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Search results 101 to 154 out of 154 for Trim30d

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Details

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Publication

34289368 | J:334263

First Author:	Gaikwad S
Year:	2021
Journal:	Cell Rep
Title:	Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia.
Volume:	36
Issue:	3
Pages:	109419

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Publication

15930395 | J:98717

First Author:	Andorfer C
Year:	2005
Journal:	J Neurosci
Title:	Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.
Volume:	25
Issue:	22
Pages:	5446-54

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Publication

29175372 | J:257585

First Author:	Rossi F
Year:	2018
Journal:	Behav Brain Res
Title:	NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy.
Volume:	339

Pages:	140-152

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Publication

29037207 | J:285524

First Author:	Bemiller SM
Year:	2017
Journal:	Mol Neurodegener
Title:	TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Volume:	12
Issue:	1
Pages:	74

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Publication

35202653 | J:353256

First Author:	Puangmalai N
Year:	2022
Journal:	J Biol Chem
Title:	Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer's disease.
Volume:	298
Issue:	4
Pages:	101766

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Publication

27565300 | J:239559

First Author:	Gratuze M
Year:	2016
Journal:	Neurobiol Aging
Title:	High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology.
Volume:	47

Pages:	71-73

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Publication

34874917 | J:353255

First Author:	Ezerskiy LA
Year:	2022
Journal:	JCI Insight
Title:	Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction.
Volume:	7
Issue:	1

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Publication

34029610 | J:353257

First Author:	Cloyd RA
Year:	2021
Journal:	Exp Neurol
Title:	Effects of altered tau expression on dentate granule cell excitability in mice.
Volume:	343

Pages:	113766

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Publication

28472990 | J:318436

First Author:	Chai GS
Year:	2017
Journal:	Mol Neurodegener
Title:	Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.
Volume:	12
Issue:	1
Pages:	34

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Publication

37009893 | J:334929

First Author:	Khan KM
Year:	2023
Journal:	Acta Neuropathol Commun
Title:	Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease.
Volume:	11
Issue:	1
Pages:	57

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Publication

35359570 | J:322798

First Author:	Trease AJ
Year:	2022
Journal:	Front Mol Neurosci
Title:	Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy.
Volume:	15

Pages:	852368

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Publication

32572268 | J:337331

First Author:	Dujardin S
Year:	2020
Journal:	Nat Med
Title:	Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Volume:	26
Issue:	8
Pages:	1256-1263

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Genotype

Symbol:	Mapt/Mapt Tg(MAPT)8cPdav/?
Background:	involves: 129S4/SvJae * C57BL/6 * Swiss Webster
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mapt/Mapt Tg(MAPT)8cPdav/?
Background:	B6.Cg-Tg(MAPT)8cPdav Mapt/J
Zygosity:	cx
Has Mutant Allele:	true

•

Strain

MGI:5581709 | B6.Cg-Tg(MAPT)8cPdav Psen1<tm1Mpm> App<tm1Ck>

Attribute String:

targeted mutation, transgenic, mutant strain, congenic

•

Publication

24278307 | J:209782

First Author:	Guo Q
Year:	2013
Journal:	PLoS One
Title:	Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau.
Volume:	8
Issue:	11
Pages:	e80706

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Publication

35045281 | J:327028

First Author:	Qureshi YH
Year:	2022
Journal:	Cell Rep
Title:	The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease.
Volume:	38
Issue:	3
Pages:	110262

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Publication

27974048 | J:285085

First Author:	Maphis N
Year:	2016
Journal:	Alzheimers Res Ther
Title:	Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.
Volume:	8
Issue:	1
Pages:	54

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Publication

28367114 | J:284907

First Author:	Maphis NM
Year:	2017
Journal:	Front Mol Neurosci
Title:	Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.
Volume:	10

Pages:	69

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Publication

25863528 | J:222621

First Author:	Komuro Y
Year:	2015
Journal:	Neurobiol Aging
Title:	Human tau expression reduces adult neurogenesis in a mouse model of tauopathy.
Volume:	36
Issue:	6
Pages:	2034-42

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Publication

32829029 | J:304391

First Author:	Race B
Year:	2020
Journal:	Neurobiol Dis
Title:	Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein.
Volume:	144

Pages:	105057

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Publication

30253780 | J:267673

First Author:	Bemiller SM
Year:	2018
Journal:	J Neuroinflammation
Title:	Genetically enhancing the expression of chemokine domain of CX₃CL1 fails to prevent tau pathology in mouse models of tauopathy.
Volume:	15
Issue:	1
Pages:	278

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Publication

27676333 | J:239562

First Author:	Rosa E
Year:	2016
Journal:	Neurobiol Aging
Title:	Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.
Volume:	48

Pages:	135-142

•

Publication

21147995 | J:166739

First Author:	Boutajangout A
Year:	2010
Journal:	J Neurosci
Title:	Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model.
Volume:	30
Issue:	49
Pages:	16559-66

•

Publication

30915013 | J:311096

First Author:	Rubenstein R
Year:	2019
Journal:	Front Neurol
Title:	Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation.
Volume:	10

Pages:	124

•

Publication

26311071 | J:229560

First Author:	Xu L
Year:	2015
Journal:	Exp Neurol
Title:	Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Volume:	273

Pages:	168-76

•

Publication

31085626 | J:276872

First Author:	Li XG
Year:	2019
Journal:	EMBO Rep
Title:	Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.
Volume:	20
Issue:	6

•

Publication

30373880 | J:269026

First Author:	Wang ZH
Year:	2018
Journal:	J Exp Med
Title:	Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies.
Volume:	215
Issue:	12
Pages:	3038-3056

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Publication

38192302 | J:348759

First Author:	Vemula P
Year:	2023
Journal:	Front Mol Neurosci
Title:	Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo.
Volume:	16

Pages:	1320182

•

Publication

17517623 | J:259130

First Author:	Luo W
Year:	2007
Journal:	Proc Natl Acad Sci U S A
Title:	Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Volume:	104
Issue:	22
Pages:	9511-6

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Publication

33311478 | J:306682

First Author:	Wu Z
Year:	2020
Journal:	Cell Death Dis
Title:	Delta-secretase triggers Alzheimer's disease pathologies in wild-type hAPP/hMAPT double transgenic mice.
Volume:	11
Issue:	12
Pages:	1058

•

Genotype

Symbol:	App/App Psen1/Psen1 Tg(MAPT)8cPdav/?
Background:	B6.Cg-Tg(MAPT)8cPdav Psen1 App
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

27629715 | J:240514

First Author:	Sherman MA
Year:	2016
Journal:	J Neurosci
Title:	Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Volume:	36
Issue:	37
Pages:	9647-58

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Publication

33383188 | J:353250

First Author:	Ojo J
Year:	2021
Journal:	Neurobiol Dis
Title:	Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma.
Volume:	150

Pages:	105237

•

Publication

32778161 | J:353258

First Author:	Farmer KM
Year:	2020
Journal:	Acta Neuropathol Commun
Title:	P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease.
Volume:	8
Issue:	1
Pages:	132

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Publication

33482356 | J:307763

First Author:	Marquez A
Year:	2021
Journal:	Neurobiol Dis
Title:	Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
Volume:	151

Pages:	105273

•

Publication

35082119 | J:353267

First Author:	Gerson JE
Year:	2022
Journal:	J Neurosci
Title:	Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy.
Volume:	42
Issue:	9
Pages:	1845-1863

•

Publication

21573167 | J:172426

First Author:	Phillips M
Year:	2011
Journal:	PLoS One
Title:	Olfactory and visuospatial learning and memory performance in two strains of Alzheimer's disease model mice--a longitudinal study.
Volume:	6
Issue:	5
Pages:	e19567

•

Publication

27070146 | J:253550

First Author:	Yetman MJ
Year:	2016
Journal:	PLoS One
Title:	Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction.
Volume:	11
Issue:	4
Pages:	e0153724

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Publication

32039516 | J:292621

First Author:	Zhu K
Year:	2020
Journal:	Glia
Title:	Absence of microglia or presence of peripherally-derived macrophages does not affect tau pathology in young or old hTau mice.
Volume:	68
Issue:	7
Pages:	1466-1478

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Publication

38131009 | J:343622

First Author:	Wang Y
Year:	2023
Journal:	Front Aging Neurosci
Title:	A tau fragment links depressive-like behaviors and cognitive declines in Alzheimer's disease mouse models through attenuating mitochondrial function.
Volume:	15

Pages:	1293164

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Publication

33859747 | J:348495

First Author:	Wang W
Year:	2021
Journal:	Theranostics
Title:	A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models.
Volume:	11
Issue:	11
Pages:	5279-5295

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Publication

30120733 | J:285073

First Author:	Comerota MM
Year:	2019
Journal:	Mol Neurobiol
Title:	Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies.
Volume:	56
Issue:	5
Pages:	3341-3355

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Publication

33895869 | J:355627

First Author:	Kang SS
Year:	2021
Journal:	Acta Neuropathol
Title:	ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease.
Volume:	142
Issue:	1
Pages:	139-158

•

Publication

35858909 | J:326808

First Author:	Hausrat TJ
Year:	2022
Journal:	Nat Commun
Title:	Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice.
Volume:	13
Issue:	1
Pages:	4192

•

Publication

30290707 | J:310931

First Author:	Xu Y
Year:	2019
Journal:	Autophagy
Title:	The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Volume:	15
Issue:	4
Pages:	583-598

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Publication

32603655 | J:301432

First Author:	Roussarie JP
Year:	2020
Journal:	Neuron
Title:	Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis.
Volume:	107
Issue:	5
Pages:	821-835.e12

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Publication

34551296 | J:327010

First Author:	Jiang S
Year:	2021
Journal:	Cell Rep
Title:	Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Volume:	36
Issue:	12
Pages:	109720

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Publication

31793911 | J:355611

First Author:	Kang SS
Year:	2020
Journal:	J Clin Invest
Title:	Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
Volume:	130
Issue:	1
Pages:	422-437

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Publication

35339896 | J:322782

First Author:	Zhou Q
Year:	2022
Journal:	EBioMedicine
Title:	Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration.
Volume:	78

Pages:	103970

•

Publication

19041304 | J:174270

First Author:	Levine S
Year:	2009
Journal:	Exp Mol Pathol
Title:	Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume:	86
Issue:	1
Pages:	18-22

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Publication

22687952 | J:207068

First Author:	Pozueta J
Year:	2013
Journal:	Neuroscience
Title:	Synaptic changes in Alzheimer's disease and its models.
Volume:	251

Pages:	51-65

•

Publication

36763499 | J:333453

First Author:	Moayedi Y
Year:	2023
Journal:	Cell Rep
Title:	The cellular basis of mechanosensation in mammalian tongue.
Volume:	42
Issue:	2
Pages:	112087

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Publication

30659012 | J:276927

First Author:	Goodwin LO
Year:	2019
Journal:	Genome Res
Title:	Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis.
Volume:	29
Issue:	3
Pages:	494-505

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