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Search results 101 to 200 out of 228 for Tomm20

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7467103
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7576641
Age: embryonic day 18.5
Image: 3E WT
Specimen Label: 3E WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7467103
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7576641
Age: embryonic day 18.5
Image: 3E KO
Note: Authors report prominent mitochondrial clustering.
Specimen Label: 3E KO
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: true
Specimen Num: 1
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:7619035
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7619072
Age: embryonic day 16.5
Note: Expression was in the outer membranes of mitochondria.
Specimen Label: 2D
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: false
Specimen Num: 1
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•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: false
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:969568
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525244
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: false
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: false
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:7467103
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7467170
Age: embryonic day 10.5
Note: Expression in mitochondria evenly distributed in cells.
Specimen Label: 4B Ctrl TOM20
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7467103
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7467170
Age: embryonic day 10.5
Note: Mitochondria clustered at one side of nuclei.
Specimen Label: 4B Mut TOM20
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6468562
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468577
Age: postnatal day 24-28
Image: 2E Control
Note: Expression is seen in the mitochondria of metaphase II (MII) oocytes.
Specimen Label: 2E Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6468562
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468577
Age: postnatal day 24-28
Image: 21E cKO
Note: Expression is seen in the mitochondria of metaphase II (MII) oocytes; no disorganization is observed in the mutant oocytes.
Specimen Label: 21E cKO
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6926
Specimen Label: GUDMAP:6926
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000695
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541255
Age: embryonic day 15.5
Image: GUDMAP:6925
Specimen Label: GUDMAP:6925
Detected: true
Specimen Num: 1
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Publication
34686324 | J:328736
First Author: Kosmach A
Year: 2021
Journal: Cell Rep
Title: Monitoring mitochondrial calcium and metabolism in the beating MCU-KO heart.
Volume: 37
Issue: 3
Pages: 109846
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Publication
12925707 | J:86030
First Author: Valentijn AJ
Year: 2003
Journal: J Cell Biol
Title: Spatial and temporal changes in Bax subcellular localization during anoikis.
Volume: 162
Issue: 4
Pages: 599-612
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Publication
24739386 | J:214107
First Author: Hikosaka K
Year: 2014
Journal: J Biol Chem
Title: Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes.
Volume: 289
Issue: 21
Pages: 14796-811
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Publication
23789093 | J:201079
First Author: Korrodi-Gregório L
Year: 2013
Journal: Biol Open
Title: TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network.
Volume: 2
Issue: 5
Pages: 453-65
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Publication
17185018 | J:121457
First Author: Ryazantsev S
Year: 2007
Journal: Mol Genet Metab
Title: Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis III B.
Volume: 90
Issue: 4
Pages: 393-401
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Publication
36857387 | J:334114
First Author: Ruthig VA
Year: 2023
Journal: PLoS Genet
Title: The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation.
Volume: 19
Issue: 3
Pages: e1010656
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Publication
24515348 | J:208253
First Author: Richter V
Year: 2014
Journal: J Cell Biol
Title: Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
Volume: 204
Issue: 4
Pages: 477-86
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Publication
25215947 | J:258689
First Author: Strappazzon F
Year: 2015
Journal: Cell Death Differ
Title: AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.
Volume: 22
Issue: 3
Pages: 419-32
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Publication
21454573 | J:172677
First Author: Kang BH
Year: 2011
Journal: J Biol Chem
Title: Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein.
Volume: 286
Issue: 19
Pages: 16758-67
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Publication
30158529 | J:266097
First Author: Shanmughapriya S
Year: 2018
Journal: Nat Commun
Title: FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation.
Volume: 9
Issue: 1
Pages: 3449
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Publication
24191052 | J:202975
First Author: Mashimo M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress.
Volume: 110
Issue: 47
Pages: 18964-9
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Publication
30951587 | J:277128
First Author: Shiromoto Y
Year: 2019
Journal: Biol Reprod
Title: GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.
Volume: 101
Issue: 1
Pages: 248-256
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Publication
25139855 | J:214812
First Author: Chaffee BR
Year: 2014
Journal: Development
Title: Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.
Volume: 141
Issue: 17
Pages: 3388-98
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Publication
39482367 | J:357841
First Author: Ohanele C
Year: 2024
Journal: Commun Biol
Title: The mitochondrial citrate carrier SLC25A1 regulates metabolic reprogramming and morphogenesis in the developing heart.
Volume: 7
Issue: 1
Pages: 1422
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Publication
36048019 | J:328139
First Author: Li J
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses.
Volume: 63
Issue: 10
Pages: 1
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Publication
21126574 | J:171179
First Author: d'Amora M
Year: 2011
Journal: J Chem Neuroanat
Title: Expression of PINK1 in the brain, eye and ear of mouse during embryonic development.
Volume: 41
Issue: 2
Pages: 73-85
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Publication
39043703 | J:352092
First Author: Wang L
Year: 2024
Journal: Nat Commun
Title: Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition.
Volume: 15
Issue: 1
Pages: 6209
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Publication
22357545 | J:185833
First Author: Fernandes R
Year: 2012
Journal: Biol Reprod
Title: NLRP5 mediates mitochondrial function in mouse oocytes and embryos.
Volume: 86
Issue: 5
Pages: 138, 1-10
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Publication
25327288 | J:217701
First Author: Dowdle WE
Year: 2014
Journal: Nat Cell Biol
Title: Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Volume: 16
Issue: 11
Pages: 1069-79
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Publication
20671748 | J:186336
First Author: Cleland MM
Year: 2011
Journal: Cell Death Differ
Title: Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
Volume: 18
Issue: 2
Pages: 235-47
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Publication
23479732 | J:198392
First Author: Morishita H
Year: 2013
Journal: J Biol Chem
Title: Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation.
Volume: 288
Issue: 16
Pages: 11436-47
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Publication
38658571 | J:347584
First Author: Xing L
Year: 2024
Journal: Nat Commun
Title: Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development.
Volume: 15
Issue: 1
Pages: 3468
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Publication
34048705 | J:307067
First Author: Jiao H
Year: 2021
Journal: Cell
Title: Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Volume: 184
Issue: 11
Pages: 2896-2910.e13
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Publication
15136728 | J:90654
First Author: Zhu Y
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells.
Volume: 101
Issue: 20
Pages: 7681-6
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Publication
19578372 | J:158142
First Author: Ishihara N
Year: 2009
Journal: Nat Cell Biol
Title: Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Volume: 11
Issue: 8
Pages: 958-66
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Publication
20436477 | J:209127
First Author: Zaltsman Y
Year: 2010
Journal: Nat Cell Biol
Title: MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Volume: 12
Issue: 6
Pages: 553-562
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Publication
38512414 | J:350675
First Author: Yu V
Year: 2024
Journal: Diabetologia
Title: Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.
Volume: 67
Issue: 6
Pages: 1079-1094
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Publication
25975226 | J:317793
First Author: De Zio D
Year: 2015
Journal: Cell Mol Life Sci
Title: Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.
Volume: 72
Issue: 21
Pages: 4173-91
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Publication
28595361 | J:243635
First Author: Khacho M
Year: 2017
Journal: Hum Mol Genet
Title: Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.
Volume: 26
Issue: 17
Pages: 3327-3341
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Publication
37342629 | J:359189
 
First Author: So HK
Year: 2023
Journal: Research (Wash D C)
Title: Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss.
Volume: 6
Pages: 0158
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Publication
12931191 | J:85083
First Author: Danial NN
Year: 2003
Journal: Nature
Title: BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis.
Volume: 424
Issue: 6951
Pages: 952-6
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Publication
27802136 | J:240472
First Author: Kumar N
Year: 2016
Journal: Development
Title: A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis.
Volume: 143
Issue: 20
Pages: 3711-3722
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Publication
28619824 | J:242895
First Author: Brici D
Year: 2017
Journal: Development
Title: Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.
Volume: 144
Issue: 14
Pages: 2606-2617
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Publication
30701202 | J:272251
 
First Author: Noguchi S
Year: 2019
Journal: Commun Biol
Title: Beclin 1 regulates recycling endosome and is required for skin development in mice.
Volume: 2
Pages: 37
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Publication
35794642 | J:339244
First Author: Chen X
Year: 2022
Journal: Cell Biosci
Title: Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function.
Volume: 12
Issue: 1
Pages: 103
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Publication
28188211 | J:249661
First Author: Schatton D
Year: 2017
Journal: J Cell Biol
Title: CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
Volume: 216
Issue: 3
Pages: 675-693
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Publication
28846746 | J:244992
First Author: Gomez-Velazquez M
Year: 2017
Journal: PLoS Genet
Title: CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Volume: 13
Issue: 8
Pages: e1006985
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Publication
27246713 | J:235665
First Author: He S
Year: 2016
Journal: Development
Title: Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.
Volume: 143
Issue: 11
Pages: 1937-47
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Publication
35099001 | J:324720
 
First Author: Zhao Q
Year: 2022
Journal: J Cell Sci
Title: Drp1 regulates transcription of ribosomal protein genes in embryonic hearts.
Volume: 135
Issue: 4
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Publication
27407143 | J:235155
First Author: Doucet-Beaupré H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Volume: 113
Issue: 30
Pages: E4387-96
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Publication
28465321 | J:356661
First Author: Esteban-Martínez L
Year: 2017
Journal: EMBO J
Title: Programmed mitophagy is essential for the glycolytic switch during cell differentiation.
Volume: 36
Issue: 12
Pages: 1688-1706
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Publication
39033542 | J:360967
First Author: Ma H
Year: 2024
Journal: Adv Sci (Weinh)
Title: Gasdermin D Mediated Mitochondrial Metabolism Orchestrate Neurogenesis Through LDHA During Embryonic Development.
Volume: 11
Issue: 35
Pages: e2402285
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Publication
30655546 | J:270211
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
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Publication
25348719 | J:224310
First Author: Ishihara T
Year: 2015
Journal: Mol Cell Biol
Title: Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Volume: 35
Issue: 1
Pages: 211-23
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Publication
37982452 | J:343798
 
First Author: Cheng T
Year: 2023
Journal: Development
Title: Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Volume: 150
Issue: 24
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Publication
37812701 | J:342544
First Author: Radzishevsky I
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Volume: 120
Issue: 42
Pages: e2302780120
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Publication
32376682 | J:290315
 
First Author: Cheong A
Year: 2020
Journal: Development
Title: Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation.
Volume: 147
Issue: 10
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Publication
38466355 | J:347414
 
First Author: Yang J
Year: 2024
Journal: J Clin Invest
Title: A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis.
Volume: 134
Issue: 8
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Publication
- | J:279207
     
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
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First Author: Okazaki N
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Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
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First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
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Journal: Cell
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First Author: Mouse Genome Informatics Scientific Curators
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First Author: The Jackson Laboratory
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First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
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First Author: The Gene Ontology Consortium
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First Author: Mouse Genome Informatics Scientific Curators
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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