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Search results 101 to 184 out of 184 for Tpcn1

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0.024s
Type Details Score
GXD Expression  
Probe: MGI:5293771
Assay Type: RNA in situ
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1795228
Pattern: Uniform
Stage: TS28
Assay Id: MGI:5293773
Age: postnatal
Note: Even expression throughout the renal cortex and medulla.
Specimen Label: S3B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619662
Specimen Label: JAX_1619662
Detected: true
Specimen Num: 31
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1920928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619622
Specimen Label: JAX_1619622
Detected: true
Specimen Num: 36
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619635
Specimen Label: JAX_1619635
Detected: true
Specimen Num: 49
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619658
Specimen Label: JAX_1619658
Detected: true
Specimen Num: 27
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619629
Specimen Label: JAX_1619629
Detected: true
Specimen Num: 43
GXD Expression  
Probe: MGI:5293771
Assay Type: RNA in situ
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1927928
Pattern: Uniform
Stage: TS28
Assay Id: MGI:5293773
Age: postnatal
Note: Even expression throughout the renal cortex and medulla.
Specimen Label: S3B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619637
Specimen Label: JAX_1619637
Detected: true
Specimen Num: 51
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619636
Specimen Label: JAX_1619636
Detected: true
Specimen Num: 50
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619634
Specimen Label: JAX_1619634
Detected: true
Specimen Num: 48
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619641
Specimen Label: JAX_1619641
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3271628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619648
Specimen Label: JAX_1619648
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619618
Specimen Label: JAX_1619618
Detected: true
Specimen Num: 32
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619649
Specimen Label: JAX_1619649
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619619
Specimen Label: JAX_1619619
Detected: true
Specimen Num: 33
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619654
Specimen Label: JAX_1619654
Detected: true
Specimen Num: 23
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619653
Specimen Label: JAX_1619653
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619620
Specimen Label: JAX_1619620
Detected: true
Specimen Num: 34
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619631
Specimen Label: JAX_1619631
Detected: true
Specimen Num: 45
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619645
Specimen Label: JAX_1619645
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619633
Specimen Label: JAX_1619633
Detected: true
Specimen Num: 47
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619652
Specimen Label: JAX_1619652
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:5293771
Assay Type: RNA in situ
Annotation Date: 2011-10-28
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5293773
Age: postnatal
Note: Moderate expression in most part of the brain.
Specimen Label: S3A
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619661
Specimen Label: JAX_1619661
Detected: true
Specimen Num: 30
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619656
Specimen Label: JAX_1619656
Detected: true
Specimen Num: 25
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692514
Age: postnatal adult
Image: JAX_1619621
Specimen Label: JAX_1619621
Detected: true
Specimen Num: 35
Strain
Attribute String: mutant stock, targeted mutation
Publication
First Author: Cang C
Year: 2014
Journal: Nat Chem Biol
Title: The voltage-gated sodium channel TPC1 confers endolysosomal excitability.
Volume: 10
Issue: 6
Pages: 463-9
Publication
First Author: Sakurai Y
Year: 2015
Journal: Science
Title: Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.
Volume: 347
Issue: 6225
Pages: 995-8
Publication
First Author: Zong X
Year: 2009
Journal: Pflugers Arch
Title: The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores.
Volume: 458
Issue: 5
Pages: 891-9
Publication
First Author: Arredouani A
Year: 2015
Journal: J Biol Chem
Title: Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.
Volume: 290
Issue: 35
Pages: 21376-92
Publication  
First Author: Royer J
Year: 2022
Journal: Biomedicines
Title: Unexpected Motherhood-Triggered Hearing Loss in the Two-Pore Channel (TPC) Mutant Mouse.
Volume: 10
Issue: 7
Publication
First Author: Lear PV
Year: 2015
Journal: Endocrinology
Title: Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.
Volume: 156
Issue: 3
Pages: 975-86
Publication  
First Author: de Zélicourt A
Year: 2024
Journal: Cell Calcium
Title: Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling.
Volume: 117
Pages: 102839
Publication
First Author: Capel RA
Year: 2015
Journal: J Biol Chem
Title: Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart.
Volume: 290
Issue: 50
Pages: 30087-98
Publication  
First Author: Foster WJ
Year: 2018
Journal: Sci Signal
Title: Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling.
Volume: 11
Issue: 558
Publication
First Author: Castonguay J
Year: 2017
Journal: Sci Rep
Title: The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes.
Volume: 7
Issue: 1
Pages: 10038
Publication
First Author: Wang X
Year: 2012
Journal: Cell
Title: TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.
Volume: 151
Issue: 2
Pages: 372-83
Publication
First Author: Cang C
Year: 2013
Journal: Cell
Title: mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.
Volume: 152
Issue: 4
Pages: 778-790
Publication
First Author: Freeman SA
Year: 2020
Journal: Science
Title: Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance.
Volume: 367
Issue: 6475
Pages: 301-305
Publication
First Author: Shigeto M
Year: 2015
Journal: J Clin Invest
Title: GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Volume: 125
Issue: 12
Pages: 4714-28
Publication
First Author: Davis LC
Year: 2020
Journal: EMBO J
Title: NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca(2+) nanodomains, calcineurin and dynamin.
Volume: 39
Issue: 14
Pages: e104058
Publication
First Author: Favia A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.
Volume: 111
Issue: 44
Pages: E4706-15
Publication  
First Author: Neely Kayala KM
Year: 2012
Journal: Brain Res
Title: Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function.
Volume: 1489
Pages: 8-16
Publication  
First Author: Diercks BP
Year: 2018
Journal: Sci Signal
Title: ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Volume: 11
Issue: 561
Publication
First Author: Perelygin AA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning of the murine flavivirus resistance gene.
Volume: 99
Issue: 14
Pages: 9322-7
Publication
First Author: Yu X
Year: 2006
Journal: J Immunol
Title: Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.
Volume: 177
Issue: 10
Pages: 7042-9
Publication
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
Publication
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Cane MC
Year: 2016
Journal: Cell Calcium
Title: The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion.
Volume: 59
Issue: 1
Pages: 32-40