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Search results 101 to 178 out of 178 for Usp7

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Type Details Score
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
35947662 | J:343847
First Author: Zhang XW
Year: 2022
Journal: Sci Adv
Title: Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy.
Volume: 8
Issue: 32
Pages: eabo0789
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Publication
32820040 | J:303705
First Author: Grunblatt E
Year: 2020
Journal: Genes Dev
Title: MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Volume: 34
Issue: 17-18
Pages: 1210-1226
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Publication
18410486 | J:262357
First Author: Nathan JA
Year: 2008
Journal: Traffic
Title: The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X.
Volume: 9
Issue: 7
Pages: 1130-45
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Publication
30024656 | J:269015
First Author: Yao Y
Year: 2018
Journal: J Leukoc Biol
Title: Blockade of deubiquitinase USP7 overcomes bortezomib resistance by suppressing NF-κB signaling pathway in multiple myeloma.
Volume: 104
Issue: 6
Pages: 1105-1115
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Publication
29416040 | J:257935
First Author: Biswas K
Year: 2018
Journal: Nat Commun
Title: BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage.
Volume: 9
Issue: 1
Pages: 537
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Publication
36152057 | J:330038
First Author: Shao Y
Year: 2022
Journal: Aging (Albany NY)
Title: Ubiquitin-like protein FAT10 promotes renal fibrosis by stabilizing USP7 to prolong CHK1-mediated G2/M arrest in renal tubular epithelial cells.
Volume: 14
Issue: 18
Pages: 7527-7546
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Publication
22466611 | -
First Author: Schwertman P
Year: 2012
Journal: Nat Genet
Title: UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair.
Volume: 44
Issue: 5
Pages: 598-602
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Publication
22411829 | J:182217
First Author: Ma H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.
Volume: 109
Issue: 13
Pages: 4828-33
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GXD Expression
GXD Expression
Probe: MGI:6382565
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-09
Strength: Present
Sex: Female
Emaps: EMAPS:3647427
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7628312
Age: postnatal day 0
Image: S15B Control
Note: Co-localization of expression with Usp7 in granulosa cells
Specimen Label: S15B Control
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:6382565
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-09
Strength: Present
Sex: Female
Emaps: EMAPS:3647428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7628312
Age: postnatal day 7
Image: S15C Control
Note: Co-localization of expression with Usp7 in granulosa cells
Specimen Label: S15C Control
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:6382565
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-09
Strength: Present
Sex: Female
Emaps: EMAPS:3124727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7628312
Age: postnatal day 0
Image: S15B Sf1:Cretg/+;Usp7fl/fl
Note: Co-localization of expression with Usp7 in granulosa cells
Specimen Label: S15B Sf1:Cretg/+;Usp7fl/fl
Detected: true
Specimen Num: 18
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Interaction Experiment
Meng H (2014)
Description: MBD4 Interacts with and Recruits USP7 to heterochromatic foci.
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Publication
25358258 | -
First Author: Meng H
Year: 2015
Journal: J Cell Biochem
Title: MBD4 interacts with and recruits USP7 to heterochromatic foci.
Volume: 116
Issue: 3
Pages: 476-85
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GXD Expression
GXD Expression
Probe: MGI:6382565
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-09
Strength: Present
Sex: Female
Emaps: EMAPS:3124728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7628312
Age: postnatal day 7
Image: S15C Sf1:Cretg/+;Usp7fl/fl
Note: Co-localization of expression with Usp7 in granulosa cells arrested in primordial follicular stage.
Specimen Label: S15C Sf1:Cretg/+;Usp7fl/fl
Detected: true
Specimen Num: 20
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Interaction Experiment
Novellasdemunt L (2017)
Description: USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating -Catenin Deubiquitination.
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Interaction Experiment
Dong X (2021)
Description: USP7 regulates the proliferation and differentiation of ATDC5 cells through the Sox9-PTHrP-PTH1R axis.
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Interaction Experiment
Liu C (2023)
Description: USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.
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Allele
Usp7<em1Smoc> | MGI:7290965
Name: ubiquitin specific peptidase 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
23973222 | -
First Author: van Loosdregt J
Year: 2013
Journal: Immunity
Title: Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
Volume: 39
Issue: 2
Pages: 259-71
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Publication
29045831 | -
First Author: Novellasdemunt L
Year: 2017
Journal: Cell Rep
Title: USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.
Volume: 21
Issue: 3
Pages: 612-627
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Strain
MGI:7623530 | C57BL/6JSmoc-Usp7<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR040172 | ATXN1
Type: Family
Description: Ataxin-1 (ATXN1) is involved in the formation and regulation of multimeric protein complexes within the nucleus []. It is the causative factor for spinocerebellar ataxia type 1 (SCA1), which manifests in poor co-ordination of hand and feet movement []. ATXN1 is a transcription repressor in the Notch signalling pathway []and colocalizes with the deubiquitinating enzyme USP7 in the nucleus [].
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Protein Domain
IPR018610 | UVSSA
Type: Family
Description: UVSSA is part of a UV-induced ubiquitinated protein complex involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. It stabilise the TC-NER master organizing protein ERCC6 (also known as CSB) by delivering the deubiquitinating enzyme USP7 to TC-NER complexes [].
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Publication
7647801 | -
First Author: Servadio A
Year: 1995
Journal: Nat Genet
Title: Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals.
Volume: 10
Issue: 1
Pages: 94-8
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Publication
11001934 | -
First Author: Davidson JD
Year: 2000
Journal: Hum Mol Genet
Title: Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.
Volume: 9
Issue: 15
Pages: 2305-12
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Publication
21475249 | -
First Author: Tong X
Year: 2011
Journal: EMBO Rep
Title: Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.
Volume: 12
Issue: 5
Pages: 428-35
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Protein Domain
IPR043404 | ATAXIN1-like
Type: Family
Description: This entry includes Ataxin1 and Ataxin1-like proteins. They are components of the Notch signalling pathway involved in transcriptional repression [].Ataxin-1 (ATXN1) is involved in the formation and regulation of multimeric protein complexes within the nucleus []. It is the causative factor for spinocerebellar ataxia type 1 (SCA1), which manifests in poor co-ordination of hand and feet movement []. ATXN1 is a transcription repressor in the Notch signalling pathway []and colocalizes with the deubiquitinating enzyme USP7 in the nucleus [].
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HT Experiment
E-MTAB-4989 | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
27863225 | J:238488
First Author: Beringer M
Year: 2016
Journal: Mol Cell
Title: EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.
Volume: 64
Issue: 4
Pages: 645-658
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Protein
Q7TNS8
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
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Protein Domain
IPR027971 | EPOP
Type: Family
Description: In mouse embryonic stem cells (mESCs), the transcriptional network can be divided into three functionally distinct modules: Polycomb, Core, and Myc, and the Polycomb module represses developmental genes []. This family includes the polycomb repressive complex 2-associated factor EPOP (Elongin BC and Polycomb Repressive Complex 2 (PRC2) Associated Protein, also termed C17orf96, esPRC2p48, E130012A19Rik), a scaffold protein expressed in the inner cell mass of the mouse blastocyst serving as a bridging partner between the PRC2/EED-EZH2 complex and the elongin BC complex, and fine-tuning the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells. Both EPOP and Elongin BC are required to maintain low levels of expression at PRC2 genomic targets []. EPOP interacts with the H2B deubiquitinase USP7 to modulate transcriptional processes in mESCs similar to MYC [].Another member of the family is the uncharacterized SKI/DACH domain-containing protein 1.
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Publication
38453366 | J:348964
 
First Author: Amici DR
Year: 2024
Journal: Life Sci Alliance
Title: Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life.
Volume: 7
Issue: 5
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Publication
34113809 | J:354990
First Author: Maat H
Year: 2021
Journal: iScience
Title: The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia.
Volume: 24
Issue: 5
Pages: 102435
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Publication
38123574 | J:360034
First Author: Cheron J
Year: 2023
Journal: Nat Commun
Title: USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder.
Volume: 14
Issue: 1
Pages: 8481
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Publication
36753544 | J:341706
First Author: Wu Y
Year: 2023
Journal: Sci Adv
Title: Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis.
Volume: 9
Issue: 6
Pages: eade5584
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Publication
36759621 | J:340160
First Author: Lu H
Year: 2023
Journal: Nat Commun
Title: Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.
Volume: 14
Issue: 1
Pages: 731
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Publication
32644293 | J:297332
First Author: Yang J
Year: 2020
Journal: EMBO Rep
Title: The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation.
Volume: 21
Issue: 9
Pages: e50308
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Publication
36952348 | J:334480
First Author: Hu H
Year: 2023
Journal: Cell Rep
Title: The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis.
Volume: 42
Issue: 4
Pages: 112288
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Publication
25086746 | J:219385
First Author: Zhang P
Year: 2014
Journal: Nat Cell Biol
Title: ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.
Volume: 16
Issue: 9
Pages: 864-75
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Publication
27452504 | J:250926
First Author: Chen H
Year: 2016
Journal: Biochim Biophys Acta
Title: ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation.
Volume: 1859
Issue: 11
Pages: 1459-1469
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Protein
A0A1D5RLP5
Organism: Mus musculus/domesticus
Length: 37  
Fragment?: true
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Publication
37576597 | J:347820
 
First Author: Barbeito P
Year: 2023
Journal: Front Cell Dev Biol
Title: EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Volume: 11
Pages: 1190258
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Publication
28626083 | J:248474
First Author: Tacer KF
Year: 2017
Journal: Biochem J
Title: Cellular and disease functions of the Prader-Willi Syndrome gene MAGEL2.
Volume: 474
Issue: 13
Pages: 2177-2190
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Publication
34061780 | J:308508
 
First Author: Li C
Year: 2021
Journal: J Clin Invest
Title: TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Volume: 131
Issue: 14
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Protein
P54254
Organism: Mus musculus/domesticus
Length: 791  
Fragment?: false
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Protein
J3QPR1
Organism: Mus musculus/domesticus
Length: 799  
Fragment?: false
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Protein
P0C7T6
Organism: Mus musculus/domesticus
Length: 687  
Fragment?: false
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Protein
Q80YR3
Organism: Mus musculus/domesticus
Length: 822  
Fragment?: false
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Protein
Q9D479
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
E9PZL9
Organism: Mus musculus/domesticus
Length: 532  
Fragment?: false
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Protein
G3X9M2
Organism: Mus musculus/domesticus
Length: 909  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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