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Search results 101 to 138 out of 138 for Xcl1

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0.019s

Type

Details

Score

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

31578268 | J:282056

First Author:	Rezende RM
Year:	2019
Journal:	J Immunol
Title:	γδ T Cell-Secreted XCL1 Mediates Anti-CD3-Induced Oral Tolerance.
Volume:	203
Issue:	10
Pages:	2621-2629

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Protein

A0A4D6YWC7

Organism:	Mus musculus/domesticus
Length:	114
Fragment?:	false

•

Publication

30297531 | J:268244

First Author:	Sánchez-Paulete AR
Year:	2018
Journal:	Cancer Res
Title:	Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.
Volume:	78
Issue:	23
Pages:	6643-6654

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Publication

22100876 | -

First Author:	Lei Y
Year:	2012
Journal:	Microbes Infect
Title:	XCL1 and XCR1 in the immune system.
Volume:	14
Issue:	3
Pages:	262-7

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Publication

31026469 | -

First Author:	Xu F
Year:	2019
Journal:	Dev Comp Immunol
Title:	Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine rodents.
Volume:	98

Pages:	80-88

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Allele

Xcl1<em2Smoc> | MGI:7293199

Name:	chemokine (C motif) ligand 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:6429807 | C57BL/6JSmoc-Xcl1<em2Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Allele

Xcl1<tm1Ciphe> | MGI:6802138

Name:	chemokine (C motif) ligand 1; targeted mutation 1, Centre d'ImmunoPhenomique
Allele Type:	Targeted
Attribute String:	Reporter

•

Publication

37872423 | J:358284

First Author:	Lokwani R
Year:	2024
Journal:	Nat Mater
Title:	Pro-regenerative biomaterials recruit immunoregulatory dendritic cells after traumatic injury.
Volume:	23
Issue:	1
Pages:	147-157

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Publication

37883230 | J:351823

First Author:	First NJ
Year:	2023
Journal:	Cell Rep
Title:	Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection.
Volume:	42
Issue:	11
Pages:	113294

•

Publication

8849694 | -

First Author:	Yoshida T
Year:	1996
Journal:	FEBS Lett
Title:	Structure and expression of two highly related genes encoding SCM-1/human lymphotactin.
Volume:	395
Issue:	1
Pages:	82-8

•

Publication

25497737 | -

First Author:	Fox JC
Year:	2015
Journal:	Cytokine
Title:	Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily.
Volume:	71
Issue:	2
Pages:	302-11

•

Publication

24155383 | -

First Author:	Geyer H
Year:	2014
Journal:	J Virol
Title:	Cytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+ CD4- dendritic cells.
Volume:	88
Issue:	1
Pages:	292-302

•

Protein Domain

IPR008105 | Chemokine_XCL1/XCL2

Type:

Family

Description:

Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helpercells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).The C chemokine subfamily is composed of two members, XC chemokine ligand 1 (XCL1), also known as lymphotactin or SCM-1 alpha, and XC chemokine ligand 2 (XCL2), also known as SCM-1 beta []. The cognate receptor for these chemokines is XCR1 [].XCL1 is an inflammatory chemokine that produced by activated CD8+ T cells and natural killer cells. It is involved in the mediation of interactions between antigen-presenting dendritic cells and T-cells, and induction of CD8+ effector T-cell responses [, ]. It is also involved in the formation of self-tolerance mechanisms through the development of T regulatory cells within the thymus []. Less is known about its closely related paralogue XCL2, although the in vitro functional profiles are virtually identical []. Human XCL2 and XCL1 amino acid sequences differ at only two positions near the N terminus [].Viral XCL1 (vXCL1) exclusively binds to CD4(-) rat dendritic cells (DC), a subset of DC that express the corresponding chemokine receptor XCR1, a strategy to subvert cytotoxic immune responses [].

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Publication

26473289 | J:310951

First Author:	Chen SR
Year:	2015
Journal:	Oncotarget
Title:	Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling.
Volume:	6
Issue:	35
Pages:	37012-27

•

Publication

20479118 | J:163424

First Author:	Crozat K
Year:	2010
Journal:	J Exp Med
Title:	The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells.
Volume:	207
Issue:	6
Pages:	1283-92

•

Publication

38026988 | J:343239

First Author:	Bonnavion R
Year:	2023
Journal:	Front Pharmacol
Title:	Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5).
Volume:	14

Pages:	1297596

•

Publication

32948682 | J:303625

First Author:	Davenport B
Year:	2020
Journal:	J Immunol
Title:	Chemokine Signatures of Pathogen-Specific T Cells II: Memory T Cells in Acute and Chronic Infection.
Volume:	205
Issue:	8
Pages:	2188-2206

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Protein

P47993

Organism:	Mus musculus/domesticus
Length:	114
Fragment?:	false

•

Publication

9689100 | J:49070

First Author:	Ma Q
Year:	1998
Journal:	Proc Natl Acad Sci U S A
Title:	Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.
Volume:	95
Issue:	16
Pages:	9448-53

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Publication

11544102 | -

First Author:	Horuk R
Year:	2001
Journal:	Cytokine Growth Factor Rev
Title:	Chemokine receptors.
Volume:	12
Issue:	4
Pages:	313-35

•

Publication

10601351 | -

First Author:	Charbonnier AS
Year:	1999
Journal:	J Exp Med
Title:	Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells.
Volume:	190
Issue:	12
Pages:	1755-68

•

Publication

9500790 | -

First Author:	Sallusto F
Year:	1998
Journal:	J Exp Med
Title:	Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes.
Volume:	187
Issue:	6
Pages:	875-83

•

Publication

7592998 | -

First Author:	Strieter RM
Year:	1995
Journal:	J Biol Chem
Title:	The functional role of the ELR motif in CXC chemokine-mediated angiogenesis.
Volume:	270
Issue:	45
Pages:	27348-57

•

Publication

10714678 | -

First Author:	Zlotnik A
Year:	2000
Journal:	Immunity
Title:	Chemokines: a new classification system and their role in immunity.
Volume:	12
Issue:	2
Pages:	121-7

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

11217851 | J:65060

First Author:	Kawai J
Year:	2001
Journal:	Nature
Title:	Functional annotation of a full-length mouse cDNA collection.
Volume:	409
Issue:	6821
Pages:	685-90

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Publication

11042159 | J:68323

First Author:	Carninci P
Year:	2000
Journal:	Genome Res
Title:	Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume:	10
Issue:	10
Pages:	1617-30

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Publication

10349636 | J:80645

First Author:	Carninci P
Year:	1999
Journal:	Methods Enzymol
Title:	High-efficiency full-length cDNA cloning.
Volume:	303

Pages:	19-44

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Publication

11076861 | J:68324

First Author:	Shibata K
Year:	2000
Journal:	Genome Res
Title:	RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume:	10
Issue:	11
Pages:	1757-71

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Publication

16141073 | -

First Author:	Katayama S
Year:	2005
Journal:	Science
Title:	Antisense transcription in the mammalian transcriptome.
Volume:	309
Issue:	5740
Pages:	1564-6

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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