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Search results 101 to 163 out of 163 for Vps29

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0.045s
Type Details Score
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Allele    
Name: VPS29 retromer complex component; wild type
Allele  
Name: VPS29 retromer complex component; gene trap OST17630, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST18210, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST24044, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST28280, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST93118, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST98823, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST113533, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST127837, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST135740, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST309649, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST405406, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST456377, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap OST471276, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: VPS29 retromer complex component; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: VPS29 retromer complex component; endonuclease-mediated mutation 3, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: VPS29 retromer complex component; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Strain
Attribute String: mutant stock, gene trap
Allele  
Name: VPS29 retromer complex component; gene trap IST13632H9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: VPS29 retromer complex component; gene trap IST14664C1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele
Name: VPS29 retromer complex component; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Swarbrick JD
Year: 2011
Journal: PLoS One
Title: VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins.
Volume: 6
Issue: 5
Pages: e20420
Strain
Attribute String: coisogenic
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Vps29/Vps29
Background: C57BL/6N-Vps29/BayMmucd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Vps29/Vps29<+>
Background: C57BL/6N-Vps29/BayMmucd
Zygosity: ht
Has Mutant Allele: true
GO Term
Protein
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
Protein Domain
Type: Family
Description: This entry represents vacuolar protein sorting-associated protein 35 (Vps35) from eukaryotes.Vps35 is a core component of the retromer complex which functions in the endosome-to-Golgi retrieval cargo transport pathway [, ]. Vps35 is part of the a cargo-selective complex trimer (CSC) of the retromer, which is composed of Vps26, Vps29 and Vps35 and is responsible for binding to and sorting protein cargo []. Mutations in the Vps35 gene have been linked to Parkinson's disease []. Structurally, VPS35 forms a horseshoe-shaped, right-handed, α-helical solenoid [].
Publication
First Author: Seaman MN
Year: 1997
Journal: J Cell Biol
Title: Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.
Volume: 137
Issue: 1
Pages: 79-92
Protein Domain
Type: Family
Description: Members of this largely uncharacterised family share a motif approximating DXH(X25)GDXXD(X25)GNHD as found in several phosphoesterases, including the nucleases SbcD and Mre11, and a family of uncharacterised archaeal putative phosphoesterases. In this family, the His residue in GNHD portion of the motif is not conserved. The member MJ0936, one of two from Methanocaldococcus jannaschii (Methanococcus jannaschii), was shown []to act on model phosphodiesterase substrates; a divalent cation was required. This entry also represents Vps29 which is part of the retromer complex in yeast [].This entry also includes vacuolar protein sorting-associated protein 29 (vps29), which is an essential component of the retromer complex, a conserved complex required in endosome-to-Golgi retrograde transport [].
Protein Domain
Type: Homologous_superfamily
Description: This superfamily represents the α-helical C-terminal domain found in vacuolar protein sorting-associated protein 35 (Vps35) from eukaryotes.Vps35 is a core component of the retromer complex which functions in the endosome-to-Golgi retrieval cargo transport pathway [, ]. Vps35 is part of the a cargo-selective complex trimer (CSC) of the retromer, which is composed of Vps26, Vps29 and Vps35 and is responsible for binding to and sorting protein cargo []. Mutations in the Vps35 gene have been linked to Parkinson's disease []. Structurally, VPS35 forms a horseshoe-shaped, right-handed, α-helical solenoid [].
Publication
First Author: Parra Bravo C
Year: 2024
Journal: Cell
Title: Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Volume: 187
Issue: 10
Pages: 2446-2464.e22
Publication
First Author: Reddy JV
Year: 2001
Journal: Mol Biol Cell
Title: Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval.
Volume: 12
Issue: 10
Pages: 3242-56
Publication
First Author: Hierro A
Year: 2007
Journal: Nature
Title: Functional architecture of the retromer cargo-recognition complex.
Volume: 449
Issue: 7165
Pages: 1063-7
Publication
First Author: Munsie LN
Year: 2015
Journal: Hum Mol Genet
Title: Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.
Volume: 24
Issue: 6
Pages: 1691-703
Publication
First Author: Fuse A
Year: 2015
Journal: FEBS Lett
Title: VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.
Volume: 589
Issue: 13
Pages: 1430-6
Publication
First Author: Seaman MN
Year: 2012
Journal: J Cell Sci
Title: The retromer complex - endosomal protein recycling and beyond.
Volume: 125
Issue: Pt 20
Pages: 4693-702
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 730  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 796  
Fragment?: false
Publication
First Author: Chen XQ
Year: 2023
Journal: Ann Neurol
Title: Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator.
Volume: 94
Issue: 2
Pages: 245-258
Publication  
First Author: Zhao Y
Year: 2021
Journal: Int J Mol Sci
Title: Expression of Low Level of VPS35-mCherry Fusion Protein Diminishes Vps35 Depletion Induced Neuron Terminal Differentiation Deficits and Neurodegenerative Pathology, and Prevents Neonatal Death.
Volume: 22
Issue: 16
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen S
Year: 2004
Journal: J Biol Chem
Title: Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii.
Volume: 279
Issue: 30
Pages: 31854-62
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory