Type |
Details |
Score |
Publication |
First Author: |
Karamita M |
Year: |
2017 |
Journal: |
JCI Insight |
Title: |
Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia. |
Volume: |
2 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mohammed FF |
Year: |
2004 |
Journal: |
Nat Genet |
Title: |
Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. |
Volume: |
36 |
Issue: |
9 |
Pages: |
969-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quin C |
Year: |
2024 |
Journal: |
Blood Adv |
Title: |
Chronic TNF in the aging microenvironment exacerbates Tet2 loss-of-function myeloid expansion. |
Volume: |
8 |
Issue: |
15 |
Pages: |
4169-4180 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heaton WL |
Year: |
2018 |
Journal: |
Leukemia |
Title: |
Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Liu J |
Year: |
1998 |
Journal: |
Nat Med |
Title: |
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. |
Volume: |
4 |
Issue: |
1 |
Pages: |
78-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Togbe D |
Year: |
2007 |
Journal: |
Eur J Immunol |
Title: |
T cell-derived TNF down-regulates acute airway response to endotoxin. |
Volume: |
37 |
Issue: |
3 |
Pages: |
768-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bradford EM |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. |
Volume: |
199 |
Issue: |
5 |
Pages: |
1886-1897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iqbal J |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
TNF regulates cellular NAD+ metabolism in primary macrophages. |
Volume: |
342 |
Issue: |
4 |
Pages: |
1312-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bopst M |
Year: |
2001 |
Journal: |
Eur J Immunol |
Title: |
Differential effects of TNF and LTalpha in the host defense against M. bovis BCG. |
Volume: |
31 |
Issue: |
6 |
Pages: |
1935-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alexopoulou L |
Year: |
2006 |
Journal: |
Eur J Immunol |
Title: |
Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity. |
Volume: |
36 |
Issue: |
10 |
Pages: |
2768-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kassiotis G |
Year: |
1999 |
Journal: |
Eur J Immunol |
Title: |
TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis. |
Volume: |
29 |
Issue: |
3 |
Pages: |
774-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vila-del Sol V |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Involvement of TNF and NF-kappa B in the transcriptional control of cyclooxygenase-2 expression by IFN-gamma in macrophages. |
Volume: |
174 |
Issue: |
5 |
Pages: |
2825-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kozik AJ |
Year: |
2017 |
Journal: |
Exp Mol Pathol |
Title: |
Age, sex, and TNF associated differences in the gut microbiota of mice and their impact on acute TNBS colitis. |
Volume: |
103 |
Issue: |
3 |
Pages: |
311-319 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuprash DV |
Year: |
2008 |
Journal: |
Cancer Lett |
Title: |
Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice. |
Volume: |
268 |
Issue: |
1 |
Pages: |
70-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peschon JJ |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. |
Volume: |
160 |
Issue: |
2 |
Pages: |
943-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morgan JA |
Year: |
2018 |
Journal: |
Behav Brain Res |
Title: |
TNF signalling via the TNF receptors mediates the effects of exercise on cognition-like behaviours. |
Volume: |
353 |
|
Pages: |
74-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kemp GM |
Year: |
2022 |
Journal: |
Mol Psychiatry |
Title: |
Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress. |
Volume: |
27 |
Issue: |
11 |
Pages: |
4474-4484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Secher T |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. |
Volume: |
182 |
Issue: |
12 |
Pages: |
7855-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Régnier CH |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice. |
Volume: |
99 |
Issue: |
8 |
Pages: |
5585-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cherfils-Vicini J |
Year: |
2008 |
Journal: |
Immunology |
Title: |
Characterization of immune functions in TRAF4-deficient mice. |
Volume: |
124 |
Issue: |
4 |
Pages: |
562-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang YH |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Annexin-1 regulates macrophage IL-6 and TNF via glucocorticoid-induced leucine zipper. |
Volume: |
183 |
Issue: |
2 |
Pages: |
1435-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuzin II |
Year: |
2015 |
Journal: |
Cell Immunol |
Title: |
TNF signals are dispensable for the generation of CD23+ CD21/35-high CD1d-high B cells in inflamed lymph nodes. |
Volume: |
296 |
Issue: |
2 |
Pages: |
133-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Tumor necrosis factor-α and lymphotoxin-α mediate myocardial ischemic injury via TNF receptor 1, but are cardioprotective when activating TNF receptor 2. |
Volume: |
8 |
Issue: |
5 |
Pages: |
e60227 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ortiz LA |
Year: |
1998 |
Journal: |
Exp Lung Res |
Title: |
Expression of TNF and the necessity of TNF receptors in bleomycin-induced lung injury in mice. |
Volume: |
24 |
Issue: |
6 |
Pages: |
721-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamano R |
Year: |
2011 |
Journal: |
Eur J Immunol |
Title: |
TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40. |
Volume: |
41 |
Issue: |
7 |
Pages: |
2010-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kroner A |
Year: |
2014 |
Journal: |
Neuron |
Title: |
TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. |
Volume: |
83 |
Issue: |
5 |
Pages: |
1098-116 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruuls SR |
Year: |
2001 |
Journal: |
Immunity |
Title: |
Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation. |
Volume: |
15 |
Issue: |
4 |
Pages: |
533-43 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Oganesyan G |
Year: |
2006 |
Journal: |
Nature |
Title: |
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. |
Volume: |
439 |
Issue: |
7073 |
Pages: |
208-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith RM |
Year: |
2001 |
Journal: |
Mol Cell Biochem |
Title: |
TNF alpha is required for hypoxia-mediated right ventricular hypertrophy. |
Volume: |
219 |
Issue: |
1-2 |
Pages: |
139-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Myles IA |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome. |
Volume: |
128 |
Issue: |
8 |
Pages: |
3595-3604 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baseta JG |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. |
Volume: |
165 |
Issue: |
10 |
Pages: |
5621-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Complementary effects of TNF and lymphotoxin on the formation of germinal center and follicular dendritic cells. |
Volume: |
166 |
Issue: |
1 |
Pages: |
330-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leclerc M |
Year: |
2016 |
Journal: |
Blood |
Title: |
Control of GVHD by regulatory T cells depends on TNF produced by T cells and TNFR2 expressed by regulatory T cells. |
Volume: |
128 |
Issue: |
12 |
Pages: |
1651-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao XJ |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol. |
Volume: |
181 |
Issue: |
5 |
Pages: |
3049-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kendall GS |
Year: |
2011 |
Journal: |
Lab Invest |
Title: |
TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult. |
Volume: |
91 |
Issue: |
3 |
Pages: |
328-41 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chatzidakis I |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells. |
Volume: |
178 |
Issue: |
11 |
Pages: |
6735-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huber SA |
Year: |
2005 |
Journal: |
J Virol |
Title: |
Roles of tumor necrosis factor alpha (TNF-alpha) and the p55 TNF receptor in CD1d induction and coxsackievirus B3-induced myocarditis. |
Volume: |
79 |
Issue: |
5 |
Pages: |
2659-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lacey D |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis. |
Volume: |
112 |
Issue: |
31 |
Pages: |
9698-703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wree A |
Year: |
2018 |
Journal: |
Hepatology |
Title: |
NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice. |
Volume: |
67 |
Issue: |
2 |
Pages: |
736-749 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. |
Volume: |
179 |
Issue: |
1 |
Pages: |
154-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olleros ML |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Transmembrane TNF induces an efficient cell-mediated immunity and resistance to Mycobacterium bovis bacillus Calmette-Guérin infection in the absence of secreted TNF and lymphotoxin-alpha. |
Volume: |
168 |
Issue: |
7 |
Pages: |
3394-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beutler B |
Year: |
1994 |
Journal: |
Science |
Title: |
Unraveling function in the TNF ligand and receptor families. |
Volume: |
264 |
Issue: |
5159 |
Pages: |
667-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng J |
Year: |
1992 |
Journal: |
Genes Dev |
Title: |
Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice. |
Volume: |
6 |
Issue: |
8 |
Pages: |
1444-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Webb LV |
Year: |
2016 |
Journal: |
J Exp Med |
Title: |
TNF activation of NF-κB is essential for development of single-positive thymocytes. |
Volume: |
213 |
Issue: |
8 |
Pages: |
1399-407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akassoglou K |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. |
Volume: |
158 |
Issue: |
1 |
Pages: |
438-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanazawa K |
Year: |
2003 |
Journal: |
J Bone Miner Res |
Title: |
TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis. |
Volume: |
18 |
Issue: |
3 |
Pages: |
443-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kassiotis G |
Year: |
2001 |
Journal: |
J Exp Med |
Title: |
Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination. |
Volume: |
193 |
Issue: |
4 |
Pages: |
427-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGeough MD |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies. |
Volume: |
127 |
Issue: |
12 |
Pages: |
4488-4497 |
|
•
•
•
•
•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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|
Gene |
Type: |
gene |
Organism: |
human |
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•
•
•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
•
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Gene |
Type: |
gene |
Organism: |
human |
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•
•
•
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Gene |
Type: |
gene |
Organism: |
human |
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•
•
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
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Organism: |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
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Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
•
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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•
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Publication |
First Author: |
Armaka M |
Year: |
2008 |
Journal: |
J Exp Med |
Title: |
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. |
Volume: |
205 |
Issue: |
2 |
Pages: |
331-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schick J |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
Cutting Edge: TNF Is Essential for Mycobacteria-Induced MINCLE Expression, Macrophage Activation, and Th17 Adjuvanticity. |
Volume: |
205 |
Issue: |
2 |
Pages: |
323-328 |
|
•
•
•
•
•
|
Publication |
First Author: |
Furuta T |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Protective roles of mast cells and mast cell-derived TNF in murine malaria. |
Volume: |
177 |
Issue: |
5 |
Pages: |
3294-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grivennikov SI |
Year: |
2005 |
Journal: |
Immunity |
Title: |
Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects. |
Volume: |
22 |
Issue: |
1 |
Pages: |
93-104 |
|
•
•
•
•
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Publication |
First Author: |
Lee CS |
Year: |
2023 |
Journal: |
Cell Death Differ |
Title: |
IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1575-1584 |
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Publication |
First Author: |
Ninnemann J |
Year: |
2022 |
Journal: |
Mucosal Immunol |
Title: |
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability. |
Volume: |
15 |
Issue: |
4 |
Pages: |
698-716 |
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