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Search results 101 to 200 out of 729 for Ttk

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Hits by Strain

Type Details Score
Gene
398219 | ttk.S
Type: gene
Organism: frog, African clawed
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Protein
Q6PD96
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 94
Description: Phosphothreonine; by TTK
Type: modified residue
End: 94
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Allele
Ttk<tm1Smoc> | MGI:7293033
Name: Ttk protein kinase; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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UniProt Feature
UniProt Feature
Begin: 1
Description: Dual specificity protein kinase TTK
Type: chain
End: 856
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Protein
A0A087WPS8
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
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Protein
Q3TPW2
Organism: Mus musculus/domesticus
Length: 773  
Fragment?: false
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Strain
MGI:6354335 | B6;129-Ttk<tm1Smoc>/Smoc
Attribute String: mutant strain, targeted mutation
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Protein
P35761
Organism: Mus musculus/domesticus
Length: 856  
Fragment?: false
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Protein
P35761-2
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
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Allele
Ttk<+> | MGI:2435021
   
Name: Ttk protein kinase; wild type
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Allele
Ttk<Gt(YTA024)Byg> | MGI:3880670
 
Name: Ttk protein kinase; gene trap YTA024, BayGenomics
Allele Type: Gene trapped
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Allele
Ttk<em1(IMPC)J> | MGI:6367822
Name: Ttk protein kinase; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Ttk<Gt(A023E04)Wrst> | MGI:4122654
 
Name: Ttk protein kinase; gene trap A023E04, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Ttk<Gt(OST114871)Lex> | MGI:4189687
 
Name: Ttk protein kinase; gene trap OST114871, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Ttk<Gt(OST147691)Lex> | MGI:4205090
 
Name: Ttk protein kinase; gene trap OST147691, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Ttk<Gt(OST194061)Lex> | MGI:4225410
 
Name: Ttk protein kinase; gene trap OST194061, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Ttk<Gt(OST196894)Lex> | MGI:4226917
 
Name: Ttk protein kinase; gene trap OST196894, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Ttk<Gt(OST220006)Lex> | MGI:4238301
 
Name: Ttk protein kinase; gene trap OST220006, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Ttk<Gt(G042B10)Wrst> | MGI:4334784
 
Name: Ttk protein kinase; gene trap G042B10, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Ttk<Gt(P019C03)Wrst> | MGI:4340212
 
Name: Ttk protein kinase; gene trap P019C03, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Ttk<Gt(AR0284)Wtsi> | MGI:4346547
 
Name: Ttk protein kinase; gene trap AR0284, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Ttk<Gt(AT0190)Wtsi> | MGI:4346793
 
Name: Ttk protein kinase; gene trap AT0190, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Ttk<Gt(EUCE0168a08)Hmgu> | MGI:4386941
 
Name: Ttk protein kinase; gene trap EUCE0168a08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Ttk<tm1a(EUCOMM)Hmgu> | MGI:4941539
Name: Ttk protein kinase; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Ttk<tm1Katj> | MGI:5056148
Name: Ttk protein kinase; targeted mutation 1, Katja Wassmann
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6367823 | C57BL/6NJ-Ttk<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Ttk<tm1.1Kops> | MGI:6404032
Name: Ttk protein kinase; targeted mutation 1.1, Geert Kops
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
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Allele
Ttk<tm2.1Kops> | MGI:6404036
Name: Ttk protein kinase; targeted mutation 2.1, Geert Kops
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
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Allele
Ttk<em11Gpt> | MGI:7308084
Name: Ttk protein kinase; endonuclease-mediated mutation 11, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Ttk<em1Gpt> | MGI:7308085
Name: Ttk protein kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Ttk/Ttk
Background: C57BL/6NJ-Ttk/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6440103 | B6;129S5-Ttk<Gt(OST220006)Lex>/Tac
Attribute String: mutant stock, gene trap
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Allele
Ttk<Gt(435F6)Cmhd> | MGI:4962059
 
Name: Ttk protein kinase; gene trap 435F6, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Ttk<Gt(80B8)Cmhd> | MGI:4973078
 
Name: Ttk protein kinase; gene trap 80B8, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Ttk<Gt(IST14387E12)Tigm> | MGI:5229207
 
Name: Ttk protein kinase; gene trap IST14387E12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Ttk<Gt(IST14419E4)Tigm> | MGI:5235479
 
Name: Ttk protein kinase; gene trap IST14419E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:6404033 | B6.129P2(SJL)-Ttk<tm1.1Kops>/JlmaJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6404039 | B6.129P2(SJL)-Ttk<tm2.1Kops>/JlmaJ
Attribute String: targeted mutation, mutant strain, congenic
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Protein Coding Gene
MGI:2155779 | Ttbk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Zp3-cre)93Knw/? Ttk/Ttk
Background: involves: 129 * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ttk/Ttk<+>
Background: C57BL/6NJ-Ttk/Mmjax
Zygosity: ht
Has Mutant Allele: true
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GO Term
GO:0050321 | tau-protein kinase activity
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GO Term
GO:1902947 | regulation of tau-protein kinase activity
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Publication
11257498 | J:68153
First Author: Tomizawa K
Year: 2001
Journal: FEBS Lett
Title: Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau.
Volume: 492
Issue: 3
Pages: 221-7
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Publication
20231359 | J:242469
First Author: Iida R
Year: 2010
Journal: Mol Cell Biol
Title: A novel transcriptional repressor, Rhit, is involved in heat-inducible and age-dependent expression of Mpv17-like protein, a participant in reactive oxygen species metabolism.
Volume: 30
Issue: 10
Pages: 2306-15
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Protein Domain
IPR024182 | Vaccinia_A55R
Type: Family
Description: This family includes ORF A55R from Vaccinia virus, which is characterised by having a BTB (for BR-C, ttk and bab) []or POZ (for Pox virus and Zinc finger) []domain near the N terminus. The proteins are also characterised by kelch repeats C-terminal to the BTB domain. The function of these proteins are unknown.
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GO Term
GO:1902948 | negative regulation of tau-protein kinase activity
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Publication
7958847 | -
First Author: Bardwell VJ
Year: 1994
Journal: Genes Dev
Title: The POZ domain: a conserved protein-protein interaction motif.
Volume: 8
Issue: 14
Pages: 1664-77
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Publication
7938017 | -
First Author: Zollman S
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.
Volume: 91
Issue: 22
Pages: 10717-21
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Protein
E9Q173
Organism: Mus musculus/domesticus
Length: 522  
Fragment?: false
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Protein
F7C1U0
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: true
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Protein
D3YZI8
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Protein
E0CXJ5
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
A0A140LIJ9
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: false
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Protein
A0A3B2W7K3
Organism: Mus musculus/domesticus
Length: 274  
Fragment?: false
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Protein
E9Q945
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
A0A140LIH9
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
E0CZ94
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Protein
A0A338P7A5
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
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Protein
B7ZMY3
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Publication
9019154 | -
First Author: Deweindt C
Year: 1995
Journal: Cell Growth Differ
Title: The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain.
Volume: 6
Issue: 12
Pages: 1495-503
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Publication
9765306 | -
First Author: Wong CW
Year: 1998
Journal: J Biol Chem
Title: Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.
Volume: 273
Issue: 42
Pages: 27695-702
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Publication
9824158 | -
First Author: Huynh KD
Year: 1998
Journal: Oncogene
Title: The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT.
Volume: 17
Issue: 19
Pages: 2473-84
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Publication
17384421 | -
First Author: Costoya JA
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: Functional analysis of the role of POK transcriptional repressors.
Volume: 6
Issue: 1
Pages: 8-18
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Publication
9917379 | J:52555
First Author: Aravind L
Year: 1999
Journal: J Mol Biol
Title: Fold prediction and evolutionary analysis of the POZ domain: structural and evolutionary relationship with the potassium channel tetramerization domain.
Volume: 285
Issue: 4
Pages: 1353-61
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Protein Domain
IPR011333 | SKP1/BTB/POZ_sf
Type: Homologous_superfamily
Description: The BTB (for BR-C, ttk and bab) []or POZ (for Pox virus and Zinc finger) [, ]domain is a versatile protein-protein interaction motif involved in many cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination []. The BTB domain can occur alongside other domains: BTB-zinc finger (BTB-ZF), BTB-BACK-Kelch (BBK), voltage-gated potassium channel T1 (T1-Kv) [], MATH-BTB, BTB-NPH3 and BTB-BACK-PHR (BBP). Other proteins, such as Skp1 and ElonginC, consist almost exclusively of the core BTB fold. In all of these protein families, the BTB core fold is structurally conserved, consisting of a 2-layer alpha/beta topology where a cluster of alpha helices is flanked by short β-sheets []. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [, , ]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.This entry includes the BTB/POZ domain, as well as Skp1 N-terminal region which has an α/β structure similar to that of the BTB/POZ domain fold [, ].
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Protein
A0A0A6YY25
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: false
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Protein
Q562E2
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
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Protein
G3UY12
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Protein
Q8BI95
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
A2ASL5
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Protein
H3BKN3
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
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Protein
Z4YN22
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
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Protein
Q5F295
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Protein
Q8K438
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
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Protein
Q3TSF4
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
A2CF73
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
G3UWM3
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
A0A1B0GRT4
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
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Protein
F6XZI3
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
Q9CSZ1
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Protein
A0A571BER1
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: true
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Protein
G3UYC4
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: false
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Protein
A0A0A6YWR6
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
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Protein
A0A286YDW0
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
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Protein
D6RGL5
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Protein
E9PVN1
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
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Protein
A0A0A6YWT8
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: true
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Protein
Q8BV39
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Protein
D3Z7J5
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
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Protein
F7ALN1
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
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Protein
E0CZ26
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
D3Z0B5
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
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Protein
H3BKL0
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
Q8CBQ4
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
E0CXK1
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
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Protein
D3Z1Y7
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
A2ARL3
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
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Protein
F6TGP8
Organism: Mus musculus/domesticus
Length: 50  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom