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Search results 101 to 117 out of 117 for Tmod4

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Type

Details

Score

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

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Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

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Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

1370827 | -

First Author:	Sung LA
Year:	1992
Journal:	J Biol Chem
Title:	Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein.
Volume:	267
Issue:	4
Pages:	2616-21

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Publication

24500875 | J:211921

First Author:	McKeown CR
Year:	2014
Journal:	Dev Dyn
Title:	Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo.
Volume:	243
Issue:	6
Pages:	800-17

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Publication

24922351 | -

First Author:	Lewis RA
Year:	2014
Journal:	Cytoskeleton (Hoboken)
Title:	Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3.
Volume:	71
Issue:	7
Pages:	395-411

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Publication

12975349 | -

First Author:	Mudry RE
Year:	2003
Journal:	J Cell Biol
Title:	The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes.
Volume:	162
Issue:	6
Pages:	1057-68

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Protein Domain

IPR030135 | TMOD1

Type:

Family

Description:

The Tropomodulin (Tmod) family consist of four Tmods (Tmods 1-4) and three larger variants termed leiomodins (Lmods 1-3), which are expressed in a tissue-specific and developmentally regulated fashion []. Members of the Tmod family are actin filament pointed-end-capping proteins that regulate actin subunit association and dissociation from pointed ends in a tropomyosin-dependent manner [].Tropomodulin1 (Tmod1) was originally known to as E-Tmod, as it was first identified as a binding partner of tropomyosin (TM) in red blood cells (RBC) []. Tmod1 is predominantly expressed in terminally differentiated, post-mitotic cells (such as RBCs, lens fibre cells, neurons, andstriated muscle). Tmod1 binds with F-actin []. It is essential for stabilising F-actin at cell-cell junctions, which may be required for maintenance of cell shapes during embryonic cardiac morphogenesis []. It also regulates actin dynamics to control the precise lengths of the long alpha/beta tropomyosin-coated actin filaments in mature cardiac myofibrils [, ]. Tmod1 and Tmod4 maintain thin filament stability and correctly specified thin filament lengths in cardiac muscles via their interactions with terminal tropomyosins and their ability to regulate actin subunit exchange at pointed ends []. Tmod1's structure has been solved [].

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Protein

G3UYG4

Organism:	Mus musculus/domesticus
Length:	47
Fragment?:	true

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Publication

25061212 | -

First Author:	Rao JN
Year:	2014
Journal:	Science
Title:	Mechanism of actin filament pointed-end capping by tropomodulin.
Volume:	345
Issue:	6195
Pages:	463-7

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Protein

P49813

Organism:	Mus musculus/domesticus
Length:	359
Fragment?:	false

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