| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:4417246 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754623 |
| Pattern: |
Single cells |
| Stage: |
TS23 |
| Assay Id: |
MGI:4829175 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011671_20 |
|
| Specimen Label: |
euxassay_011671_20 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4417246 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754623 |
| Pattern: |
Single cells |
| Stage: |
TS23 |
| Assay Id: |
MGI:4829175 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011671_21 |
|
| Specimen Label: |
euxassay_011671_21 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang S |
| Year: |
2006 |
| Journal: |
PLoS Genet |
| Title: |
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
e15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quiel A |
| Year: |
2012 |
| Journal: |
Biosens Bioelectron |
| Title: |
Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip. |
| Volume: |
36 |
| Issue: |
1 |
| Pages: |
207-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bailey PJ |
| Year: |
2006 |
| Journal: |
Exp Cell Res |
| Title: |
A global genomic transcriptional code associated with CNS-expressed genes. |
| Volume: |
312 |
| Issue: |
16 |
| Pages: |
3108-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2012 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
|
| Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bedogni F |
| Year: |
2021 |
| Journal: |
Front Mol Neurosci |
| Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
| Volume: |
14 |
|
| Pages: |
686034 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Serine/threonine-protein kinase VRK2 |
| Type: |
chain |
| End: |
503 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blanco S |
| Year: |
2008 |
| Journal: |
PLoS One |
| Title: |
Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein. |
| Volume: |
3 |
| Issue: |
2 |
| Pages: |
e1660 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vázquez-Cedeira M |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2. |
| Volume: |
287 |
| Issue: |
51 |
| Pages: |
42739-50 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
503
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
454
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
163
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
111
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Valbuena A |
| Year: |
2008 |
| Journal: |
PLoS One |
| Title: |
The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. |
| Volume: |
3 |
| Issue: |
7 |
| Pages: |
e2649 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernández IF |
| Year: |
2012 |
| Journal: |
Cell Mol Life Sci |
| Title: |
VRK2 anchors KSR1-MEK1 to endoplasmic reticulum forming a macromolecular complex that compartmentalizes MAPK signaling. |
| Volume: |
69 |
| Issue: |
22 |
| Pages: |
3881-93 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
4 |
| Description: |
Phosphoserine; by VRK1 and VRK2 |
| Type: |
modified residue |
| End: |
4 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
3 |
| Description: |
Phosphothreonine; by VRK1 and VRK2 |
| Type: |
modified residue |
| End: |
3 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
2 |
| Description: |
Phosphothreonine; by VRK1 and VRK2 |
| Type: |
modified residue |
| End: |
2 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
184 |
| Description: |
Phosphoserine; by VRK1 and VRK2 |
| Type: |
modified residue |
| End: |
184 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
21 |
| Description: |
Phosphothreonine; by CK1, VRK1 and VRK2 |
| Type: |
modified residue |
| End: |
21 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2. |
|
•
•
•
•
•
|
| Allele |
| Name: |
vaccinia related kinase 2; endonuclease-mediated mutation 9, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vrk2/Vrk2 |
| Background: |
C57BL/6J-Vrk2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu B |
| Year: |
2003 |
| Journal: |
Biol Reprod |
| Title: |
Late onset of spermatogenesis and gain of fertility in POG-deficient mice indicate that POG is not necessary for the proliferation of spermatogonia. |
| Volume: |
69 |
| Issue: |
1 |
| Pages: |
161-8 |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fanconi anemia, complementation group L; germ cell deficient |
| Allele Type: |
Transgenic |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pellas TC |
| Year: |
1991 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Germ-cell deficient (gcd), an insertional mutation manifested as infertility in transgenic mice. |
| Volume: |
88 |
| Issue: |
19 |
| Pages: |
8787-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duncan M |
| Year: |
1993 |
| Journal: |
Biol Reprod |
| Title: |
Germ cell deficient (gcd) mouse as a model of premature ovarian failure. |
| Volume: |
49 |
| Issue: |
2 |
| Pages: |
221-7 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: C57BL/6J * CBA/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
B6.Cg-Fancl/Ceb |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: C57BL/6 * FVB |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: C57BL/6J * CBA/J * FVB/N |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: 129/Sv * C57BL/6 * FVB/N |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: 129S7/SvEvBrd * C57BL/6J * CBA |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fancl/Fancl |
| Background: |
involves: 129/Sv * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yin Y |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells. |
| Volume: |
116 |
| Issue: |
41 |
| Pages: |
20528-20538 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2023 |
| Journal: |
Exp Mol Med |
| Title: |
Elevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice. |
| Volume: |
55 |
| Issue: |
10 |
| Pages: |
2162-2176 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Naz RK |
| Year: |
2005 |
| Journal: |
Front Biosci |
| Title: |
Gene knockouts that cause female infertility: search for novel contraceptive targets. |
| Volume: |
10 |
|
| Pages: |
2447-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Church DM |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e1000112 |
|
•
•
•
•
•
|