Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3716096 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-07-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1707419 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3716341 |
Age: |
embryonic day 11.5 |
Image: |
8 Wnt1 +/+ medial |
Note: |
Expression in cerebellar precursor cells in the rhombic lip and midline isthmus organizer. |
Specimen Label: |
8 Wnt1 +/+ medial |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3716096 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-07-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1707419 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3716341 |
Age: |
embryonic day 11.5 |
Image: |
8 Wnt1 nur12 lateral |
Note: |
Grossly normal expression patterns in rhombic lip and midline isthmic organizer. |
Specimen Label: |
8 Wnt1 nur12 lateral |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3716096 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-07-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1707419 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3716341 |
Age: |
embryonic day 11.5 |
Image: |
8 Wnt1 nur12 medial |
Note: |
Grossly normal expression patterns in rhombic lip and midline isthmic organizer. |
Specimen Label: |
8 Wnt1 nur12 medial |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3513357 |
Assay Type: |
RT-PCR |
Annotation Date: |
2005-01-10 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:360453 |
|
Stage: |
TS03 |
Assay Id: |
MGI:3513377 |
Age: |
embryonic day 3.0 |
|
|
Specimen Label: |
Wnt1 |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3513357 |
Assay Type: |
RT-PCR |
Annotation Date: |
2005-01-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360465 |
|
Stage: |
TS05 |
Assay Id: |
MGI:3513396 |
Age: |
embryonic day 4.0 |
|
|
Specimen Label: |
Wnt1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5445423 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-12-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3639222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5445529 |
Age: |
embryonic day 14.5 |
Image: |
2 |
|
Specimen Label: |
Wnt1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Navarro-Garberi M |
Year: |
2016 |
Journal: |
Brain Struct Funct |
Title: |
Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis. |
Volume: |
221 |
Issue: |
7 |
Pages: |
3693-708 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
370
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
370
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
De Ferrari GV |
Year: |
2000 |
Journal: |
Brain Res Brain Res Rev |
Title: |
Wnt signaling function in Alzheimer's disease. |
Volume: |
33 |
Issue: |
1 |
Pages: |
1-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peifer M |
Year: |
2000 |
Journal: |
Science |
Title: |
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. |
Volume: |
287 |
Issue: |
5458 |
Pages: |
1606-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semënov MV |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Human dishevelled genes constitute a DHR-containing multigene family. |
Volume: |
42 |
Issue: |
2 |
Pages: |
302-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bejsovec A |
Year: |
1999 |
Journal: |
Curr Biol |
Title: |
Wnt signalling shows its versatility. |
Volume: |
9 |
Issue: |
18 |
Pages: |
R684-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kestler HA |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
Generating a Wnt switch: it's all about the right dosage. |
Volume: |
193 |
Issue: |
3 |
Pages: |
431-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luther J |
Year: |
2018 |
Journal: |
Sci Transl Med |
Title: |
Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand. |
Volume: |
10 |
Issue: |
466 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang F |
Year: |
2021 |
Journal: |
Bone |
Title: |
Osteoblastic Wnt1 regulates periosteal bone formation in adult mice. |
Volume: |
143 |
|
Pages: |
115754 |
|
•
•
•
•
•
|
Publication |
First Author: |
Keupp K |
Year: |
2013 |
Journal: |
Am J Hum Genet |
Title: |
Mutations in WNT1 cause different forms of bone fragility. |
Volume: |
92 |
Issue: |
4 |
Pages: |
565-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Gregorio R |
Year: |
2018 |
Journal: |
Stem Cell Reports |
Title: |
miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation. |
Volume: |
10 |
Issue: |
4 |
Pages: |
1237-1250 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kapoun AM |
Year: |
1997 |
Journal: |
Oncogene |
Title: |
Preferential activation of Fgf8 by proviral insertion in mammary tumors of Wnt1 transgenic mice. |
Volume: |
14 |
Issue: |
24 |
Pages: |
2985-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang J |
Year: |
2013 |
Journal: |
Development |
Title: |
Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development. |
Volume: |
140 |
Issue: |
6 |
Pages: |
1342-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joeng KS |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis. |
Volume: |
127 |
Issue: |
7 |
Pages: |
2678-2688 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panhuysen M |
Year: |
2004 |
Journal: |
Mol Cell Neurosci |
Title: |
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region. |
Volume: |
26 |
Issue: |
1 |
Pages: |
101-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cornell B |
Year: |
2016 |
Journal: |
BMC Res Notes |
Title: |
Deficiency of 14-3-3ε and 14-3-3ζ by the Wnt1 promoter-driven Cre recombinase results in pigmentation defects. |
Volume: |
9 |
|
Pages: |
180 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajima M |
Year: |
2011 |
Journal: |
Brain Res |
Title: |
Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages. |
Volume: |
1382 |
|
Pages: |
275-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cicchini M |
Year: |
2014 |
Journal: |
Autophagy |
Title: |
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. |
Volume: |
10 |
Issue: |
11 |
Pages: |
2036-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawson LY |
Year: |
2022 |
Journal: |
FASEB J |
Title: |
Loading-induced bone formation is mediated by Wnt1 induction in osteoblast-lineage cells. |
Volume: |
36 |
Issue: |
9 |
Pages: |
e22502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dietrich P |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages. |
Volume: |
18 |
Issue: |
1 |
Pages: |
142-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown A |
Year: |
2011 |
Journal: |
J Comp Neurol |
Title: |
Molecular organization and timing of Wnt1 expression define cohorts of midbrain dopamine neuron progenitors in vivo. |
Volume: |
519 |
Issue: |
15 |
Pages: |
2978-3000 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joeng KS |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
The swaying mouse as a model of osteogenesis imperfecta caused by WNT1 mutations. |
Volume: |
23 |
Issue: |
15 |
Pages: |
4035-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang F |
Year: |
2019 |
Journal: |
J Bone Miner Res |
Title: |
Mesenchymal Cell-Derived Juxtacrine Wnt1 Signaling Regulates Osteoblast Activity and Osteoclast Differentiation. |
Volume: |
34 |
Issue: |
6 |
Pages: |
1129-1142 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yorgan TA |
Year: |
2020 |
Journal: |
J Bone Miner Res |
Title: |
Mice Carrying a Ubiquitous R235W Mutation of Wnt1 Display a Bone-Specific Phenotype. |
Volume: |
35 |
Issue: |
9 |
Pages: |
1726-1737 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo C |
Year: |
2007 |
Journal: |
Development |
Title: |
Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice. |
Volume: |
134 |
Issue: |
2 |
Pages: |
317-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagan N |
Year: |
2012 |
Journal: |
Mol Cell Neurosci |
Title: |
Wnt1 expression temporally allocates upper rhombic lip progenitors and defines their terminal cell fate in the cerebellum. |
Volume: |
49 |
Issue: |
2 |
Pages: |
217-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rochat A |
Year: |
2004 |
Journal: |
Mol Biol Cell |
Title: |
Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy. |
Volume: |
15 |
Issue: |
10 |
Pages: |
4544-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar R |
Year: |
2010 |
Journal: |
Cancer Res |
Title: |
Metastasis-associated protein 1 and its short form variant stimulates Wnt1 transcription through promoting its derepression from Six3 corepressor. |
Volume: |
70 |
Issue: |
16 |
Pages: |
6649-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2020 |
Journal: |
Cell Death Differ |
Title: |
Cumulative inactivation of Nell-1 in Wnt1 expressing cell lineages results in craniofacial skeletal hypoplasia and postnatal hydrocephalus. |
Volume: |
27 |
Issue: |
4 |
Pages: |
1415-1430 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ligon KL |
Year: |
2003 |
Journal: |
Development |
Title: |
Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. |
Volume: |
130 |
Issue: |
10 |
Pages: |
2275-87 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930287 |
Assay Type: |
RNA in situ |
Annotation Date: |
2001-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1698121 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:1930310 |
Age: |
embryonic day 13.5 |
Image: |
6 C |
Note: |
A dorsal mesencephalic stripe of Wnt1 expression. |
Specimen Label: |
6 C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1336675 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614814 |
Pattern: |
Regionally restricted |
Stage: |
TS14 |
Assay Id: |
MGI:1336676 |
Age: |
embryonic day 9.0 |
Image: |
E9.0 |
Note: |
Wnt1 is expressed in the dorsal myelencephalon. |
Specimen Label: |
E9.0 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1336675 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1708219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:1336676 |
Age: |
embryonic day 11.5 |
Image: |
E11.5 |
Note: |
Wnt1 is expressed in the dorsal myelencephalon. |
Specimen Label: |
E11.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1336675 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689619 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:1336676 |
Age: |
embryonic day 11.5 |
Image: |
E11.5 |
Note: |
Wnt1 is expressed in the caudal diencephalon. |
Specimen Label: |
E11.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang F |
Year: |
2022 |
Journal: |
Bone |
Title: |
Mesenchymal cell-derived Wnt1 signaling regulates subchondral bone remodeling but has no effects on the development of growth plate or articular cartilage in mice. |
Volume: |
163 |
|
Pages: |
116497 |
|
•
•
•
•
•
|
Publication |
First Author: |
L'episcopo F |
Year: |
2011 |
Journal: |
Mol Neurodegener |
Title: |
A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. |
Volume: |
6 |
|
Pages: |
49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taniguchi Y |
Year: |
2011 |
Journal: |
J Anat |
Title: |
Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube. |
Volume: |
219 |
Issue: |
5 |
Pages: |
589-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Company V |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus. |
Volume: |
9 |
|
Pages: |
755729 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6191561 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Wnt1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6191561 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Wnt1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191561 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Wnt1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191561 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Wnt1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191561 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Wnt1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191561 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Wnt1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191561 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Wnt1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:11942 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614012 |
Pattern: |
Regionally restricted |
Stage: |
TS12 |
Assay Id: |
MGI:1327259 |
Age: |
embryonic day 8.0 |
Image: |
8E |
Note: |
Wnt1 is expressed in a weak and broad domain in the mesencephalon of wild-type embryos. |
Specimen Label: |
8E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328384 |
Assay Type: |
RNA in situ |
Annotation Date: |
2001-08-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608912 |
Pattern: |
Not Specified |
Stage: |
TS12 |
Assay Id: |
MGI:2148283 |
Age: |
embryonic day 8.0 |
|
Note: |
Authors state that Wnt1 expression is faint in double mutants at the 4-somite stage. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6438098 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-07-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757720 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6438114 |
Age: |
embryonic day 12.5 |
|
Note: |
In the cervical region, the Wnt1 expression domain was partially included in the Atoh1 expression domain. |
Specimen Label: |
4C6 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:11942 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1616412 |
Pattern: |
Regionally restricted |
Stage: |
TS12 |
Assay Id: |
MGI:1327259 |
Age: |
embryonic day 8.0 |
Image: |
8F |
Note: |
Wnt1 is expressed in the dorsal neural tube and in a transverse band in the posterior mesencephalon of wild-type embryos. |
Specimen Label: |
8F |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:11942 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608912 |
Pattern: |
Regionally restricted |
Stage: |
TS12 |
Assay Id: |
MGI:1327259 |
Age: |
embryonic day 8.0 |
Image: |
8F |
Note: |
Wnt1 is expressed in the dorsal neural tube and in a transverse band in the posterior mesencephalon of wild-type embryos. |
Specimen Label: |
8F |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6438098 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-07-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757720 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6438114 |
Age: |
embryonic day 12.5 |
|
Note: |
Expression was detected in the dorsal midline. Compared to staining in an adjacent section, the Wnt1 expression domain was partially included in the Atoh1 expression domain. |
Specimen Label: |
4C3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu X |
Year: |
2014 |
Journal: |
Nucl Recept Signal |
Title: |
Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transitions. |
Volume: |
12 |
|
Pages: |
e004 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-07-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697919 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7664447 |
Age: |
embryonic day 11.5 |
Image: |
3t |
Note: |
Ventricular zone expression was detected along a transverse line aligned precisely with the IMB (isthmo-mesencephalic transverse boundary), that is, in between the evaginated Fgf8-positive isthmus and the sulcal midbrain area (both of which lacked Wnt1 signal). |
Specimen Label: |
3t |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186853 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-07-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697919 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:7664447 |
Age: |
embryonic day 11.5 |
Image: |
3s |
Note: |
Ventricular zone expression was detected along a transverse line aligned precisely with the IMB (isthmo-mesencephalic transverse boundary), that is, in between the evaginated Fgf8-positive isthmus and the sulcal midbrain area (both of which lacked Wnt1 signal). |
Specimen Label: |
3s |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rota LM |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors. |
Volume: |
74 |
Issue: |
19 |
Pages: |
5668-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serbedzija GN |
Year: |
1996 |
Journal: |
J Neurobiol |
Title: |
Cell death in the CNS of the Wnt-1 mutant mouse. |
Volume: |
31 |
Issue: |
3 |
Pages: |
275-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brewer S |
Year: |
2004 |
Journal: |
Dev Biol |
Title: |
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. |
Volume: |
267 |
Issue: |
1 |
Pages: |
135-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
McMahon AP |
Year: |
1990 |
Journal: |
Cell |
Title: |
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. |
Volume: |
62 |
Issue: |
6 |
Pages: |
1073-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mastick GS |
Year: |
1996 |
Journal: |
J Comp Neurol |
Title: |
Early deletion of neuromeres in Wnt-1-/- mutant mice: evaluation by morphological and molecular markers. |
Volume: |
374 |
Issue: |
2 |
Pages: |
246-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsukamoto AS |
Year: |
1988 |
Journal: |
Cell |
Title: |
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. |
Volume: |
55 |
Issue: |
4 |
Pages: |
619-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin TP |
Year: |
1992 |
Journal: |
Cancer Res |
Title: |
Role of endocrine, autocrine, and paracrine interactions in the development of mammary hyperplasia in Wnt-1 transgenic mice. |
Volume: |
52 |
Issue: |
16 |
Pages: |
4413-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2000 |
Journal: |
Oncogene |
Title: |
Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. |
Volume: |
19 |
Issue: |
8 |
Pages: |
1002-9 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Publication |
First Author: |
McMahon AP |
Year: |
1992 |
Journal: |
Cell |
Title: |
The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. |
Volume: |
69 |
Issue: |
4 |
Pages: |
581-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2015 |
Journal: |
Neurobiol Dis |
Title: |
A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice. |
Volume: |
82 |
|
Pages: |
32-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao R |
Year: |
2024 |
Journal: |
Elife |
Title: |
Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination. |
Volume: |
13 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MacArthur CA |
Year: |
1995 |
Journal: |
J Virol |
Title: |
Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis. |
Volume: |
69 |
Issue: |
4 |
Pages: |
2501-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shackleford GM |
Year: |
1993 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4. |
Volume: |
90 |
Issue: |
2 |
Pages: |
740-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao H |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis. |
Volume: |
65 |
Issue: |
15 |
Pages: |
6864-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baker R |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
Pea3 transcription factors and wnt1-induced mouse mammary neoplasia. |
Volume: |
5 |
Issue: |
1 |
Pages: |
e8854 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teissedre B |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors. |
Volume: |
4 |
Issue: |
2 |
Pages: |
e4537 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HY |
Year: |
2004 |
Journal: |
Science |
Title: |
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. |
Volume: |
303 |
Issue: |
5660 |
Pages: |
1020-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lavado A |
Year: |
2008 |
Journal: |
Development |
Title: |
Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. |
Volume: |
135 |
Issue: |
3 |
Pages: |
441-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andersson ER |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. |
Volume: |
110 |
Issue: |
7 |
Pages: |
E602-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Danielian PS |
Year: |
1998 |
Journal: |
Curr Biol |
Title: |
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. |
Volume: |
8 |
Issue: |
24 |
Pages: |
1323-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Glover CE |
Year: |
2009 |
Journal: |
Carcinogenesis |
Title: |
Endocrine dysfunction in p27Kip1 deficient mice and susceptibility to Wnt-1 driven breast cancer. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1058-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu T |
Year: |
2000 |
Journal: |
J Neurobiol |
Title: |
Spatial and temporal changes in natural and target deprivation-induced cell death in the mouse inferior olive. |
Volume: |
43 |
Issue: |
1 |
Pages: |
18-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Danielian PS |
Year: |
1997 |
Journal: |
Dev Biol |
Title: |
A 5.5-kb enhancer is both necessary and sufficient for regulation of Wnt-1 transcription in vivo. |
Volume: |
192 |
Issue: |
2 |
Pages: |
300-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prakash N |
Year: |
2006 |
Journal: |
Development |
Title: |
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. |
Volume: |
133 |
Issue: |
1 |
Pages: |
89-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu Q |
Year: |
2024 |
Journal: |
Gastroenterology |
Title: |
Sacral Neural Crest-Independent Origin of the Enteric Nervous System in Mouse. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fu J |
Year: |
2011 |
Journal: |
Dev Dyn |
Title: |
Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. |
Volume: |
240 |
Issue: |
2 |
Pages: |
365-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang A |
Year: |
2017 |
Journal: |
Oncotarget |
Title: |
MiR-34a promotes DCs development and inhibits their function on T cell activation by targeting WNT1. |
Volume: |
8 |
Issue: |
10 |
Pages: |
17191-17201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ellisor D |
Year: |
2009 |
Journal: |
Gene Expr Patterns |
Title: |
Comparative analysis of conditional reporter alleles in the developing embryo and embryonic nervous system. |
Volume: |
9 |
Issue: |
7 |
Pages: |
475-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mulroy T |
Year: |
2002 |
Journal: |
Eur J Immunol |
Title: |
Wnt-1 and Wnt-4 regulate thymic cellularity. |
Volume: |
32 |
Issue: |
4 |
Pages: |
967-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vendrell V |
Year: |
2013 |
Journal: |
Mech Dev |
Title: |
Roles of Wnt8a during formation and patterning of the mouse inner ear. |
Volume: |
130 |
Issue: |
2-3 |
Pages: |
160-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miranda M |
Year: |
2014 |
Journal: |
FEBS Lett |
Title: |
Identification of the WNT1 residues required for palmitoylation by Porcupine. |
Volume: |
588 |
Issue: |
24 |
Pages: |
4815-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamata T |
Year: |
2004 |
Journal: |
Biochim Biophys Acta |
Title: |
R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. |
Volume: |
1676 |
Issue: |
1 |
Pages: |
51-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broccoli D |
Year: |
1996 |
Journal: |
Mol Cell Biol |
Title: |
Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. |
Volume: |
16 |
Issue: |
7 |
Pages: |
3765-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Donehower LA |
Year: |
1995 |
Journal: |
Genes Dev |
Title: |
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. |
Volume: |
9 |
Issue: |
7 |
Pages: |
882-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Howe LR |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. |
Volume: |
276 |
Issue: |
23 |
Pages: |
20108-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Szeder V |
Year: |
2003 |
Journal: |
Dev Biol |
Title: |
Neural crest origin of mammalian Merkel cells. |
Volume: |
253 |
Issue: |
2 |
Pages: |
258-63 |
|
•
•
•
•
•
|