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Search results 101 to 188 out of 188 for Ube2b

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0.023s
Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312040
Specimen Label: MRC Harwell_1312040
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312048
Specimen Label: MRC Harwell_1312048
Detected: true
Specimen Num: 28
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312046
Specimen Label: MRC Harwell_1312046
Detected: true
Specimen Num: 26
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312048
Specimen Label: MRC Harwell_1312048
Detected: true
Specimen Num: 28
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312051
Specimen Label: MRC Harwell_1312051
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312050
Specimen Label: MRC Harwell_1312050
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312053
Specimen Label: MRC Harwell_1312053
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312057
Specimen Label: MRC Harwell_1312057
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690951
Age: postnatal adult
Image: MRC Harwell_1312051
Specimen Label: MRC Harwell_1312051
Detected: true
Specimen Num: 3
Publication
First Author: Cooke HJ
Year: 2002
Journal: Nat Rev Genet
Title: Mouse models of male infertility.
Volume: 3
Issue: 10
Pages: 790-801
Publication
First Author: Liebe B
Year: 2006
Journal: Exp Cell Res
Title: Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.
Volume: 312
Issue: 19
Pages: 3768-81
Publication
First Author: Wefes I
Year: 1995
Journal: Gene
Title: Characterization of a cDNA clone encoding E2-20K, a murine ubiquitin-conjugating enzyme.
Volume: 163
Issue: 2
Pages: 321-2
Publication
First Author: Ma Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Loss of RAD6B induces degeneration of the cochlea in mice.
Volume: 531
Issue: 3
Pages: 402-408
Publication  
First Author: Ye Q
Year: 2022
Journal: Neuroscience
Title: The Role of RAD6B and PEDF in Retinal Degeneration.
Volume: 480
Pages: 19-31
Publication
First Author: Chau V
Year: 1989
Journal: Science
Title: A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein.
Volume: 243
Issue: 4898
Pages: 1576-83
Publication
First Author: Koken MH
Year: 1992
Journal: Genomics
Title: Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.
Volume: 12
Issue: 3
Pages: 447-53
Publication
First Author: Notenboom V
Year: 2007
Journal: Nucleic Acids Res
Title: Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification.
Volume: 35
Issue: 17
Pages: 5819-30
Publication
First Author: Grigoryev S
Year: 1996
Journal: J Biol Chem
Title: A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway.
Volume: 271
Issue: 45
Pages: 28521-32
Publication
First Author: Tateishi S
Year: 2003
Journal: Mol Cell Biol
Title: Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells.
Volume: 23
Issue: 2
Pages: 474-81
Publication
First Author: Kwon YT
Year: 2003
Journal: Mol Cell Biol
Title: Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.
Volume: 23
Issue: 22
Pages: 8255-71
Publication
First Author: Tasaki T
Year: 2007
Journal: J Biol Chem
Title: Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.
Volume: 282
Issue: 25
Pages: 18510-20
Publication
First Author: Rout UK
Year: 1997
Journal: Cell Calcium
Title: Ethanol-induced intracellular calcium mobilization rapidly alters gene expression in the mouse blastocyst.
Volume: 22
Issue: 6
Pages: 463-74
Publication
First Author: Grootegoed JA
Year: 1998
Journal: Mol Cell Endocrinol
Title: Knockout mouse model and gametogenic failure.
Volume: 145
Issue: 1-2
Pages: 161-6
Publication
First Author: Kwon YT
Year: 2000
Journal: Mol Cell Biol
Title: Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.
Volume: 20
Issue: 11
Pages: 4135-48
Publication
First Author: Baarends WM
Year: 2005
Journal: Mol Cell Biol
Title: Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.
Volume: 25
Issue: 3
Pages: 1041-53
Publication
First Author: van der Laan R
Year: 2004
Journal: J Cell Sci
Title: Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.
Volume: 117
Issue: Pt 21
Pages: 5023-33
Publication
First Author: Roller ML
Year: 1995
Journal: Mamm Genome
Title: Localization of sequences related to the human RAD6 DNA repair gene on mouse chromosomes 11 and 13.
Volume: 6
Issue: 4
Pages: 305-6
Publication
First Author: Zhou J
Year: 2017
Journal: Biochim Biophys Acta
Title: Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.
Volume: 1860
Issue: 12
Pages: 1159-1168
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
Publication
First Author: Unk I
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.
Volume: 103
Issue: 48
Pages: 18107-12
Publication
First Author: Xiao W
Year: 2000
Journal: Genetics
Title: The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways.
Volume: 155
Issue: 4
Pages: 1633-41
Publication
First Author: Parker JL
Year: 2012
Journal: Nucleic Acids Res
Title: A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA.
Volume: 40
Issue: 22
Pages: 11380-8
Protein Domain
Type: Family
Description: This entry includes Rad18 from eukaryotes. Rad18 is a E3 ubiquitin ligase required for postreplication repair []. In budding yeast, Rad18 forms a heterodimer with Rad6 to monoubiquitinate PCNA at a highly conserved lysine, 'Lys-164' []. In humans, Rad18 associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164' [].
Allele
Name: ubiquitin-conjugating enzyme E2B; targeted mutation 1, Jan H J Hoeijmakers
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Ube2b/Ube2b
Background: involves: 129P2/OlaHsd * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ube2b/Ube2b
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ube2b/Ube2b
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ube2b/Ube2b
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ube2b/Ube2b
Background: FVB.129P2-Ube2b
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ube2a/? Ube2b/Ube2b
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ube2a/? Ube2b/Ube2b<+>
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ube2a/Ube2a Ube2b/Ube2b
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ube2a/Ube2a<+> Ube2b/Ube2b
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ube2a/Ube2a Ube2b/Ube2b<+>
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Robson A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility.
Volume: 116
Issue: 28
Pages: 14049-14054
Publication
First Author: Howard M
Year: 2016
Journal: In Vitro Cell Dev Biol Anim
Title: The function and interrelationship between GDF5 and ERG-010 during chondrogenesis in vitro.
Volume: 52
Issue: 2
Pages: 182-92
Protein
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 496  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 556  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 556  
Fragment?: false