| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3283722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842522 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
| Note: |
Expression was strong in the endocrine system. |
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1781522 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1759722 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1775122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691857 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_1467914 |
|
| Specimen Label: |
MRC Harwell_1467914 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274122 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287422 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266022 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1624622 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
| Note: |
Expression was detected in the digestive system. |
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1721422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1646922 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736222 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1683322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1700022 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1832122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876522 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
| Note: |
Expression was detected in the immune system. |
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1741222 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3599822 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280922 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1833322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752522 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1821522 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3557722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668822 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757522 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1802422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1768022 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression was not detected in the skull (base and vault). |
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309595 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2672022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5422961 |
| Age: |
embryonic day 14.5 |
| Image: |
ST73; Specimen C1639 |
| Note: |
Expression was weak in whisker follicle. |
| Specimen Label: |
ST73; Specimen C1639 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
5180
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
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Mouse Genome Informatics Scientific Curators |
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International Knockout Mouse Consortium |
| Year: |
2014 |
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MGI download of modified allele data from IKMC and creation of new knockout alleles |
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International Mouse Strain Resource |
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2014 |
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Database Download |
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MGI download of germline transmission data for alleles from IMSR strain data |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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2014 |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
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| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Mouse Genome Informatics Scientific Curators |
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MGI Sequence Curation Reference |
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Kawai J |
| Year: |
2001 |
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Nature |
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Functional annotation of a full-length mouse cDNA collection. |
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| Issue: |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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GemPharmatech |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
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AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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UniProt-GOA |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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The Gene Ontology Consortium |
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Diez-Roux G |
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PLoS Biol |
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Mouse Genome Informatics Scientific Curators |
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Mouse Genome Informatics Computational Sequence to Gene Associations |
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Mouse Genome Informatics Scientific Curators |
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MGI-UniGene Interconnection Effort |
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Annotation inferences using phylogenetic trees |
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Mouse Genome Database and National Center for Biotechnology Information |
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Allen Institute for Brain Science |
| Year: |
2004 |
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Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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Mouse Genome Informatics Group |
| Year: |
2003 |
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Database Procedure |
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Automatic Encodes (AutoE) Reference |
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| First Author: |
Bairoch A |
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1999 |
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Database Release |
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SWISS-PROT Annotated protein sequence database |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
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|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
469
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2021
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
5208
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
5156
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
E3 ubiquitin-protein ligase UBR4 |
| Type: |
chain |
| End: |
5180 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2065
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
204
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1301
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hong JH |
| Year: |
2015 |
| Journal: |
Mol Cell Proteomics |
| Title: |
KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation. |
| Volume: |
14 |
| Issue: |
3 |
| Pages: |
674-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morrison J |
| Year: |
2013 |
| Journal: |
PLoS Pathog |
| Title: |
Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling. |
| Volume: |
9 |
| Issue: |
3 |
| Pages: |
e1003265 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ashton-Beaucage D |
| Year: |
2016 |
| Journal: |
PLoS Biol |
| Title: |
The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
e1002539 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the N-terminal domain of E3 ubiquitin-protein ligases UBR4 (POE or PUSHOVER in Drosophila) from animals. UBR4 is a component of the N-rule pathway, identified as noncanonical N-recognins implicated in bulk lysosomal degradation and autophagy. Proteins containing this domain are extraordinarily large proteins that recognise and bind to proteins with N-terminal destabilising residues according to the N-end rule leading them to their ubiquitination and degradation. These proteins share a UBR box with others E3-ligases UBR box proteins, but UBR4 lacks the ubiquitylation domain, suggesting that it may interact with other catalytic proteins [, , ]. |
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•
•
•
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