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Search results 101 to 119 out of 119 for Vps41

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0.017s
Type Details Score
Allele
Name: VPS41 HOPS complex subunit; targeted mutation 1.1, Yoh Wada
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: VPS41 HOPS complex subunit; gene trap XS0589, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Strain
Attribute String: gene trap, mutant stock
Allele  
Name: VPS41 HOPS complex subunit; gene trap EUCE00123e06, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele  
Name: VPS41 HOPS complex subunit; gene trap EUCJ00133g04, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele  
Name: VPS41 HOPS complex subunit; gene trap IST15072F11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Strain
Attribute String: mutant strain, congenic, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, congenic, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Genotype
Symbol: Vps41/Vps41
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Vps41/Vps41
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
DO Term
Publication
First Author: Chassefeyre R
Year: 2021
Journal: Sci Adv
Title: Endosomal sorting drives the formation of axonal prion protein endoggresomes.
Volume: 7
Issue: 52
Pages: eabg3693
Protein Domain
Type: Family
Description: This entry includes Vps41 and Vps8.Vps41 is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport [, , ].Vps8 is one of the Golgi complex components necessary for vacuolar sorting []. Eukaryotic cells contain a highly dynamic endomembrane system, in which individual organelles keep their identity despite continuous vesicle generation and fusion. Vesicles that bud from a donor membrane are targeted and delivered to each individual organelle, where they release their cargo after fusion with the acceptor membrane. Vps8 is the core component of the endosomal tethering complex CORVET (class C core vacuole/endosome tethering). Vps8 co-operates with Vps21-GTP to mediate endosomal clustering in a reaction that is dependent on Vps3. Vps8 is the only CORVET subunit that is enriched on late endosomes, suggesting that it is a marker for the maturation of late endosomes. Late endosomes form intraluminal vesicles, and the resulting multivesicular bodies fuse with the vacuole to release their cargoes [].
Publication
First Author: Chen YJ
Year: 1996
Journal: Eur J Cell Biol
Title: The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae.
Volume: 70
Issue: 4
Pages: 289-97
Publication
First Author: Markgraf DF
Year: 2009
Journal: Mol Biol Cell
Title: The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments.
Volume: 20
Issue: 24
Pages: 5276-89
Protein
Organism: Mus musculus/domesticus
Length: 604  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7