Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_19 |
|
Specimen Label: |
euxassay_013672_19 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_20 |
|
Specimen Label: |
euxassay_013672_20 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_21 |
|
Specimen Label: |
euxassay_013672_21 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_22 |
|
Specimen Label: |
euxassay_013672_22 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_05 |
|
Specimen Label: |
euxassay_013672_05 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_06 |
|
Specimen Label: |
euxassay_013672_06 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_21 |
|
Specimen Label: |
euxassay_013672_21 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_22 |
|
Specimen Label: |
euxassay_013672_22 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_07 |
|
Specimen Label: |
euxassay_013672_07 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_08 |
|
Specimen Label: |
euxassay_013672_08 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_09 |
|
Specimen Label: |
euxassay_013672_09 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_19 |
|
Specimen Label: |
euxassay_013672_19 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_20 |
|
Specimen Label: |
euxassay_013672_20 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_12 |
|
Specimen Label: |
euxassay_013672_12 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_13 |
|
Specimen Label: |
euxassay_013672_13 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_16 |
|
Specimen Label: |
euxassay_013672_16 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_17 |
|
Specimen Label: |
euxassay_013672_17 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417010 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828945 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013672_18 |
|
Specimen Label: |
euxassay_013672_18 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Robert F |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair. |
Volume: |
26 |
Issue: |
2 |
Pages: |
402-12 |
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Publication |
First Author: |
Xia W |
Year: |
2019 |
Journal: |
Clin Genet |
Title: |
Novel TRRAP mutation causes autosomal dominant non-syndromic hearing loss. |
Volume: |
96 |
Issue: |
4 |
Pages: |
300-308 |
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DO Term |
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Interaction Experiment |
Description: |
The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. |
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Interaction Experiment |
Description: |
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. |
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Publication |
First Author: |
McMahon SB |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. |
Volume: |
20 |
Issue: |
2 |
Pages: |
556-62 |
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Publication |
First Author: |
McMahon SB |
Year: |
1998 |
Journal: |
Cell |
Title: |
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. |
Volume: |
94 |
Issue: |
3 |
Pages: |
363-74 |
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Protein Domain |
Type: |
Repeat |
Description: |
This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) [].This entry represents part of the Tra1 protein composed of α-solenoid repeats that form a ring region []. |
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Protein Domain |
Type: |
Family |
Description: |
This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) []. |
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HT Experiment |
Series Id: |
GSE43650 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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Publication |
First Author: |
Sharov G |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1556 |
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Protein Domain |
Type: |
Repeat |
Description: |
This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) [].This entry represents part of the Tra1 protein composed of α-solenoid repeats that forms the central region []. This is named as central due to its position relative to the ring region. |
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Publication |
First Author: |
Brown CE |
Year: |
2001 |
Journal: |
Science |
Title: |
Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit. |
Volume: |
292 |
Issue: |
5525 |
Pages: |
2333-7 |
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Publication |
First Author: |
Grant PA |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
The ATM-related cofactor Tra1 is a component of the purified SAGA complex. |
Volume: |
2 |
Issue: |
6 |
Pages: |
863-7 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
267
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3859
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3858
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3829
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3587
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3847
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2565
 |
Fragment?: |
false |
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Protein Domain |
Type: |
Family |
Description: |
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65kDa subunit 5L (TAF5L) is a component of the a component of the PCAF complex, the human version of the yeast SAGA complex []. TAF5L is also a component of the STAGA transcription coactivator-HAT complex [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].The STAGA transcription coactivator-HAT complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors. The STAGA complex is composed of at least SUPT3H, KAT2A, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9 []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2724
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
374
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
192
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
589
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
560
 |
Fragment?: |
true |
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Publication |
First Author: |
Pray-Grant MG |
Year: |
2005 |
Journal: |
Nature |
Title: |
Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation. |
Volume: |
433 |
Issue: |
7024 |
Pages: |
434-8 |
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Publication |
First Author: |
Han Y |
Year: |
2014 |
Journal: |
EMBO J |
Title: |
Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex. |
Volume: |
33 |
Issue: |
21 |
Pages: |
2534-46 |
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