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Search results 101 to 200 out of 201 for Ube2i

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Type Details Score
Publication
8839844 | J:35784
First Author: Scott LM
Year: 1996
Journal: Blood
Title: E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha.
Volume: 88
Issue: 7
Pages: 2517-30
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Publication
15173587 | J:91045
First Author: Collavin L
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Modification of the erythroid transcription factor GATA-1 by SUMO-1.
Volume: 101
Issue: 24
Pages: 8870-5
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Publication
18681895 | J:142156
First Author: Kuwata T
Year: 2008
Journal: Genes Cells
Title: BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body.
Volume: 13
Issue: 9
Pages: 931-40
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Publication
17097055 | J:116485
First Author: Tsuruzoe S
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Inhibition of DNA binding of Sox2 by the SUMO conjugation.
Volume: 351
Issue: 4
Pages: 920-6
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Publication
9223278 | J:41993
First Author: Tashiro K
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha.
Volume: 94
Issue: 15
Pages: 7862-7
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Publication
22303332 | J:185874
 
First Author: Field MS
Year: 2011
Journal: Front Genet
Title: Mthfs is an Essential Gene in Mice and a Component of the Purinosome.
Volume: 2
Pages: 36
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Publication
30375383 | J:268526
First Author: Singh AK
Year: 2018
Journal: Nat Commun
Title: SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2.
Volume: 9
Issue: 1
Pages: 4515
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Publication
25448527 | J:272282
 
First Author: Lee L
Year: 2014
Journal: Sci Rep
Title: Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.
Volume: 4
Pages: 7190
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Publication
32948837 | J:299456
First Author: López I
Year: 2020
Journal: Oncogene
Title: An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.
Volume: 39
Issue: 43
Pages: 6692-6703
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Publication
16421255 | J:112468
First Author: Tiefenbach J
Year: 2006
Journal: Mol Biol Cell
Title: SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.
Volume: 17
Issue: 4
Pages: 1643-51
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Publication
31749687 | J:346418
 
First Author: Colnaghi L
Year: 2019
Journal: Front Cell Neurosci
Title: Super Resolution Microscopy of SUMO Proteins in Neurons.
Volume: 13
Pages: 486
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Publication
16908015 | J:112883
First Author: Yamaguchi YL
Year: 2006
Journal: Dev Biol
Title: Stage-specific Importin13 activity influences meiosis of germ cells in the mouse.
Volume: 297
Issue: 2
Pages: 350-60
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Publication
22366399 | J:183253
First Author: Yukita A
Year: 2012
Journal: Bone
Title: Ubc9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells.
Volume: 50
Issue: 5
Pages: 1092-9
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Publication
12200424 | J:80041
First Author: Heng JI
Year: 2002
Journal: J Biol Chem
Title: Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.
Volume: 277
Issue: 45
Pages: 43152-9
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Publication
18955028 | J:144079
First Author: Kim EJ
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1.
Volume: 377
Issue: 3
Pages: 952-6
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Publication
21563299 | J:325290
First Author: Wang J
Year: 2011
Journal: Birth Defects Res A Clin Mol Teratol
Title: Defective sumoylation pathway directs congenital heart disease.
Volume: 91
Issue: 6
Pages: 468-76
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Publication
34110283 | J:326734
   
First Author: He Y
Year: 2021
Journal: Elife
Title: T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.
Volume: 10
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Publication
22207709 | J:192701
First Author: Bloch M
Year: 2012
Journal: Circ Res
Title: High-mobility group A1 protein: a new coregulator of peroxisome proliferator-activated receptor-γ-mediated transrepression in the vasculature.
Volume: 110
Issue: 3
Pages: 394-405
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Publication
15569683 | J:96947
First Author: Takahashi H
Year: 2005
Journal: J Biol Chem
Title: Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein.
Volume: 280
Issue: 7
Pages: 5611-21
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Publication
21183956 | J:186966
First Author: Jiang M
Year: 2011
Journal: Cell Death Differ
Title: SUMO-specific protease 2 in Mdm2-mediated regulation of p53.
Volume: 18
Issue: 6
Pages: 1005-15
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Publication
16940173 | J:114656
First Author: Quinlan KG
Year: 2006
Journal: Mol Cell Biol
Title: Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression.
Volume: 26
Issue: 21
Pages: 8202-13
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Protein
Q8CFZ0
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
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Publication
17187077 | J:245382
First Author: Park SW
Year: 2007
Journal: Nat Struct Mol Biol
Title: SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells.
Volume: 14
Issue: 1
Pages: 68-75
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Publication
36427672 | J:345334
 
First Author: Xie H
Year: 2023
Journal: Metabolism
Title: SUMOylation of ERp44 enhances Ero1α ER retention contributing to the pathogenesis of obesity and insulin resistance.
Volume: 139
Pages: 155351
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Publication
16127449 | J:101497
First Author: Pascual G
Year: 2005
Journal: Nature
Title: A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.
Volume: 437
Issue: 7059
Pages: 759-63
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Publication
24639124 | J:215364
First Author: Hasegawa Y
Year: 2014
Journal: J Comp Neurol
Title: Spatiotemporal distribution of SUMOylation components during mouse brain development.
Volume: 522
Issue: 13
Pages: 3020-36
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Publication
15767674 | J:97581
First Author: Gómez-del Arco P
Year: 2005
Journal: Mol Cell Biol
Title: Ikaros SUMOylation: switching out of repression.
Volume: 25
Issue: 7
Pages: 2688-97
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Publication
34267330 | J:309380
First Author: Mei L
Year: 2021
Journal: Oncogene
Title: SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.
Volume: 40
Issue: 35
Pages: 5357-5366
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Publication
15237213 | J:91422
First Author: Evsikov AV
Year: 2004
Journal: Cytogenet Genome Res
Title: Systems biology of the 2-cell mouse embryo.
Volume: 105
Issue: 2-4
Pages: 240-50
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Publication
29592913 | J:355796
 
First Author: Lu X
Year: 2018
Journal: Biol Open
Title: Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis.
Volume: 7
Issue: 3
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 564
Description: Hydrophobic interaction with UBE2I
Type: site
End: 564
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UniProt Feature
UniProt Feature
Begin: 567
Description: Hydrophobic interaction with UBE2I
Type: site
End: 567
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HT Experiment
GSE218484 | The E2 SUMO-conjugating enzyme UBE2I is essential for chromatin dynamics and transcriptional silencing in mouse oocytes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(UBE2I-cre)1Xxh | MGI:3663673
Name: transgene insertion 1, Xianxin Hua
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
28270438 | J:247077
First Author: Muhammad AB
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.
Volume: 313
Issue: 2
Pages: E148-E166
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Publication
16740708 | J:110111
First Author: Schnepp RW
Year: 2006
Journal: Cancer Res
Title: Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells.
Volume: 66
Issue: 11
Pages: 5707-15
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GO Term
GO:1990354 | activated SUMO-E1 ligase complex
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Publication
20159607 | J:157685
First Author: Thiel AT
Year: 2010
Journal: Cancer Cell
Title: MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
Volume: 17
Issue: 2
Pages: 148-59
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Publication
30902831 | J:277113
First Author: Gui J
Year: 2019
Journal: Mol Cancer Res
Title: The PKR-Like Endoplasmic Reticulum Kinase Promotes the Dissemination of Myc-Induced Leukemic Cells.
Volume: 17
Issue: 7
Pages: 1450-1458
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Publication
26627716 | J:228322
First Author: Yu Q
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Type I interferons mediate pancreatic toxicities of PERK inhibition.
Volume: 112
Issue: 50
Pages: 15420-5
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Publication
14500712 | -
First Author: Kadaré G
Year: 2003
Journal: J Biol Chem
Title: PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation.
Volume: 278
Issue: 48
Pages: 47434-40
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Protein Domain
IPR027227 | PIAS1
Type: Family
Description: PIAS1 is an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and acts as a SUMO-tethering factor []. SUMO proteins are ubiquitin like proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMO is first activated in an ATP-dependent reaction by formation of a thioester bond with an E1 (SUMO-activating) enzyme and then transferred to the SUMO conjugating (E2) enzyme Ubc9. Ubc9 catalyses the formation of an isopeptide bond between the C-terminal of SUMO and the amino group of lysine in the target protein. Sumoylated proteins can be targeted for different cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability [].
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Publication
9388184 | J:52872
First Author: Chung CD
Year: 1997
Journal: Science
Title: Specific inhibition of Stat3 signal transduction by PIAS3.
Volume: 278
Issue: 5344
Pages: 1803-5
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Publication
11060035 | J:175118
First Author: Rödel B
Year: 2000
Journal: EMBO J
Title: The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3.
Volume: 19
Issue: 21
Pages: 5845-55
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Publication
11709556 | -
First Author: Levy C
Year: 2002
Journal: J Biol Chem
Title: A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor.
Volume: 277
Issue: 3
Pages: 1962-6
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Protein
Q3TM95
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
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Publication
25406032 | -
 
First Author: Park JH
Year: 2014
Journal: Nat Commun
Title: Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage.
Volume: 5
Pages: 5483
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Publication
24651376 | -
First Author: Sun X
Year: 2014
Journal: PLoS One
Title: Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells.
Volume: 9
Issue: 3
Pages: e92746
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Protein Domain
IPR027226 | PIAS3
Type: Family
Description: PIAS3 is an E3-type small ubiquitin-like modifier (SUMO) ligases, stabilising the interaction between UBE2I and Ubc9 respectively and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway [, , , ].PIAS3 sumoylates CCAR2, promoting its interaction with SIRT1 []and diminishes the sumoylation of ZFHX3 by preventing the colocalization of ZFHX3 with SUMO1 in the nucleus [].SUMO proteins are ubiquitin like proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMO is first activated in an ATP-dependent reaction by formation of a thioester bond with an E1 (SUMO-activating) enzyme and then transferred to the SUMO conjugating (E2) enzyme Ubc9. Ubc9 catalyses the formation of an isopeptide bond between the C-terminal of SUMO and the amino group of lysine in the target protein. Sumoylated proteins can be targeted for different cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability [].
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Publication
14596924 | J:86405
First Author: Duval D
Year: 2003
Journal: FEBS Lett
Title: The 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L.
Volume: 554
Issue: 1-2
Pages: 111-8
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Publication
12383504 | J:79579
First Author: Su HL
Year: 2002
Journal: Gene
Title: Molecular features of human ubiquitin-like SUMO genes and their encoded proteins.
Volume: 296
Issue: 1-2
Pages: 65-73
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Protein
H3BJ41
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: false
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Protein
E0CZH5
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Protein
Q3UYT2
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: true
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Protein
A0A1L1SRS2
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: true
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Protein
O88907
Organism: Mus musculus/domesticus
Length: 651  
Fragment?: false
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Protein
O54714
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: false
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Protein
Q3U556
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: false
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Protein
E0CZ31
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q2M4G9
Organism: Mus musculus/domesticus
Length: 651  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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