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Search results 101 to 200 out of 962 for Xist

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Type Details Score
Publication
11230177 | J:68080
First Author: Newall AE
Year: 2001
Journal: Hum Mol Genet
Title: Primary non-random X inactivation associated with disruption of Xist promoter regulation.
Volume: 10
Issue: 6
Pages: 581-9
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Publication
21389056 | J:171502
First Author: Senner CE
Year: 2011
Journal: Development
Title: Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.
Volume: 138
Issue: 8
Pages: 1541-50
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Publication
32041873 | J:285716
First Author: Yang L
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut.
Volume: 117
Issue: 8
Pages: 4262-4272
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Publication
9099757 | J:39583
First Author: Komura Ji
Year: 1997
Journal: J Biol Chem
Title: In vivo ultraviolet and dimethyl sulfate footprinting of the 5' region of the expressed and silent Xist alleles.
Volume: 272
Issue: 16
Pages: 10975-80
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Publication
9660859 | J:48709
First Author: Clemson CM
Year: 1998
Journal: J Cell Biol
Title: Stabilization and localization of Xist RNA are controlled by separate mechanisms and are not sufficient for X inactivation.
Volume: 142
Issue: 1
Pages: 13-23
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Publication
11891913 | J:75352
First Author: Hartshorn C
Year: 2002
Journal: Mol Reprod Dev
Title: Developmentally-regulated changes of Xist RNA levels in single preimplantation mouse embryos, as revealed by quantitative real-time PCR.
Volume: 61
Issue: 4
Pages: 425-36
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Publication
18625719 | J:140238
First Author: Jonkers I
Year: 2008
Journal: Mol Cell Biol
Title: Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle.
Volume: 28
Issue: 18
Pages: 5583-94
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Publication
7529677 | J:21784
First Author: Buzin CH
Year: 1994
Journal: Development
Title: Quantitative RT-PCR assays show Xist RNA levels are low in mouse female adult tissue, embryos and embryoid bodies.
Volume: 120
Issue: 12
Pages: 3529-36
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Publication
8901053 | J:32250
First Author: Sado T
Year: 1996
Journal: Dev Dyn
Title: Mosaic methylation of Xist gene before chromosome inactivation in undifferentiated female mouse embryonic stem and embryonic germ cells.
Volume: 205
Issue: 4
Pages: 421-34
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Publication
26370508 | J:235842
First Author: Ohhata T
Year: 2015
Journal: Mol Cell Biol
Title: Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression.
Volume: 35
Issue: 22
Pages: 3909-20
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Publication
19036803 | J:142921
First Author: Hoki Y
Year: 2009
Journal: Development
Title: A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse.
Volume: 136
Issue: 1
Pages: 139-46
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Publication
30026327 | J:264293
First Author: Xing F
Year: 2018
Journal: Cancer Res
Title: Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis.
Volume: 78
Issue: 15
Pages: 4316-4330
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Publication
12420298 | J:81342
First Author: Hartshorn C
Year: 2003
Journal: Mol Reprod Dev
Title: Differential pattern of Xist RNA accumulation in single blastomeres isolated from 8-cell stage mouse embryos following laser zona drilling.
Volume: 64
Issue: 1
Pages: 41-51
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Publication
26267271 | J:226026
First Author: Deuve JL
Year: 2015
Journal: Epigenetics
Title: Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome.
Volume: 10
Issue: 10
Pages: 931-42
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Publication
24613346 | J:212497
First Author: Barakat TS
Year: 2014
Journal: Mol Cell
Title: The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing.
Volume: 53
Issue: 6
Pages: 965-78
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Publication
10431231 | J:75502
First Author: Csankovszki G
Year: 1999
Journal: Nat Genet
Title: Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation.
Volume: 22
Issue: 4
Pages: 323-4
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Publication
8678983 | J:34918
First Author: Rougeulle C
Year: 1996
Journal: Mamm Genome
Title: Identification of an S19 pseudogene lying close to the Xist sequence in the mouse.
Volume: 7
Issue: 8
Pages: 606-7
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Publication
10818211 | J:62513
First Author: Romer JT
Year: 2000
Journal: Mamm Genome
Title: The upstream region of the mouse xist gene contains two ribosomal protein pseudogenes.
Volume: 11
Issue: 6
Pages: 461-3
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Publication
25993097 | J:235416
First Author: Kamikawa YF
Year: 2015
Journal: PLoS One
Title: Histone demethylation maintains Prdm14 and Tsix expression and represses xIst in embryonic stem cells.
Volume: 10
Issue: 5
Pages: e0125626
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Publication
28143937 | J:240927
First Author: Sripathy S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.
Volume: 114
Issue: 7
Pages: 1619-1624
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Publication
10588721 | J:58918
First Author: Warshawsky D
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Further examination of the Xist promoter-switch hypothesis in X inactivation: evidence against the existence and function of a P(0) promoter.
Volume: 96
Issue: 25
Pages: 14424-9
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Publication
8922998 | J:36484
First Author: Simmler MC
Year: 1996
Journal: Hum Mol Genet
Title: A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich region containing a new testis specific gene Tsx.
Volume: 5
Issue: 11
Pages: 1713-26
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Publication
1423610 | J:3014
First Author: Brockdorff N
Year: 1992
Journal: Cell
Title: The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus.
Volume: 71
Issue: 3
Pages: 515-26
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Publication
- | J:26541
 
First Author: McCarrey J
Year: 1995
Journal: Isozyme Bulletin
Title: Differential methylation of the xist gene during gametogenesis correlates with the inheritance of imprinted alleles in the mouse.
Volume: 28
Pages: 40
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Publication
9545634 | J:46800
First Author: Debrand E
Year: 1998
Journal: Genomics
Title: Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.
Volume: 48
Issue: 3
Pages: 296-303
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Publication
16912274 | J:111681
First Author: Chaumeil J
Year: 2006
Journal: Genes Dev
Title: A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced.
Volume: 20
Issue: 16
Pages: 2223-37
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Publication
8601395 | J:31968
First Author: Mise N
Year: 1996
Journal: Exp Cell Res
Title: Activation of the inactive X chromosome induced by cell fusion between a murine EC and female somatic cell accompanies reproducible changes in the methylation pattern of the Xist gene.
Volume: 223
Issue: 2
Pages: 193-202
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Publication
29089420 | J:260468
First Author: Inoue A
Year: 2017
Journal: Genes Dev
Title: Genomic imprinting of Xist by maternal H3K27me3.
Volume: 31
Issue: 19
Pages: 1927-1932
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Publication
12045143 | J:77062
First Author: Chureau C
Year: 2002
Journal: Genome Res
Title: Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine.
Volume: 12
Issue: 6
Pages: 894-908
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Publication
16648467 | J:109073
First Author: Rowntree RK
Year: 2006
Journal: Mol Cell Biol
Title: Mapping of DNA replication origins to noncoding genes of the X-inactivation center.
Volume: 26
Issue: 10
Pages: 3707-17
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Gene
302873 | Ftx
Type: gene
Organism: rat
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Gene
102555331 | Jpx
Type: gene
Organism: rat
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GXD Expression
GXD Expression
Probe: MGI:7496095
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:318653
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:7496098
Age: embryonic day 2.5
Image: 7B m-/- 8-cell male
Note: Almost every nucleus exhibited ectopic Xist expression from and coating of the maternally-inherited X-chromosome (red).
Specimen Label: 7B m-/- 8-cell male
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Present
Sex: Female
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7331495
Age: embryonic day 8.5
Note: In female embryos at E8.5 abundant Xist RNA was detected from only one locus.
Specimen Label: Female E8.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7331495
Age: embryonic day 8.5
Note: The proportion of cells with low level Xist expression was no longer present at E8.5.
Specimen Label: Male E8.5
Detected: false
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:6259606
Assay Type: RNA in situ
Annotation Date: 2018-12-10
Strength: Present
Sex: Female
Emaps: EMAPS:3187710
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:6259643
Age: embryonic day 7.0
Image: S1C
Note: Expression of Xist partially overlaps with Atrx protein in 25% of trophoblast giant cells.
Specimen Label: S1C
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160466
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:6459735
Age: embryonic day 4.25
Image: 2d
Note: Most of the Trophectoderm/Extraembryonic Ectoderm cells (70-95%) had one Xist cloud and a single Tsix spot.
Specimen Label: 2d
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160508
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:6459735
Age: embryonic day 5.5
Image: 1g,i
Note: Encircled is a cell with two Xist clouds and a single Tsix signal.
Specimen Label: 1g,i
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160507
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:6459735
Age: embryonic day 4.75
Image: 1d,h
Note: Encircled is a single cell with two Xist clouds and a single Tsix signal.
Specimen Label: 1d,h
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6259606
Assay Type: RNA in situ
Annotation Date: 2018-12-10
Strength: Present
Sex: Female
Emaps: EMAPS:1603910
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:6259643
Age: embryonic day 7.0
Image: 1C
Note: Xist was detected in a single RNA domain in the overwhelming majority of cells.
Specimen Label: 1C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6259606
Assay Type: RNA in situ
Annotation Date: 2018-12-10
Strength: Present
Sex: Female
Emaps: EMAPS:1604210
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:6259643
Age: embryonic day 7.0
Image: 1B
Note: Xist was detected in a single RNA domain in the overwhelming majority of cells.
Specimen Label: 1B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Weak
Sex: Male
Emaps: EMAPS:1604211
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7331495
Age: embryonic day 7.5
Note: Male extraembryonic cells showed low level monoallelic or no Xist expression.
Specimen Label: Male extraembryonic E7.5
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160466
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:6459735
Age: embryonic day 4.5
Image: 2e
Note: Most of the Trophectoderm/Extraembryonic Ectoderm cells (70-95%) had one Xist cloud and a single Tsix spot.
Specimen Label: 2e
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Male
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 5B mz-/- male delayed
Note: A subset of nuclei (in much higher proportions, 20-60%) exhibited ectopic Xist RNA coating of their sole, maternally-inherited X-chromosome.
Specimen Label: 5B mz-/- male delayed
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:24701
Assay Type: RNA in situ
Annotation Date: 2022-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:160415
Pattern: Regionally restricted
Stage: TS05
Assay Id: MGI:7281465
Age: embryonic day 4.0
Note: A small proportion of cells contain no Xist RNA domain, and either one or two Xist/DXPas34 RNA pinpoint signals.
Specimen Label: 2O
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7496095
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:318653
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:7496098
Age: embryonic day 2.5
Image: 7A m-/- 8-cell female
Note: A high percentage of nuclei with Xist RNA expression and coating of both X-chromosomes (red and white).
Specimen Label: 7A m-/- 8-cell female
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 5A m-/- female
Note: Most nuclei displayed a single Xist RNA coat. A subset displayed Xist RNA coating of both X-chromosomes.
Specimen Label: 5A m-/- female
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 5A mz-/- female
Note: Most nuclei displayed a single Xist RNA coat. A subset displayed Xist RNA coating of both X-chromosomes.
Specimen Label: 5A mz-/- female
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Male
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 5B mz-/- male
Note: A subset of nuclei (few or no nuclei) exhibited ectopic Xist RNA coating of their sole, maternally-inherited X-chromosome.
Specimen Label: 5B mz-/- male
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160507
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:6459735
Age: embryonic day 5.0
Image: 2c
Note: Most of the cells (88-98%) in the primitive endoderm/visceral endoderm lineage had one Xist cloud per nucleus.
Specimen Label: 2c
Detected: true
Specimen Num: 7
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Publication
32439758 | J:290852
 
First Author: Postlmayr A
Year: 2020
Journal: Development
Title: Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.
Volume: 147
Issue: 11
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Publication
34722536 | J:312431
 
First Author: Matsuura R
Year: 2021
Journal: Front Cell Dev Biol
Title: Ectopic Splicing Disturbs the Function of Xist RNA to Establish the Stable Heterochromatin State.
Volume: 9
Pages: 751154
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 4A m-/- female
Note: A small percentage of nuclei with H3K27me3 enrichment coinciding with the Xist RNA coat, likely due to the expression of zygotic Eed.
Specimen Label: 4A m-/- female
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:6719339
Assay Type: RNA in situ
Annotation Date: 2023-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7495898
Age: embryonic day 3.5
Image: 4A mz-/- female
Note: But there was no nuclei with H3K27me3 enrichment coinciding with the Xist RNA coat, likely due to no expression of zygotic Eed.
Specimen Label: 4A mz-/- female
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160507
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:6459735
Age: embryonic day 5.0
Image: 1e
Note: Shown is a single cell with one Xist pinpoint signal and two Tsix signals. 26% of the epiblast cells showed weak Xist expression as a pinpoint signal.
Specimen Label: 1e
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:6459735
Age: embryonic day 3.75
Image: 1c
Note: Nuclear cloud signals began to disappear and cells showing biallelic expression of Tsix began to appear. Shown is a single cell with no Xist and a single Tsix signal.
Specimen Label: 1c
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Present
Sex: Female
Emaps: EMAPS:1603912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7331495
Age: embryonic day 8.0
Note: In female embryos at E8.0 a proportion of cells displayed differential biallelic Xist expression, but in the majority of cells abundant Xist RNA was detected from only one locus.
Specimen Label: Female E8.0
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Weak
Sex: Male
Emaps: EMAPS:1603910
Pattern: Regionally restricted
Stage: TS10
Assay Id: MGI:7331495
Age: embryonic day 7.0
Note: In males, two patterns of expression could be discerned. Low level monoallelic expression or cells didn't express any detectable Xist RNA. The proportion of cells with low level expression decreased over time.
Specimen Label: Male E7.0
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Weak
Sex: Male
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7331495
Age: embryonic day 7.5
Note: In males, two patterns of expression could be discerned. Low level monoallelic expression or cells didn't express any detectable Xist RNA. The proportion of cells with low level expression decreased over time.
Specimen Label: Male E7.5
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6259606
Assay Type: RNA in situ
Annotation Date: 2018-12-10
Strength: Present
Sex: Female
Emaps: EMAPS:1604210
Pattern: Regionally restricted
Stage: TS10
Assay Id: MGI:6259643
Age: embryonic day 7.0
Image: S1B
Note: There was no overlap of the Xist expression domain with the Atrx protein in the two nuclei from chorion shown in the figure. Only 5.8% of chorion nuclei show partial overlap of expression.
Specimen Label: S1B
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7496095
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7496098
Age: embryonic day 3.5
Image: 6A m-/- female
Note: Mosaic distribution of Xist RNA expression and coating: some expressed from and coating of the maternal-X (red), others from and coating of the paternal-X (white), or from both the maternal and paternal X-chromosomes.
Specimen Label: 6A m-/- female
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:24701
Assay Type: RNA in situ
Annotation Date: 2022-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:7281465
Age: embryonic day 3.5
Note: Most cells contain a Xist domain corresponding to the paternal X with no sign of DXPas34 RNA within such domains and a proportion of these cells also contain a Xist/DXPas34 RNA pinpoint signal.
Specimen Label: 2N
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:6459735
Age: embryonic day 3.5
Image: 1b
Note: More than 80% of inner cell mass cells had one Xist cloud and one pinpoint Tsix signal per nucleus. Shown is a single cell with one Xist cloud and a single Tsix signal.
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Present
Sex: Female
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7331495
Age: embryonic day 7.5
Note: In female embryos at E7.5 cells no longer showed low level biallelic Xist expression. A proportion of cells displayed differential biallelic Xist expression, and in the majority of cells, abundant Xist RNA was detected from only one locus.
Specimen Label: Female E7.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Weak
Sex: Male
Emaps: EMAPS:160399
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7331495
Age: embryonic day 6.5
Note: In males, two patterns of expression could be discerned. Low level monoallelic expression or cells didn't express any detectable Xist RNA. The proportion of cells with low level expression decreased over time.
Specimen Label: Male E6.5
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Weak
Sex: Male
Emaps: EMAPS:1603912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7331495
Age: embryonic day 8.0
Note: In males, two patterns of expression could be discerned. Low level monoallelic expression or cells didn't express any detectable Xist RNA. The proportion of cells with low level expression decreased over time.
Specimen Label: Male E8.0
Detected: true
Specimen Num: 13
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Publication
26477563 | J:227628
 
First Author: Sarkar MK
Year: 2015
Journal: Nat Commun
Title: An Xist-activating antisense RNA required for X-chromosome inactivation.
Volume: 6
Pages: 8564
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•
•
•
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GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Present
Sex: Female
Emaps: EMAPS:160399
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7331495
Age: embryonic day 6.5
Note: Female embryos showed three patterns of Xist expression, the proportion of which changed over time. At E6.5, 1. a small fraction of the cells showed low level biallelic Xist expression. 2. a slightly larger proportion of cells displayed differential biallelic Xist expression. 3. in the majority of cells, abundant Xist RNA was detected from only one locus.
Specimen Label: Female E6.5
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1097413
Assay Type: RNA in situ
Annotation Date: 2022-08-24
Strength: Present
Sex: Female
Emaps: EMAPS:1603910
Pattern: Regionally restricted
Stage: TS10
Assay Id: MGI:7331495
Age: embryonic day 7.0
Note: Female embryos showed three patterns of Xist expression, the proportion of which changed over time. At E7.0, 1. a small fraction of the cells showed low level biallelic Xist expression. 2. a slightly larger proportion of cells displayed differential biallelic Xist expression. 3. in the majority of cells, abundant Xist RNA was detected from only one locus.
Specimen Label: Female E7.0
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6459731
Assay Type: RNA in situ
Annotation Date: 2020-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160508
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:6459735
Age: embryonic day 5.25
Image: 1f
Note: More than half of the cells (55%) had Xist signals with most of the cells showing dispersed Xist signals. Cells with Xist clouds began to appear. Shown is a single cell with one Xist dispersed signal and a single Tsix spot.
Specimen Label: 1f
Detected: true
Specimen Num: 4
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Publication
7849742 | J:20704
 
First Author: Heard E
Year: 1994
Journal: Hum Mol Genet
Title: Role play in X-inactivation.
Volume: 3 Spec No
Pages: 1481-5
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Publication
21118898 | J:168715
First Author: Chureau C
Year: 2011
Journal: Hum Mol Genet
Title: Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region.
Volume: 20
Issue: 4
Pages: 705-18
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•
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Publication
8789438 | J:30901
First Author: Rougeulle C
Year: 1996
Journal: Hum Mol Genet
Title: Cloning and characterization of a murine brain specific gene Bpx and its human homologue lying within the Xic candidate region.
Volume: 5
Issue: 1
Pages: 41-9
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•
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Publication
8460399 | J:4324
First Author: Salido EC
Year: 1993
Journal: Somat Cell Mol Genet
Title: An evaluation of the inactive mouse X chromosome in somatic cell hybrids.
Volume: 19
Issue: 1
Pages: 65-71
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•
•
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Publication
9115428 | J:39951
First Author: Lee JT
Year: 1997
Journal: Curr Opin Genet Dev
Title: The (epi)genetic control of mammalian X-chromosome inactivation.
Volume: 7
Issue: 2
Pages: 274-80
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•
•
•
Publication
30033120 | J:271498
First Author: Matoba S
Year: 2018
Journal: Cell Stem Cell
Title: Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development.
Volume: 23
Issue: 3
Pages: 343-354.e5
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•
•
•
•
Publication
38458200 | J:346696
     
First Author: Wei C
Year: 2024
Journal: Mol Cell
Title: Imprinted X chromosome inactivation at the gamete-to-embryo transition.
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•
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Publication
30463900 | J:272571
First Author: Inoue A
Year: 2018
Journal: Genes Dev
Title: Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells.
Volume: 32
Issue: 23-24
Pages: 1525-1536
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•
•
•
•
Publication
17676999 | J:123745
First Author: Sugimoto M
Year: 2007
Journal: PLoS Genet
Title: X chromosome reactivation initiates in nascent primordial germ cells in mice.
Volume: 3
Issue: 7
Pages: e116
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•
•
•
Publication
10640679 | J:59177
First Author: Eriksson A
Year: 1999
Journal: Brain Res Mol Brain Res
Title: Isolation of sex-specific cDNAs from fetal mouse brain using mRNA differential display and representational difference analysis.
Volume: 74
Issue: 1-2
Pages: 91-7
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•
•
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Publication
8118102 | J:14461
First Author: Simmler MC
Year: 1993
Journal: Mamm Genome
Title: Mapping the murine Xce locus with (CA)n repeats.
Volume: 4
Issue: 9
Pages: 523-30
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•
•
•
•
Publication
11287190 | J:69276
First Author: Davis RJ
Year: 2001
Journal: Mech Dev
Title: Characterization of mouse Dach2, a homologue of Drosophila dachshund.
Volume: 102
Issue: 1-2
Pages: 169-79
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•
•
•
Publication
30970248 | J:276965
First Author: Delbridge ARD
Year: 2019
Journal: Cell Rep
Title: Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.
Volume: 27
Issue: 2
Pages: 442-454.e5
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•
•
•
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Publication
35148843 | J:326514
First Author: Mira-Bontenbal H
Year: 2022
Journal: Stem Cell Reports
Title: Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells.
Volume: 17
Issue: 3
Pages: 693-706
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Publication
29282321 | J:260593
First Author: Carrette LLG
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders.
Volume: 115
Issue: 4
Pages: E668-E675
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Publication
30938678 | J:275851
   
First Author: Harris C
Year: 2019
Journal: Elife
Title: Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2.
Volume: 8
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•
•
•
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Publication
28134930 | J:320748
First Author: Borensztein M
Year: 2017
Journal: Nat Struct Mol Biol
Title: Xist-dependent imprinted X inactivation and the early developmental consequences of its failure.
Volume: 24
Issue: 3
Pages: 226-233
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Publication
28684628 | J:243417
First Author: Sakata Y
Year: 2017
Journal: Development
Title: Defects in dosage compensation impact global gene regulation in the mouse trophoblast.
Volume: 144
Issue: 15
Pages: 2784-2797
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•
•
•
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Publication
2034278 | J:11179
First Author: Borsani G
Year: 1991
Journal: Nature
Title: Characterization of a murine gene expressed from the inactive X chromosome.
Volume: 351
Issue: 6324
Pages: 325-9
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•
•
•
•
Publication
8845836 | J:32256
First Author: Heard E
Year: 1996
Journal: Hum Mol Genet
Title: Transgenic mice carrying an Xist-containing YAC.
Volume: 5
Issue: 4
Pages: 441-50
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•
•
•
•
Publication
8689690 | J:34201
First Author: Lee JT
Year: 1996
Journal: Cell
Title: A 450 kb transgene displays properties of the mammalian X-inactivation center.
Volume: 86
Issue: 1
Pages: 83-94
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•
•
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Publication
8844160 | J:34507
First Author: Montagutelli X
Year: 1996
Journal: Genetics
Title: Epistatic control of non-Mendelian inheritance in mouse interspecific crosses.
Volume: 143
Issue: 4
Pages: 1739-52
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•
•
•
•
Publication
15733677 | J:96532
First Author: Nolen LD
Year: 2005
Journal: Dev Biol
Title: X chromosome reactivation and regulation in cloned embryos.
Volume: 279
Issue: 2
Pages: 525-40
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•
•
•
•
Publication
29804891 | J:316300
First Author: Sousa EJ
Year: 2018
Journal: Cell Stem Cell
Title: Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males.
Volume: 22
Issue: 6
Pages: 919-928.e6
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•
•
•
•
Publication
30625149 | J:270292
First Author: Symmons O
Year: 2019
Journal: PLoS Genet
Title: Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting.
Volume: 15
Issue: 1
Pages: e1007874
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•
•
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Publication
18535243 | J:136422
First Author: Ogawa Y
Year: 2008
Journal: Science
Title: Intersection of the RNA interference and X-inactivation pathways.
Volume: 320
Issue: 5881
Pages: 1336-41
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•
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Publication
12434336 | J:80693
First Author: McCarrey JR
Year: 2002
Journal: Genesis
Title: X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse.
Volume: 34
Issue: 4
Pages: 257-66
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•
•
•
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Publication
18974356 | J:140631
First Author: Zhao J
Year: 2008
Journal: Science
Title: Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.
Volume: 322
Issue: 5902
Pages: 750-6
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•
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Publication
24144980 | J:206754
First Author: Escamilla-Del-Arenal M
Year: 2013
Journal: Mol Cell Biol
Title: Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.
Volume: 33
Issue: 24
Pages: 5005-20
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Publication
12356914 | J:80117
First Author: Turner JM
Year: 2002
Journal: J Cell Sci
Title: Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.
Volume: 115
Issue: Pt 21
Pages: 4097-105
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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