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Search results 101 to 170 out of 170 for Tlr8

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Type Details Score
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
24277153 | J:266818
First Author: Guiducci C
Year: 2013
Journal: J Exp Med
Title: RNA recognition by human TLR8 can lead to autoimmune inflammation.
Volume: 210
Issue: 13
Pages: 2903-19
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Publication
38589923 | J:361377
First Author: Wang T
Year: 2024
Journal: Cell Commun Signal
Title: MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.
Volume: 22
Issue: 1
Pages: 220
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Publication
18490763 | J:136380
First Author: Butchi NB
Year: 2008
Journal: J Immunol
Title: Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.
Volume: 180
Issue: 11
Pages: 7604-12
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Publication
21734241 | J:177096
First Author: Prinz N
Year: 2011
Journal: Blood
Title: Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells.
Volume: 118
Issue: 8
Pages: 2322-32
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GO Term
GO:0034158 | toll-like receptor 8 signaling pathway
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Allele
Tlr7<tm3(TLR7)Smoc> | MGI:7292817
Name: toll-like receptor 7; targeted mutation 3, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tlr8<tm3(TLR8)Smoc> | MGI:7292818
Name: toll-like receptor 8; targeted mutation 3, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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GO Term
GO:0034161 | positive regulation of toll-like receptor 8 signaling pathway
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GO Term
GO:0034159 | regulation of toll-like receptor 8 signaling pathway
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GO Term
GO:0034160 | negative regulation of toll-like receptor 8 signaling pathway
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Publication
15804288 | -
First Author: Philbin VJ
Year: 2005
Journal: Immunology
Title: Identification and characterization of a functional, alternatively spliced Toll-like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens.
Volume: 114
Issue: 4
Pages: 507-21
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Strain
MGI:6429671 | C57BL/6JSmoc-Tlr7<tm3(TLR7)Smoc> Tlr8<tm3(TLR8)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
Q9D3J9
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein
Q8BHV4
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
A2ALN9
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Protein
Q08EG0
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Publication
31001245 | -
 
First Author: Harris VM
Year: 2019
Journal: Front Immunol
Title: Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21.
Volume: 10
Pages: 578
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Publication
32433612 | -
First Author: Heinz LX
Year: 2020
Journal: Nature
Title: TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Volume: 581
Issue: 7808
Pages: 316-322
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Publication
18836453 | -
First Author: Chen W
Year: 2008
Journal: Nat Struct Mol Biol
Title: Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Volume: 15
Issue: 11
Pages: 1213-20
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Publication
11303025 | -
First Author: Barnes BJ
Year: 2001
Journal: J Biol Chem
Title: Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.
Volume: 276
Issue: 26
Pages: 23382-90
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Publication
17881657 | -
First Author: Dideberg V
Year: 2007
Journal: Hum Mol Genet
Title: An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases.
Volume: 16
Issue: 24
Pages: 3008-16
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Publication
15657875 | -
First Author: Sigurdsson S
Year: 2005
Journal: Am J Hum Genet
Title: Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
Volume: 76
Issue: 3
Pages: 528-37
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Publication
15695821 | -
First Author: Schoenemeyer A
Year: 2005
Journal: J Biol Chem
Title: The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Volume: 280
Issue: 17
Pages: 17005-12
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Protein Domain
IPR029838 | IRF5
Type: Family
Description: Interferon regulatory factor 5 (IRF5) is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection []. It is activated by TLR7 or TLR8 signalling []. Its structure has been revealed []. Variations of the IRF5 gene affects the susceptibility of a few diseases, such as inflammatory bowel disease 14 (IBD14) [], systemic lupus erythematosus 10 (SLEB10) []and Rheumatoid arthritis (RA).
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Protein Domain
IPR027869 | TASL
Type: Family
Description: In humans, TASL (TLR adaptor interacting with SLC15A4 on the lysosome) is encoded by CXorf21 that is associated with systemic lupus erythematosus []. It is an immune adaptor that is required for recruitment and activation of IRF5 by TLR7, TLR8 and TLR9, in mechanistic analogy to IRF3 and its three adaptors STING, MAVS and TRIF. TASL interacts with the endolysosomal transporter SLC15A4; the SLC15A4-TASL complex is required for endolysosomal TLR signalling. TASL contains a pLxIS motif that is important for its function [].
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Publication
15361868 | J:336429
First Author: Kawai T
Year: 2004
Journal: Nat Immunol
Title: Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.
Volume: 5
Issue: 10
Pages: 1061-8
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Publication
36474072 | J:332569
First Author: Allen RM
Year: 2022
Journal: Nat Cell Biol
Title: LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8.
Volume: 24
Issue: 12
Pages: 1701-1713
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Publication
29625894 | J:305317
First Author: Ohto U
Year: 2018
Journal: Immunity
Title: Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation.
Volume: 48
Issue: 4
Pages: 649-658.e4
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Publication
28530246 | J:337022
 
First Author: Pohar J
Year: 2017
Journal: Nat Commun
Title: Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9.
Volume: 8
Pages: 15363
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Publication
37075115 | J:335304
First Author: Bhagchandani SH
Year: 2023
Journal: Sci Adv
Title: Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation.
Volume: 9
Issue: 16
Pages: eadg2239
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Publication
18544685 | J:138732
First Author: Wang JP
Year: 2008
Journal: Blood
Title: Toll-like receptor-mediated activation of neutrophils by influenza A virus.
Volume: 112
Issue: 5
Pages: 2028-34
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Publication
29452403 | J:259396
First Author: Miyake K
Year: 2018
Journal: Int Immunol
Title: Mechanisms controlling nucleic acid-sensing Toll-like receptors.
Volume: 30
Issue: 2
Pages: 43-51
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Publication
33188181 | J:300841
First Author: Cho SX
Year: 2020
Journal: Nat Commun
Title: Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.
Volume: 11
Issue: 1
Pages: 5794
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Publication
34525198 | J:322749
First Author: Kovtonyuk LV
Year: 2022
Journal: Blood
Title: IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice.
Volume: 139
Issue: 1
Pages: 44-58
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Publication
31086057 | J:289691
 
First Author: Conte C
Year: 2019
Journal: Int J Mol Sci
Title: Niemann-Pick Type A Disease: Behavior of Neutral Sphingomyelinase and Vitamin D Receptor.
Volume: 20
Issue: 9
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Publication
29321259 | J:257264
 
First Author: Ah Kioon MD
Year: 2018
Journal: Sci Transl Med
Title: Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8.
Volume: 10
Issue: 423
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Publication
26489884 | J:250240
First Author: Shibata T
Year: 2016
Journal: Int Immunol
Title: Guanosine and its modified derivatives are endogenous ligands for TLR7.
Volume: 28
Issue: 5
Pages: 211-22
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Publication
21850221 | J:176517
First Author: Jeudy S
Year: 2011
Journal: PLoS One
Title: Bcl-2 inhibits the innate immune response during early pathogenesis of murine congenital muscular dystrophy.
Volume: 6
Issue: 8
Pages: e22369
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Publication
37871107 | J:342213
First Author: Ha JY
Year: 2023
Journal: PLoS Pathog
Title: Periodontitis promotes bacterial extracellular vesicle-induced neuroinflammation in the brain and trigeminal ganglion.
Volume: 19
Issue: 10
Pages: e1011743
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Publication
21483755 | J:171659
First Author: Menendez D
Year: 2011
Journal: PLoS Genet
Title: The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.
Volume: 7
Issue: 3
Pages: e1001360
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Publication
21628060 | J:176753
First Author: Zhu W
Year: 2011
Journal: Cell Immunol
Title: Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells.
Volume: 270
Issue: 2
Pages: 156-63
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Publication
27003259 | J:234870
First Author: Nyberg WA
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Imiquimod induces ER stress and Ca(2+) influx independently of TLR7 and TLR8.
Volume: 473
Issue: 4
Pages: 789-794
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HT Experiment
E-GEOD-9287 | Differential gene expression in wild-type versus Yaa mutant mouse spleen cells
Series Id: GSE9287
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
29574762 | J:267397
First Author: Choudry M
Year: 2018
Journal: Immunology
Title: Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice.
Volume: 155
Issue: 1
Pages: 85-98
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Protein
E9Q5T2
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
A0A0N4SVY5
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: true
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Protein
P56477
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
Q3U169
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
F6Z6C6
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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Protein
B2CC69
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
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