased Tiam1-mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia.
Volume: 28
Issue: 11
Pages: e18443
Publication
First Author: Benoist M
Year: 2013
Journal: EMBO J
Title: MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression.
Volume: 32
Issue: 16
Pages: 2287-99
Publication  
First Author: Machin PA
Year: 2023
Journal: Front Immunol
Title: Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Volume: 14
Pages: 1180886
Publication  
First Author: Thelen F
Year: 2021
Journal: Front Immunol
Title: The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis.
Volume: 12
Pages: 716405
Publication
First Author: Landin Malt A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Par3 is essential for the establishment of planar cell polarity of inner ear hair cells.
Volume: 116
Issue: 11
Pages: 4999-5008
Publication
First Author: Tian Y
Year: 2011
Journal: Development
Title: Regulation of lung endoderm progenitor cell behavior by miR302/367.
Volume: 138
Issue: 7
Pages: 1235-45
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Yoo S
Year: 2012
Journal: Mol Cells
Title: A gene trap knockout of the Tiam-1 protein results in malformation of the early embryonic brain.
Volume: 34
Issue: 1
Pages: 103-8
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Stomach
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Muscle
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Skin
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2665891
Assay Type: RT-PCR
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:2666051
Age: postnatal adult
Specimen Label: Eyes
Detected: true
Specimen Num: 12