Type |
Details |
Score |
Publication |
First Author: |
Kuchroo VK |
Year: |
1994 |
Journal: |
J Exp Med |
Title: |
T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. |
Volume: |
179 |
Issue: |
5 |
Pages: |
1659-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Becker DM |
Year: |
1985 |
Journal: |
Nature |
Title: |
Variability and repertoire size of T-cell receptor V alpha gene segments. |
Volume: |
317 |
Issue: |
6036 |
Pages: |
430-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winoto A |
Year: |
1985 |
Journal: |
Nature |
Title: |
Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. |
Volume: |
316 |
Issue: |
6031 |
Pages: |
832-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwanami N |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells. |
Volume: |
14 |
Issue: |
1 |
Pages: |
3645 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hue I |
Year: |
1990 |
Journal: |
J Immunol |
Title: |
A novel type of aberrant T cell receptor alpha-chain gene rearrangement. Implications for allelic exclusion and the V-J recombination process. |
Volume: |
144 |
Issue: |
11 |
Pages: |
4410-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Epstein R |
Year: |
1986 |
Journal: |
J Exp Med |
Title: |
The cytotoxic T cell response to the male-specific histocompatibility antigen (H-Y) is controlled by two dominant immune response genes, one in the MHC, the other in the Tar alpha-locus. |
Volume: |
163 |
Issue: |
4 |
Pages: |
759-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Danska JS |
Year: |
1990 |
Journal: |
J Exp Med |
Title: |
The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides. |
Volume: |
172 |
Issue: |
1 |
Pages: |
27-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gleditsch L |
Year: |
1990 |
Journal: |
Immunogenetics |
Title: |
No recombinations between Tcra-V and Tcra-C gene segments in 669 backcross mice. |
Volume: |
32 |
Issue: |
5 |
Pages: |
297-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang XX |
Year: |
1994 |
Journal: |
Mol Immunol |
Title: |
Nucleotide sequences of three new members of the mouse V alpha 2 gene family. |
Volume: |
31 |
Issue: |
1 |
Pages: |
78-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koop BF |
Year: |
1994 |
Journal: |
Nat Genet |
Title: |
Striking sequence similarity over almost 100 kilobases of human and mouse T-cell receptor DNA. |
Volume: |
7 |
Issue: |
1 |
Pages: |
48-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fink PJ |
Year: |
1986 |
Journal: |
Nature |
Title: |
Correlations between T-cell specificity and the structure of the antigen receptor. |
Volume: |
321 |
Issue: |
6067 |
Pages: |
219-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Malissen M |
Year: |
1988 |
Journal: |
Cell |
Title: |
A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition. |
Volume: |
55 |
Issue: |
1 |
Pages: |
49-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yague J |
Year: |
1988 |
Journal: |
Nucleic Acids Res |
Title: |
The structure of V alpha and J alpha segments in the mouse. |
Volume: |
16 |
Issue: |
23 |
Pages: |
11355-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jouvin-Marche E |
Year: |
1989 |
Journal: |
Immunogenetics |
Title: |
Complexity, polymorphism, and recombination of mouse T-cell receptor alpha gene families. |
Volume: |
30 |
Issue: |
2 |
Pages: |
99-104 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang K |
Year: |
1994 |
Journal: |
Immunogenetics |
Title: |
The expression of mouse T-cell receptor TCRDV genes in BALB/c spleen. |
Volume: |
40 |
Issue: |
4 |
Pages: |
271-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsu BL |
Year: |
1996 |
Journal: |
J Immunol |
Title: |
TCR recognition of the Hb(64-76)/I-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity. |
Volume: |
157 |
Issue: |
6 |
Pages: |
2291-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshikai Y |
Year: |
1986 |
Journal: |
Nature |
Title: |
Athymic mice express a high level of functional gamma-chain but greatly reduced levels of alpha- and beta-chain T-cell receptor messages. |
Volume: |
324 |
Issue: |
6096 |
Pages: |
482-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chou HS |
Year: |
1986 |
Journal: |
EMBO J |
Title: |
T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments. |
Volume: |
5 |
Issue: |
9 |
Pages: |
2149-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gleditsch L |
Year: |
1992 |
Journal: |
Immunogenetics |
Title: |
A Tcra congenic mouse: V alpha epitope expression is influenced by both Tcra haplotypes and background genes. |
Volume: |
35 |
Issue: |
3 |
Pages: |
153-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Freeman TC |
Year: |
1998 |
Journal: |
MGI Direct Data Submission |
Title: |
Expression Mapping of Mouse Genes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Giudicelli V |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. |
Volume: |
33 |
Issue: |
Database issue |
Pages: |
D256-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The proteins in this entry are found in the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The proteins contain the Walker A and B motifs and so are putative nucleotide triphosphatases [, ]. |
|
•
•
•
•
•
|
Allele |
Name: |
T cell receptor alpha constant; endonuclease-mediated mutation 1, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
González-Rivera C |
Year: |
2019 |
Journal: |
Mol Microbiol |
Title: |
Two pKM101-encoded proteins, the pilus-tip protein TraC and Pep, assemble on the Escherichia coli cell surface as adhesins required for efficient conjugative DNA transfer. |
Volume: |
111 |
Issue: |
1 |
Pages: |
96-117 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Leung A |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Persistent Chromatin Modifications Induced by High Fat Diet. |
Volume: |
291 |
Issue: |
20 |
Pages: |
10446-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Costello KR |
Year: |
2021 |
Journal: |
Elife |
Title: |
Sequence features of retrotransposons allow for epigenetic variability. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6715367 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-06-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6715546 |
Age: |
embryonic day 10.5 |
|
Note: |
Number of cardiomyocytes in outflow trac and right ventricle were similar betwen control and mutant embryos at E9.5 and E10.5. |
Specimen Label: |
E10.5 CTL not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6715367 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-06-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6715546 |
Age: |
embryonic day 10.5 |
|
Note: |
Number of cardiomyocytes in outflow trac and right ventricle were similar betwen control and mutant embryos at E9.5 and E10.5. |
Specimen Label: |
E10.5 shfKO not shown |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6715367 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-06-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6715546 |
Age: |
embryonic day 10.5 |
|
Note: |
Number of cardiomyocytes in outflow trac and right ventricle were similar betwen control and mutant embryos at E9.5 and E10.5. |
Specimen Label: |
E10.5 CTL not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6715367 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-06-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6715546 |
Age: |
embryonic day 10.5 |
|
Note: |
Number of cardiomyocytes in outflow trac and right ventricle were similar betwen control and mutant embryos at E9.5 and E10.5. |
Specimen Label: |
E10.5 shfKO not shown |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leung A |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat diet. |
Volume: |
289 |
Issue: |
34 |
Pages: |
23557-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miele L |
Year: |
1991 |
Journal: |
DNA Seq |
Title: |
Gene organization and nucleotide sequence of the primase region of IncP plasmids RP4 and R751. |
Volume: |
2 |
Issue: |
3 |
Pages: |
145-62 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This is a domain of unknown function which can be found in DNA primases such as TraC []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2253
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawley TD |
Year: |
2003 |
Journal: |
FEMS Microbiol Lett |
Title: |
F factor conjugation is a true type IV secretion system. |
Volume: |
224 |
Issue: |
1 |
Pages: |
1-15 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a central domain found in the type IV secretion system protein TraC from Escherichia coli (strain K12). TraC is required for the assembly of mature F-pilin subunits into extended F pili, thus involved in bacterial conjugation [, ]. This domain is mainly found in proteins from Proteobacteria, and is approximately 170 amino acids in length. It is found in association with PF11130. There are two conserved sequence motifs: GWDL and QGEY. |
|
•
•
•
•
•
|
Publication |
First Author: |
Frost LS |
Year: |
2005 |
Journal: |
Nat Rev Microbiol |
Title: |
Mobile genetic elements: the agents of open source evolution. |
Volume: |
3 |
Issue: |
9 |
Pages: |
722-32 |
|
•
•
•
•
•
|
Allele |
Name: |
T cell receptor alpha constant; endonuclease-mediated mutation 1, Ingunn Stromnes |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
T cell receptor alpha constant; endonuclease-mediated mutation 2, Ingunn Stromnes |
|
Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Yuan Q |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Identification of the VirB4-VirB8-VirB5-VirB2 pilus assembly sequence of type IV secretion systems. |
Volume: |
280 |
Issue: |
28 |
Pages: |
26349-59 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry contains VirB5, a protein that is involved in the type IV DNA secretion systems typified by the Agrobacterium Ti plasmid vir system where it interacts with several other proteins essential for proper pilus formation []. VirB5 is homologous to the IncN (N-type) conjugation system protein TraC []as well as the P-type protein TrbJ and the F-type protein TraE []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Schandel KA |
Year: |
1992 |
Journal: |
J Bacteriol |
Title: |
Localization of TraC, a protein involved in assembly of the F conjugative pilus. |
Volume: |
174 |
Issue: |
11 |
Pages: |
3800-6 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeo HJ |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101. |
Volume: |
100 |
Issue: |
26 |
Pages: |
15947-52 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This family of TraC-related proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process []. This family also includes predicted ATPases associated with DNA conjugal transfer. These are found both in plasmids and in bacterial chromosomal regions that appear to derive from integrative elements such as conjugative transposons. |
|
•
•
•
•
•
|
Publication |
First Author: |
Chase TH |
Year: |
2010 |
Journal: |
Blood |
Title: |
The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia. |
Volume: |
115 |
Issue: |
6 |
Pages: |
1267-76 |
|
•
•
•
•
•
|