Type |
Details |
Score |
Publication |
First Author: |
Zengeler KE |
Year: |
2022 |
Journal: |
Brain Behav Immun |
Title: |
SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology. |
Volume: |
108 |
|
Pages: |
80-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menke DB |
Year: |
2002 |
Journal: |
Gene Expr Patterns |
Title: |
Sexually dimorphic gene expression in the developing mouse gonad. |
Volume: |
2 |
Issue: |
3-4 |
Pages: |
359-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang F |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice. |
Volume: |
9 |
|
Pages: |
642931 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo G |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
Volume: |
18 |
Issue: |
4 |
Pages: |
675-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1212
 |
Fragment?: |
false |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Histone demethylase UTY |
Type: |
chain |
End: |
1212 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1149
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1211
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
100
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1111
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
646
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
144
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1212
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
78
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7366939 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-10-25 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736321 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7366969 |
Age: |
embryonic day 13.5 |
Image: |
1-S1B,E |
Note: |
More abundantly expressed than Kdm6a and Uty in both palate mesenchymal and epithelial cells. |
Specimen Label: |
1-S1B,E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7366939 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-10-25 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7366969 |
Age: |
embryonic day 13.5 |
Image: |
1-S1B,E |
Note: |
More abundantly expressed than Kdm6a and Uty in both palate mesenchymal and epithelial cells. |
Specimen Label: |
1-S1B,E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Grbavec D |
Year: |
1999 |
Journal: |
Biochem J |
Title: |
Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms. |
Volume: |
337 ( Pt 1) |
|
Pages: |
13-7 |
|
•
•
•
•
•
|
Allele |
Name: |
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Paul S Burgoyne |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, congenic, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Walport LJ |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase. |
Volume: |
289 |
Issue: |
26 |
Pages: |
18302-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams K |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e96545 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agger K |
Year: |
2009 |
Journal: |
Genes Dev |
Title: |
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence. |
Volume: |
23 |
Issue: |
10 |
Pages: |
1171-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang D |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix. |
Volume: |
288 |
Issue: |
47 |
Pages: |
33530-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamikawa YF |
Year: |
2014 |
Journal: |
Epigenetics |
Title: |
The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated. |
Volume: |
9 |
Issue: |
6 |
Pages: |
834-41 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents lysine-specific demethylase 6B (also known as JMJD3 or KDM6B). UTX (also known as KDM6A), JMJD3 (also known as KDM6B) and UTY (also known as KDM6C) are the members of the JmjC (Jumonji C) subfamily of the histone lysine demethylases family (KDM). They are histone demethylases that catalyse demethylation of H3K27, a mark important for transcriptional repression []. Unlike KDM6A, KDM6B is highly regulated at the transcriptional level and is upregulated in response to oncogenic stress [, ]. It is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner []. It also plays important roles in osteoblast differentiation and regulates the expressions of bone sialoprotein and osteocalcin via transcription factors Runx2 and osterix []. Its subcellular localisation is dynamically regulated and has pivotal roles for H3K27me3 status []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Andricovich J |
Year: |
2018 |
Journal: |
Cancer Cell |
Title: |
Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. |
Volume: |
33 |
Issue: |
3 |
Pages: |
512-526.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gozdecka M |
Year: |
2018 |
Journal: |
Nat Genet |
Title: |
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. |
Volume: |
50 |
Issue: |
6 |
Pages: |
883-894 |
|
•
•
•
•
•
|
Publication |
First Author: |
Welstead GG |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. |
Volume: |
109 |
Issue: |
32 |
Pages: |
13004-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mozhui K |
Year: |
2012 |
Journal: |
Front Neurosci |
Title: |
Sex-specific modulation of gene expression networks in murine hypothalamus. |
Volume: |
6 |
|
Pages: |
63 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1641
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Royo H |
Year: |
2010 |
Journal: |
Curr Biol |
Title: |
Evidence that meiotic sex chromosome inactivation is essential for male fertility. |
Volume: |
20 |
Issue: |
23 |
Pages: |
2117-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scott D |
Year: |
1997 |
Journal: |
Genet Res |
Title: |
Identification of H-Y epitopes in Smcy and other genes mapping to the mouse Y Chromosome short arm |
Volume: |
70 |
Issue: |
1 |
Pages: |
80-1 (Abstr.) |
|
•
•
•
•
•
|
Publication |
First Author: |
Vernet N |
Year: |
2011 |
Journal: |
Curr Biol |
Title: |
The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice. |
Volume: |
21 |
Issue: |
9 |
Pages: |
787-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1617-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
1999 |
Journal: |
Methods Enzymol |
Title: |
High-efficiency full-length cDNA cloning. |
Volume: |
303 |
|
Pages: |
19-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata K |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1757-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama S |
Year: |
2005 |
Journal: |
Science |
Title: |
Antisense transcription in the mammalian transcriptome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1564-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
•
•
|