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Search results 101 to 200 out of 201 for Trim36

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Type Details Score
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_13
Specimen Label: euxassay_012029_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_14
Specimen Label: euxassay_012029_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_15
Specimen Label: euxassay_012029_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_16
Specimen Label: euxassay_012029_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_17
Specimen Label: euxassay_012029_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_02
Specimen Label: euxassay_012029_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_03
Specimen Label: euxassay_012029_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_04
Specimen Label: euxassay_012029_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_05
Specimen Label: euxassay_012029_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_06
Specimen Label: euxassay_012029_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_07
Specimen Label: euxassay_012029_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_08
Specimen Label: euxassay_012029_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_17
Specimen Label: euxassay_012029_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_18
Specimen Label: euxassay_012029_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_19
Specimen Label: euxassay_012029_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_20
Specimen Label: euxassay_012029_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_21
Specimen Label: euxassay_012029_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_04
Specimen Label: euxassay_012029_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_20
Specimen Label: euxassay_012029_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532521
Age: embryonic day 14.5
Note: Encoded in table as 'OB'.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_12
Specimen Label: euxassay_012029_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_15
Specimen Label: euxassay_012029_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_06
Specimen Label: euxassay_012029_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_07
Specimen Label: euxassay_012029_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_17
Specimen Label: euxassay_012029_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_18
Specimen Label: euxassay_012029_18
Detected: true
Specimen Num: 18
GXD Expression
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_08
Note: facial motor nucleus
Specimen Label: euxassay_012029_08
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_09
Note: facial motor nucleus
Specimen Label: euxassay_012029_09
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_11
Note: facial motor nucleus
Specimen Label: euxassay_012029_11
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_15
Note: facial motor nucleus
Specimen Label: euxassay_012029_15
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_16
Note: facial motor nucleus
Specimen Label: euxassay_012029_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4416346
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828915
Age: embryonic day 14.5
Image: euxassay_012029_16
Specimen Label: euxassay_012029_16
Detected: true
Specimen Num: 16
Publication
First Author: van Beuningen SF
Year: 2015
Journal: Neuron
Title: TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.
Volume: 88
Issue: 6
Pages: 1208-26
Publication  
First Author: Suzuki A
Year: 2024
Journal: J Reprod Immunol
Title: Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice.
Volume: 163
Pages: 104252
Publication
First Author: Pandey RR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.
Volume: 110
Issue: 41
Pages: 16492-7
Publication
First Author: Zhang Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors.
Volume: 113
Issue: 27
Pages: 7557-62
Publication
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
Publication
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
Publication
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
Publication      
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase Trim36
Type: chain
End: 729
Publication
First Author: Liu X
Year: 2023
Journal: Adv Sci (Weinh)
Title: FOXA2 Suppression by TRIM36 Exerts Anti-Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4-Regulated Ferroptosis.
Volume: 10
Issue: 35
Pages: e2304521
Publication
First Author: Short KM
Year: 2006
Journal: J Biol Chem
Title: Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.
Volume: 281
Issue: 13
Pages: 8970-80
Allele
Name: tripartite motif-containing 36; targeted mutation 1, Hiromitsu Tanaka
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Trim36/Trim36
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Yoshigai E
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Trim36/Haprin plays a critical role in the arrangement of somites during Xenopus embryogenesis.
Volume: 378
Issue: 3
Pages: 428-32
Protein Domain
Type: Domain
Description: This domain, consisting of the distinct N-terminal PRY subdomain followed by the SPRY subdomain, is found at the C terminus of TRIM36. TRIM36 (also known as Haprin or RNF98) has a ubiquitin ligase activity and interacts with centromere protein-H, one of the kinetochore proteins. It has been shown that TRIM36 is potentially associated with chromosome segregation and that an excess of TRIM36 may cause chromosomal instability []. In Xenopus laevis, TRIM36 is expressed during early embryogenesis and plays an important role in the arrangement of somites during their formation [].
Publication
First Author: Wright KM
Year: 2016
Journal: FEBS J
Title: Solution structure of the microtubule-targeting COS domain of MID1.
Volume: 283
Issue: 16
Pages: 3089-102
Publication  
First Author: Zanchetta ME
Year: 2019
Journal: Front Physiol
Title: Emerging Roles of the TRIM E3 Ubiquitin Ligases MID1 and MID2 in Cytokinesis.
Volume: 10
Pages: 274
Protein Domain
Type: Domain
Description: This entry represents the COS domain found in the C-I subfamily of the tripartite motif (TRIM) family of E3 ubiquitin ligases.The C-1 subfamily includes MID1 (TRIM18), MID2 (TRIM1), TRIM9, TNL (TRIM67), TRIM36 and TRIFIC (TRIM46) [, , ]. The C-I subfamily contains C-terminal FNIII and B30.2 domains which are associated with microtubules [, ]. C-I subfamily members also contain a relatively conserved region of approximately 60 amino acids, termed the C-terminal subgroup One Signature (COS) domain []. The human Midline-1 (MID1) COS domain has a helix-loop-helix structure in which the N- and C-terminal ends are in close proximity []. Deletion of the human MID1 COS domain does not affect MID1 dimerisation but disrupts localisation to the microtubules [].The COS domain is also observed within the TRIM C-II subgroup, which consists of the MURF1-3 proteins that do not contain the FNIII and B30.2domains. MUF1-3 proteins are also associated with microtubules [].
Protein
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 400  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 705  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 715  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 736  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89