|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 139 out of 139 for Tob1

<< First    < Previous  |  Next >    Last >>
0.022s

Categories

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Kawamura-Tsuzuku J
Year: 2004
Journal: Oncogene
Title: Nuclear localization of Tob is important for regulation of its antiproliferative activity.
Volume: 23
Issue: 39
Pages: 6630-8
HT Experiment
Series Id: GSE21836
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Allele
Name: transducer of ErbB-2.1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Interaction Experiment
Description: Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
GXD Expression  
Probe: MGI:7662583
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716319
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7662603
Age: embryonic day 11.5
Note: Expression was often observed in association with Tob1 throughout the vesicle, and in larger cytoplasmic complexes in posterior vesicle cells.
Specimen Label: 2b
Detected: true
Specimen Num: 1
Publication
First Author: Xiong B
Year: 2006
Journal: Dev Cell
Title: Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.
Volume: 11
Issue: 2
Pages: 225-38
Protein Domain
Type: Family
Description: Tob (transducer of ErbB2) is a member of the BTG/Tob family. Tob2 consists of 344 amino acids with high similarity to the Tob1 protein. Like the Tob1 protein, Tob2 can inhibit cell cycle progression from the G0/G1 to S phases. This cell cycle regulatory function may occur in part, through their interaction with CAF1 [].The BTG/Tob family members contain an conserved N-terminal domain, known as APRO domain (AntiPROliferative) or BTG domain. In mammals, six family members have been identified: BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. They interact with CAF1, a subunit of the CCR4-NOT complex. They display antiproliferative properties as their ectopic expression in a variety of cell lines reduced cell proliferation [].
Protein Domain
Type: Family
Description: Tob1 and Tob2 are members of the BTG/Tob family.The BTG/Tob family members contain an conserved N-terminal domain, known as APRO domain (AntiPROliferative) or BTG domain. In mammals, six family members have been identified: BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. They interact with CAF1, a subunit of the CCR4-NOT complex. They display antiproliferative properties as their ectopic expression in a variety of cell lines reduced cell proliferation [].
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
Publication
First Author: Ng R
Year: 2017
Journal: Cell Rep
Title: miRNA-32 Drives Brown Fat Thermogenesis and Trans-activates Subcutaneous White Fat Browning in Mice.
Volume: 19
Issue: 6
Pages: 1229-1246
Publication
First Author: Ezzeddine N
Year: 2012
Journal: Mol Cell Biol
Title: Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.
Volume: 32
Issue: 6
Pages: 1089-98
Publication
First Author: Quan Y
Year: 2022
Journal: Nucleic Acids Res
Title: Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.
Volume: 50
Issue: 8
Pages: 4414-4435
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112