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Search results 101 to 149 out of 149 for Trap1

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Type Details Score
Protein
Q922Z3
Organism: Mus musculus/domesticus
Length: 705  
Fragment?: true
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Publication
- | J:360705
     
First Author: Rydzanicz M
Year: 2023
Journal: bioRxiv
Title: Mutation in mitochondrial chaperone TRAP1 results in male-specific autism.
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Publication
36065186 | J:347547
First Author: Chen FW
Year: 2022
Journal: iScience
Title: Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.
Volume: 25
Issue: 9
Pages: 104941
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Publication
33746957 | J:308248
 
First Author: Felux J
Year: 2021
Journal: Front Immunol
Title: Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus.
Volume: 12
Pages: 613597
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Publication
27216192 | J:234847
First Author: Rizza S
Year: 2016
Journal: Cancer Res
Title: S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase.
Volume: 76
Issue: 14
Pages: 4170-82
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Protein
Q3UR70
Organism: Mus musculus/domesticus
Length: 860  
Fragment?: false
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Protein
Q3UR70-2
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Allele
Trap1<em1Smoc> | MGI:7292950
Name: TNF receptor-associated protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Trap1<em2Smoc> | MGI:7292951
Name: TNF receptor-associated protein 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Trap1<em3Smoc> | MGI:7292952
Name: TNF receptor-associated protein 1; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Strain
MGI:6771234 | C57BL/6JSmoc-Trap1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7623521 | C57BL/6JSmoc-Trap1<em3Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
30758851 | J:277126
First Author: Kenny EF
Year: 2019
Journal: Eur J Immunol
Title: Dnase1-deficient mice spontaneously develop a systemic lupus erythematosus-like disease.
Volume: 49
Issue: 4
Pages: 590-599
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Allele
Dnase1<tm2092.1Arte> | MGI:6400348
Name: deoxyribonuclease I; targeted mutation 2092.1, TaconicArtemis
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Dnase1/Dnase1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR019452 | VPS39/TGF_beta_rcpt-assoc_1
Type: Domain
Description: This entry represents a domain found in the vacuolar sorting protein Vps39 and transforming growth factor beta receptor-associated protein Trap1. Vps39, a component of the C-Vps complex, is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole [, ]. In Saccharomyces cerevisiae (Baker's yeast), Vps39 has been shown to stimulate nucleotide exchange []. Trap1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling [, ]. The precise function of this domain has not been characterised.
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Publication
1493335 | -
First Author: Raymond CK
Year: 1992
Journal: Mol Biol Cell
Title: Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants.
Volume: 3
Issue: 12
Pages: 1389-402
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Publication
11062257 | -
First Author: Wurmser AE
Year: 2000
Journal: J Cell Biol
Title: New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion.
Volume: 151
Issue: 3
Pages: 551-62
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Publication
9545258 | -
First Author: Charng MJ
Year: 1998
Journal: J Biol Chem
Title: A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor.
Volume: 273
Issue: 16
Pages: 9365-8
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Publication
11278302 | -
First Author: Wurthner JU
Year: 2001
Journal: J Biol Chem
Title: Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone.
Volume: 276
Issue: 22
Pages: 19495-502
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Publication
20961651 | J:312182
First Author: Messler S
Year: 2011
Journal: Immunobiology
Title: The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.
Volume: 216
Issue: 3
Pages: 343-50
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Protein Domain
IPR019453 | VPS39/TGF_beta_rcpt-assoc_2
Type: Domain
Description: This entry represents a domain found in the vacuolar sorting protein Vps39 and transforming growth factor beta receptor-associated protein Trap1. Vps39, a component of the C-Vps complex, is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole [, ]. In Saccharomyces cerevisiae (Baker's yeast), Vps39 has been shown to stimulate nucleotide exchange []. Trap1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling [, ]. The precise function of this domain has not been characterised In Vps39 this domain is involved in localisation and in mediating the interactions with Vps11 [].
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Allele
Dnase1<tm1Tmo> | MGI:2387029
Name: deoxyribonuclease I; targeted mutation 1, Tarik Moroy
Allele Type: Targeted
Attribute String: Null/knockout
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Protein
A0A087WQF3
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Publication
10835632 | J:62549
First Author: Napirei M
Year: 2000
Journal: Nat Genet
Title: Features of systemic lupus erythematosus in Dnase1-deficient mice.
Volume: 25
Issue: 2
Pages: 177-81
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Publication
15015938 | J:113757
First Author: Napirei M
Year: 2004
Journal: Biochem J
Title: Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse.
Volume: 380
Issue: Pt 3
Pages: 929-37
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Publication
29191910 | J:252490
First Author: Jiménez-Alcázar M
Year: 2017
Journal: Science
Title: Host DNases prevent vascular occlusion by neutrophil extracellular traps.
Volume: 358
Issue: 6367
Pages: 1202-1206
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Publication
15796714 | J:117500
First Author: Napirei M
Year: 2005
Journal: Biochem J
Title: Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3).
Volume: 389
Issue: Pt 2
Pages: 355-64
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Publication
19154352 | J:147888
First Author: Napirei M
Year: 2009
Journal: FEBS J
Title: Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).
Volume: 276
Issue: 4
Pages: 1059-73
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Publication
37287977 | J:346926
 
First Author: Englert H
Year: 2023
Journal: Front Immunol
Title: Targeting NETs using dual-active DNase1 variants.
Volume: 14
Pages: 1181761
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Publication
15647342 | J:110060
First Author: Basnakian AG
Year: 2005
Journal: J Am Soc Nephrol
Title: Cisplatin nephrotoxicity is mediated by deoxyribonuclease I.
Volume: 16
Issue: 3
Pages: 697-702
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Genotype
Genotype
Symbol: Dnase1/Dnase1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnase1/Dnase1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnase1/Dnase1
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: hm
Has Mutant Allele: true
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Publication
26100518 | J:296104
 
First Author: Lin PH
Year: 2015
Journal: J Biomed Sci
Title: N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting.
Volume: 22
Pages: 44
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Publication
9111041 | -
First Author: Nakamura N
Year: 1997
Journal: J Biol Chem
Title: Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae.
Volume: 272
Issue: 17
Pages: 11344-9
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Publication
19299707 | J:147129
First Author: Zikherman J
Year: 2009
Journal: J Immunol
Title: PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background.
Volume: 182
Issue: 7
Pages: 4093-106
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Publication
28743926 | J:257235
First Author: Fischer H
Year: 2017
Journal: Sci Rep
Title: Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis.
Volume: 7
Issue: 1
Pages: 6433
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Publication
27771328 | J:240052
First Author: Fischer H
Year: 2017
Journal: J Invest Dermatol
Title: Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death.
Volume: 137
Issue: 3
Pages: 587-594
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Publication
24335230 | J:209292
First Author: Rossaint J
Year: 2014
Journal: Blood
Title: Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation.
Volume: 123
Issue: 16
Pages: 2573-84
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Protein
Q8R5L3
Organism: Mus musculus/domesticus
Length: 886  
Fragment?: false
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Protein
Q6ZQ51
Organism: Mus musculus/domesticus
Length: 889  
Fragment?: true
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Protein
Q3USV9
Organism: Mus musculus/domesticus
Length: 886  
Fragment?: false
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Protein
Q3TC98
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: false
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Protein
Q8BY36
Organism: Mus musculus/domesticus
Length: 875  
Fragment?: false
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Protein
Q3URK7
Organism: Mus musculus/domesticus
Length: 875  
Fragment?: false
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Protein
Q5KU38
Organism: Mus musculus/domesticus
Length: 875  
Fragment?: false
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Protein
Q8BUJ2
Organism: Mus musculus/domesticus
Length: 799  
Fragment?: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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