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Search results 101 to 200 out of 8113 for Trp53

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191506
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Trp53
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191506
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Trp53
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Trp53
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Trp53
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Trp53
Detected: true
Specimen Num: 7
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Publication
15467370 | J:93129
First Author: Ashley T
Year: 2004
Journal: Cytogenet Genome Res
Title: The mammalian mid-pachytene checkpoint: meiotic arrest in spermatocytes with a mutation in Atm alone or in combination with a Trp53 (p53) or Cdkn1a (p21/cip1) mutation.
Volume: 107
Issue: 3-4
Pages: 256-62
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Publication
23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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Publication
31148594 | J:310363
First Author: Tang J
Year: 2019
Journal: Lab Invest
Title: Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Volume: 99
Issue: 10
Pages: 1454-1469
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Publication
31152920 | J:289336
 
First Author: Wada T
Year: 2019
Journal: Leuk Res
Title: Lysine-specific demethylase 1 accelerates oncogenesis in p53 heterozygous mice via transcriptional repression of the residual Trp53 allele.
Volume: 82
Pages: 29-32
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Publication
23499052 | J:195346
First Author: Wu R
Year: 2013
Journal: Am J Pathol
Title: Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.
Volume: 182
Issue: 4
Pages: 1391-9
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Publication
21504908 | J:174241
First Author: Wiley LA
Year: 2011
Journal: Dis Model Mech
Title: The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.
Volume: 4
Issue: 4
Pages: 484-95
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Publication
32339497 | J:293289
First Author: Masuda N
Year: 2020
Journal: Am J Pathol
Title: Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates the Development of Basal Squamous-Like Invasive Bladder Cancer in the Chemical Carcinogenesis of Mouse Bladder.
Volume: 190
Issue: 8
Pages: 1752-1762
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Publication
18562080 | J:141774
First Author: Chen J
Year: 2008
Journal: Exp Hematol
Title: Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice.
Volume: 36
Issue: 10
Pages: 1236-43
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Publication
18923161 | J:145784
First Author: Jin XL
Year: 2009
Journal: Biol Reprod
Title: Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.
Volume: 80
Issue: 2
Pages: 286-94
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Publication
22044588 | J:183674
First Author: Hoshino A
Year: 2012
Journal: J Mol Cell Cardiol
Title: p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.
Volume: 52
Issue: 1
Pages: 175-84
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Publication
26740101 | J:316141
 
First Author: Chen Z
Year: 2016
Journal: J Hematol Oncol
Title: Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity.
Volume: 9
Pages: 2
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Publication
17093197 | J:121124
First Author: Li A
Year: 2007
Journal: Biol Reprod
Title: Culture of zygotes increases TRP53 [corrected] expression in B6 mouse embryos, which reduces embryo viability.
Volume: 76
Issue: 3
Pages: 362-7
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Publication
10525351 | J:58392
First Author: Jordan SA
Year: 1999
Journal: Dev Biol
Title: Deficiency of Trp53 rescues the male fertility defects of Kit(W-v) mice but has no effect on the survival of melanocytes and mast cells.
Volume: 215
Issue: 1
Pages: 78-90
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Publication
29474172 | J:264146
   
First Author: Ghosh S
Year: 2018
Journal: Elife
Title: Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice.
Volume: 7
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Publication
20935145 | J:167245
First Author: Kimata M
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.
Volume: 299
Issue: 6
Pages: H1908-16
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Publication
9519874 | J:46426
First Author: Li B
Year: 1998
Journal: Oncogene
Title: A transgenic mouse model for mammary carcinogenesis.
Volume: 16
Issue: 8
Pages: 997-1007
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Publication
31983610 | J:285699
First Author: Cheung EC
Year: 2020
Journal: Cancer Cell
Title: Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer.
Volume: 37
Issue: 2
Pages: 168-182.e4
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GXD Expression
GXD Expression
Probe: MGI:6383856
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6400915
Age: embryonic day 12.5
Image: 4E E12 mutant
Note: Significantly more cells upregulated Trp53 throughout the E12 Rnu11-null pallium compared with the control. Only 6.7% of Trp53-upregulating cells were also H2ax-immunopositive in the mutant pallium.
Specimen Label: 4E E12 mutant
Detected: true
Specimen Num: 4
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Publication
28079895 | J:271798
First Author: Lacey D
Year: 2017
Journal: Cell Death Dis
Title: TNF-induced chronic inflammation does not affect tumorigenesis driven by p53 loss.
Volume: 8
Issue: 1
Pages: e2550
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Publication
34466150 | J:310633
First Author: Machida Y
Year: 2021
Journal: Oncol Lett
Title: Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice.
Volume: 22
Issue: 4
Pages: 738
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Allele
Trp53<em2Mvw> | MGI:6199168
Name: transformation related protein 53; endonuclease-mediated mutation 2, Michael Wiles
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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ncRNA Gene
MGI:2673128 | Lncpint
Type: lncRNA_gene
Organism: mouse, laboratory
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Publication
21674502 | J:174216
First Author: Terzian T
Year: 2011
Journal: J Pathol
Title: Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.
Volume: 224
Issue: 4
Pages: 540-52
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Publication
28425994 | J:254425
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
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Publication
10431243 | J:56548
First Author: Zheng B
Year: 1999
Journal: Nat Genet
Title: Engineering a mouse balancer chromosome.
Volume: 22
Issue: 4
Pages: 375-8
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Publication
26247727 | J:312562
 
First Author: Lee P
Year: 2015
Journal: Cell Death Dis
Title: p53- and p73-independent activation of TIGAR expression in vivo.
Volume: 6
Pages: e1842
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Publication
29650758 | J:263682
First Author: Tang Y
Year: 2018
Journal: J Biol Chem
Title: The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC.
Volume: 293
Issue: 20
Pages: 7578-7591
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Publication
35441828 | J:324753
First Author: He X
Year: 2022
Journal: Physiol Rep
Title: TIGAR deficiency sensitizes angiotensin-II-induced renal fibrosis and glomerular injury.
Volume: 10
Issue: 8
Pages: e15234
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Publication
38397106 | J:345711
 
First Author: He X
Year: 2024
Journal: Int J Mol Sci
Title: TIGAR Deficiency Blunts Angiotensin-II-Induced Cardiac Hypertrophy in Mice.
Volume: 25
Issue: 4
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Publication
35621078 | J:335006
First Author: He X
Year: 2022
Journal: J Cell Physiol
Title: Knockout of TIGAR enhances myocardial phosphofructokinase activity and preserves diastolic function in heart failure.
Volume: 237
Issue: 8
Pages: 3317-3327
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Publication
30901275 | J:301977
First Author: Okawa Y
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Ablation of cardiac TIGAR preserves myocardial energetics and cardiac function in the pressure overload heart failure model.
Volume: 316
Issue: 6
Pages: H1366-H1377
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Publication
32946259 | J:299844
First Author: Yamanaka R
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: TIGAR reduces smooth muscle cell autophagy to prevent pulmonary hypertension.
Volume: 319
Issue: 5
Pages: H1087-H1096
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Publication
31404346 | J:303442
First Author: Machida Y
Year: 2019
Journal: J Toxicol Pathol
Title: Increased susceptibility to mammary carcinogenesis and an opposite trend in endometrium in Trp53 heterozygous knockout female mice by backcrossing the BALB/c strain onto the background C3H strain.
Volume: 32
Issue: 3
Pages: 197-203
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Publication
36012294 | J:327815
 
First Author: Beauchamp MC
Year: 2022
Journal: Int J Mol Sci
Title: Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion.
Volume: 23
Issue: 16
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Publication
28283467 | J:328028
First Author: Alothman SJ
Year: 2017
Journal: Cancer Prev Res (Phila)
Title: Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus.
Volume: 10
Issue: 4
Pages: 244-254
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Publication
30977208 | J:291315
First Author: Li X
Year: 2019
Journal: Stem Cells
Title: p53-TP53-Induced Glycolysis Regulator Mediated Glycolytic Suppression Attenuates DNA Damage and Genomic Instability in Fanconi Anemia Hematopoietic Stem Cells.
Volume: 37
Issue: 7
Pages: 937-947
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Publication
32839323 | J:296022
First Author: Zhao Q
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: KMT5c modulates adipocyte thermogenesis by regulating Trp53 expression.
Volume: 117
Issue: 36
Pages: 22413-22422
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Protein Coding Gene
MGI:2384933 | Wrap53
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16778087 | J:112187
First Author: Zhang Z
Year: 2006
Journal: Mol Cancer Res
Title: p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer.
Volume: 4
Issue: 6
Pages: 401-10
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Publication
18234966 | J:136024
First Author: Wang Y
Year: 2008
Journal: Mol Cancer Res
Title: Enhanced susceptibility to chemical induction of ovarian tumors in mice with a germ line p53 mutation.
Volume: 6
Issue: 1
Pages: 99-109
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Publication
21764851 | J:174756
First Author: Dooley AL
Year: 2011
Journal: Genes Dev
Title: Nuclear factor I/B is an oncogene in small cell lung cancer.
Volume: 25
Issue: 14
Pages: 1470-5
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Protein Coding Gene
MGI:2442752 | Tigar
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20174572 | J:157988
First Author: Blanco-Aparicio C
Year: 2010
Journal: PLoS One
Title: Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.
Volume: 5
Issue: 2
Pages: e9305
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Publication
19661312 | J:209263
First Author: Martínez-Cruz AB
Year: 2009
Journal: Anticancer Res
Title: Spontaneous tumor formation in Trp53-deficient epidermis mediated by chromosomal instability and inflammation.
Volume: 29
Issue: 8
Pages: 3035-42
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Publication
23727860 | J:203215
First Author: Lunardi A
Year: 2013
Journal: Nat Genet
Title: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.
Volume: 45
Issue: 7
Pages: 747-55
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Publication
26334721 | J:268858
First Author: Ishimura A
Year: 2016
Journal: Cell Tissue Res
Title: Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.
Volume: 363
Issue: 3
Pages: 723-33
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Publication
35212626 | J:323190
   
First Author: Guo T
Year: 2022
Journal: Elife
Title: KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.
Volume: 11
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Allele
Trp53<em2Ove> | MGI:6715215
Name: transformation related protein 53; endonuclease-mediated mutation 2, Paul A Overbeek
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag
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Allele
Trp53<em3(GAL4)Ove> | MGI:6715217
Name: transformation related protein 53; endonuclease-mediated mutation 3, Paul A Overbeek
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Publication
31611390 | J:282081
First Author: Lázaro S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.
Volume: 116
Issue: 44
Pages: 22300-22306
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Publication
16869758 | J:115156
 
First Author: Calbó J
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.
Volume: 70
Pages: 225-32
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Publication
35954335 | J:327351
 
First Author: Lázaro S
Year: 2022
Journal: Cancers (Basel)
Title: Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma.
Volume: 14
Issue: 15
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Publication
16079851 | J:100683
First Author: Chen Z
Year: 2005
Journal: Nature
Title: Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Volume: 436
Issue: 7051
Pages: 725-30
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Publication
23478020 | J:270364
First Author: Kaushansky A
Year: 2013
Journal: Cell Rep
Title: Suppression of host p53 is critical for Plasmodium liver-stage infection.
Volume: 3
Issue: 3
Pages: 630-7
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Publication
22165824 | J:312015
First Author: Sullivan JM
Year: 2012
Journal: Radiat Res
Title: p21 protects "Super p53" mice from the radiation-induced gastrointestinal syndrome.
Volume: 177
Issue: 3
Pages: 307-10
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Publication
12426394 | J:80311
First Author: García-Cao I
Year: 2002
Journal: EMBO J
Title: "Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally.
Volume: 21
Issue: 22
Pages: 6225-35
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Publication
27668660 | J:259337
First Author: Schmitt AM
Year: 2016
Journal: Nat Genet
Title: An inducible long noncoding RNA amplifies DNA damage signaling.
Volume: 48
Issue: 11
Pages: 1370-1376
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Publication
28608929 | J:247957
First Author: Zhai Y
Year: 2017
Journal: J Pathol
Title: High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Volume: 243
Issue: 1
Pages: 16-25
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Publication
29604291 | J:273105
First Author: Kimura Y
Year: 2018
Journal: Gastroenterology
Title: ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Volume: 155
Issue: 1
Pages: 194-209.e2
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Publication
27373156 | J:238585
First Author: Semenova EA
Year: 2016
Journal: Cell Rep
Title: Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients.
Volume: 16
Issue: 3
Pages: 631-43
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Publication
35681513 | J:325568
 
First Author: Marney CB
Year: 2022
Journal: Cells
Title: A Unique Spectrum of Spontaneous Tumors in Dino Knockout Mice Identifies Tissue-Specific Requirements for Tumor Suppression.
Volume: 11
Issue: 11
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Publication
23973961 | J:201057
First Author: Pant V
Year: 2013
Journal: Genes Dev
Title: The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.
Volume: 27
Issue: 17
Pages: 1857-67
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Publication
24522546 | J:207466
 
First Author: Reiling E
Year: 2014
Journal: Sci Rep
Title: Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition.
Volume: 4
Pages: 4091
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Publication
32998907 | J:297490
 
First Author: Fu DJ
Year: 2020
Journal: Dis Model Mech
Title: Cells expressing PAX8 are the main source of homeostatic regeneration of adult mouse endometrial epithelium and give rise to serous endometrial carcinoma.
Volume: 13
Issue: 10
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Publication
38994678 | J:360098
First Author: McDaniel JM
Year: 2024
Journal: Cancer Res Commun
Title: p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator.
Volume: 4
Issue: 8
Pages: 1991-2007
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Publication
23486187 | J:199542
First Author: Mutsaers AJ
Year: 2013
Journal: Bone
Title: Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.
Volume: 55
Issue: 1
Pages: 166-78
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Publication
34987057 | J:321472
First Author: Liu X
Year: 2022
Journal: Cancer Res
Title: Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability.
Volume: 82
Issue: 5
Pages: 791-804
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Publication
37967175 | J:358221
First Author: He J
Year: 2023
Journal: Sci Adv
Title: Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells.
Volume: 9
Issue: 46
Pages: eadh0322
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
27050272 | J:309012
First Author: Seidel P
Year: 2016
Journal: Oncotarget
Title: Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis.
Volume: 7
Issue: 17
Pages: 23006-18
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Publication
34236050 | J:312900
 
First Author: Sano S
Year: 2021
Journal: JCI Insight
Title: TP53-mediated therapy-related clonal hematopoiesis contributes to doxorubicin-induced cardiomyopathy by augmenting a neutrophil-mediated cytotoxic response.
Volume: 6
Issue: 13
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Publication
19718024 | J:155013
First Author: Ruzankina Y
Year: 2009
Journal: Nat Genet
Title: Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Volume: 41
Issue: 10
Pages: 1144-9
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Publication
35198879 | J:327544
First Author: Peek SL
Year: 2022
Journal: iScience
Title: p53-mediated neurodegeneration in the absence of the nuclear protein Akirin2.
Volume: 25
Issue: 2
Pages: 103814
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Publication
33200984 | J:299451
   
First Author: Atkins A
Year: 2020
Journal: Elife
Title: SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.
Volume: 9
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Publication
27425618 | J:238661
First Author: Sato S
Year: 2016
Journal: Cell Rep
Title: Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype.
Volume: 16
Issue: 4
Pages: 917-927
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Publication
24722541 | J:210515
 
First Author: Munne PM
Year: 2014
Journal: Sci Rep
Title: TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli.
Volume: 4
Pages: 4663
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Publication
30703085 | J:270809
First Author: Thwaites MJ
Year: 2019
Journal: PLoS One
Title: Context dependent roles for RB-E2F transcriptional regulation in tumor suppression.
Volume: 14
Issue: 1
Pages: e0203577
•
•
•
•
•
Publication
28199840 | J:252554
First Author: Bianchi FT
Year: 2017
Journal: Cell Rep
Title: Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly.
Volume: 18
Issue: 7
Pages: 1674-1686
•
•
•
•
•
Publication
29396424 | J:301795
First Author: Zhao Y
Year: 2018
Journal: Cell Death Dis
Title: Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes.
Volume: 9
Issue: 2
Pages: 145
•
•
•
•
•
Publication
34427181 | J:310649
   
First Author: Viais R
Year: 2021
Journal: Elife
Title: Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development.
Volume: 10
•
•
•
•
•
Publication
23873265 | J:318818
 
First Author: Li Y
Year: 2013
Journal: Nat Commun
Title: The p53-PUMA axis suppresses iPSC generation.
Volume: 4
Pages: 2174
•
•
•
•
•
Publication
25144937 | J:223276
 
First Author: Xiong X
Year: 2014
Journal: Elife
Title: Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis.
Volume: 3
Pages: e02236
•
•
•
•
•
Publication
26613412 | J:269486
   
First Author: Gao J
Year: 2015
Journal: Elife
Title: The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis.
Volume: 4
•
•
•
•
•
Publication
23000175 | J:191005
First Author: Kerr JB
Year: 2012
Journal: Mol Cell
Title: DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa.
Volume: 48
Issue: 3
Pages: 343-52
•
•
•
•
•
Publication
24482479 | J:207474
First Author: Bolcun-Filas E
Year: 2014
Journal: Science
Title: Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway.
Volume: 343
Issue: 6170
Pages: 533-6
•
•
•
•
•
Publication
20212136 | J:158687
First Author: Wang Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Cis lethal genetic interactions attenuate and alter p53 tumorigenesis.
Volume: 107
Issue: 12
Pages: 5511-5
•
•
•
•
•
Publication
24013501 | J:201153
First Author: Hamard PJ
Year: 2013
Journal: Genes Dev
Title: The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo.
Volume: 27
Issue: 17
Pages: 1868-85
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
17470788 | J:121586
First Author: Li L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: PACT is a negative regulator of p53 and essential for cell growth and embryonic development.
Volume: 104
Issue: 19
Pages: 7951-6
•
•
•
•
•
Publication
7947386 | J:56433
First Author: Li B
Year: 1994
Journal: Cell Growth Differ
Title: Preferential overexpression of a 172Arg-->Leu mutant p53 in the mammary gland of transgenic mice results in altered lobuloalveolar development.
Volume: 5
Issue: 7
Pages: 711-21
•
•
•
•
•
Publication
28163043 | J:277024
 
First Author: Kannappan R
Year: 2017
Journal: EBioMedicine
Title: p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.
Volume: 16
Pages: 224-237
•
•
•
•
•
Publication
23840687 | J:203714
First Author: Vuong L
Year: 2013
Journal: PLoS One
Title: p53 selectively regulates developmental apoptosis of rod photoreceptors.
Volume: 8
Issue: 6
Pages: e67381
•
•
•
•
•
Publication
30651598 | J:295058
First Author: Gunaratna RT
Year: 2019
Journal: Oncogene
Title: Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model.
Volume: 38
Issue: 18
Pages: 3535-3550
•
•
•
•
•
Publication
28137912 | J:243936
 
First Author: Ma S
Year: 2017
Journal: Mol Cell Biol
Title: L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Volume: 37
Issue: 8
•
•
•
•
•
Publication
32733644 | J:303240
First Author: Xu EY
Year: 2020
Journal: Oncotarget
Title: Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice.
Volume: 11
Issue: 28
Pages: 2718-2739
•
•
•
•
•




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