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Search results 101 to 115 out of 115 for Tprn

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Type Details Score
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Tprn<em1Pghu> | MGI:5897817
Name: taperin; endonuclease-mediated mutation 1, Peng Hu
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tprn/Tprn
Background: B6.Cg-Tprn
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110526 | autosomal recessive nonsyndromic deafness 79
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Protein Domain
IPR026671 | PPP1R18/Tprn
Type: Family
Description: This entry includes Phostensin and Taperin. Phostensin binds to actin and decreases the elongation and depolymerisation rates of actin filament pointed ends []. Phostensin interacts with Protein phosphatase 1 (PP1). It is likely that phostensin targets PP1 to the F-actin cytoskeleton []. Taperin (TPRN) is also a PP1 binding protein that is ancestrally related tophostensin. It localised prominently at the taper regions of hair cell stereocilia and has a role in sound perception []. Defects in human TPRN are the cause of deafness autosomal recessive type 79 (DFNB79). DFNB79 is characterised by progressive hearing loss leading to profound deafness. There are no symptoms of vestibular dysfunction [, ].
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Protein
Q3U3A9
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Protein
A0A087WRI9
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: false
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Protein
Q8BQ30
Organism: Mus musculus/domesticus
Length: 594  
Fragment?: false
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Protein
B7ZND7
Organism: Mus musculus/domesticus
Length: 594  
Fragment?: false
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Protein
B2RWV7
Organism: Mus musculus/domesticus
Length: 594  
Fragment?: false
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Publication
17374523 | -
First Author: Kao SC
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit.
Volume: 356
Issue: 3
Pages: 594-8
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Publication
19622346 | -
First Author: Lai NS
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Phostensin caps to the pointed end of actin filaments and modulates actin dynamics.
Volume: 387
Issue: 4
Pages: 676-81
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