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Search results 101 to 190 out of 190 for Zbp1

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Type Details Score
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-MTAB-11540 | RNA-sequencing of lung RNA from mice with compound mutations in ADAR1 and MAVS, ZBP1 or RIPK3.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE254754 | ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-MTAB-10953 | RNA-sequencing of splenic RNA from mice with compound mutations in ADAR1 and ZBP1
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-MTAB-11537 | RNA-sequencing of brain RNA from mice with compound mutations in ADAR1 and MAVS or ZBP1
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Pathway
R-MMU-1810476 | RIP-mediated NFkB activation via ZBP1
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Publication
29321274 | J:258250
First Author: Kuriakose T
Year: 2018
Journal: J Immunol
Title: IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection.
Volume: 200
Issue: 4
Pages: 1489-1495
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Publication
20080952 | -
First Author: Chao JA
Year: 2010
Journal: Genes Dev
Title: ZBP1 recognition of beta-actin zipcode induces RNA looping.
Volume: 24
Issue: 2
Pages: 148-58
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Publication
17893325 | -
First Author: Pan F
Year: 2007
Journal: Mol Cell Biol
Title: ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription.
Volume: 27
Issue: 23
Pages: 8340-51
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HT Experiment
GSE200854 | ADAR1 mutation causes ZBP1-dependent immunopathology
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Coding Gene
MGI:1890357 | Igf2bp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108177 | Dhx9
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O70133
Organism: Mus musculus/domesticus
Length: 1380  
Fragment?: false
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Protein Coding Gene
MGI:108005 | Myd88
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P22366
Organism: Mus musculus/domesticus
Length: 296  
Fragment?: false
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Protein Coding Gene
MGI:1919216 | Nkiras2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916971 | Nkiras1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CR56
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
Q8CEC5
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Publication
36604592 | J:355686
First Author: Lee SA
Year: 2023
Journal: Nat Cell Biol
Title: OASL phase condensation induces amyloid-like fibrillation of RIPK3 to promote virus-induced necroptosis.
Volume: 25
Issue: 1
Pages: 92-107
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Publication
23100434 | J:192172
First Author: Nalavadi VC
Year: 2012
Journal: J Neurosci
Title: Regulation of zipcode binding protein 1 transport dynamics in axons by myosin Va.
Volume: 32
Issue: 43
Pages: 15133-41
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Publication
31287416 | J:277691
   
First Author: Lim J
Year: 2019
Journal: Elife
Title: Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.
Volume: 8
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Publication
32362323 | J:306381
First Author: Schwarzer R
Year: 2020
Journal: Immunity
Title: FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells.
Volume: 52
Issue: 6
Pages: 978-993.e6
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Publication
35511979 | J:324236
First Author: Yuan F
Year: 2022
Journal: Science
Title: Z-DNA binding protein 1 promotes heatstroke-induced cell death.
Volume: 376
Issue: 6593
Pages: 609-615
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Protein Coding Gene
MGI:1099800 | Nfkb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104752 | Nfkbib
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q60778
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
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Protein
Q9WTK5
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Publication
10535945 | -
First Author: Schade M
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA.
Volume: 96
Issue: 22
Pages: 12465-70
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Publication
8716805 | -
First Author: Sharma T
Year: 1996
Journal: J Psychiatr Ment Health Nurs
Title: The idea of partnership is fine, but what about perceptions?
Volume: 3
Issue: 2
Pages: 133-4
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Publication
27265117 | -
First Author: Subramani VK
Year: 2016
Journal: FEBS Lett
Title: Structural and functional studies of a large winged Z-DNA-binding domain of Danio rerio protein kinase PKZ.
Volume: 590
Issue: 14
Pages: 2275-85
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Publication
30592616 | -
First Author: Lee AR
Year: 2019
Journal: ACS Chem Biol
Title: NMR Dynamics Study Reveals the Zα Domain of Human ADAR1 Associates with and Dissociates from Z-RNA More Slowly than Z-DNA.
Volume: 14
Issue: 2
Pages: 245-255
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Protein Domain
IPR042371 | Z_dom
Type: Domain
Description: Double-stranded (ds) DNA typically adopts the so-called B-conformation, while dsRNA is usually in the A-conformation. Both DNA and RNA can also adopt a Z-form double helix that is characterised by a left-handed helical arrangement, a zigzag pattern of the phosphodiester backbone and the absence of major grooves. Z-DNA is believed to play a role in transcription by relieving torsional strain induced within the DNA template by the movement of RNA polymerases, and Z-DNA may also promote genetic instability. Physiological functions of Z-RNA remain unknown. This entry represents the Z-binding domain (ZBD), also referred to as Zalpha or Zbeta, which is a 78-amino-acid protein fold that specifically binds to Z-DNA as well as to Z-RNA but not to B-DNA. ZBDs have been identified in four proteins: ADAR1, ZBP1, E3L and PKZ. ADAR1 and ZBP1 are mammalian proteins implicated in antiviral innate immune responses. E3L is a poxvirus protein known to antagonise this host response. Lastly, PKZ is a fish protein related to mammalian PKR, also involved in antiviral immunity. This suggests an important role of ZBDs in innate antiviral immune responses and may imply that Z-DNA and/or Z-RNA trigger such a host defense response [, , , , , ].The Z-binding domain displays an α/β architecture with three α-helices packed against three antiparallel β-strands (). It belongs to the winged helix-turn-helix (wHTH) domain superfamily. The three helices form the core of the domain, with helices 2 and 3 forming the helix-turn-helix unit. Helix 1is joined to helix 2 by a β-strand, beta1. C-terminal to helix 3 is the 'wing', formed by two antiparallel β-strands (β2 and β3), which hydrogen bond to each other and to beta1, forming a three-stranded β-sheet [, ].
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Publication
38200309 | J:349030
First Author: Cho MG
Year: 2024
Journal: Nature
Title: MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Volume: 625
Issue: 7995
Pages: 585-592
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Publication
34462571 | J:335390
First Author: Moriwaki K
Year: 2022
Journal: Mucosal Immunol
Title: The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis.
Volume: 15
Issue: 1
Pages: 84-95
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Publication
21734271 | J:174562
First Author: Welshhans K
Year: 2011
Journal: J Neurosci
Title: Netrin-1-induced local β-actin synthesis and growth cone guidance requires zipcode binding protein 1.
Volume: 31
Issue: 27
Pages: 9800-13
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Publication
27270670 | J:249539
First Author: Baj G
Year: 2016
Journal: J Cell Sci
Title: Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors.
Volume: 129
Issue: 14
Pages: 2852-64
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Publication
37454215 | J:338314
First Author: Du J
Year: 2023
Journal: Cell Death Dis
Title: PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation.
Volume: 14
Issue: 7
Pages: 432
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Publication
39215356 | J:353898
First Author: Joshi R
Year: 2024
Journal: J Neuroinflammation
Title: IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
Volume: 21
Issue: 1
Pages: 212
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Publication
22215810 | J:179370
First Author: Patel VL
Year: 2012
Journal: Genes Dev
Title: Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.
Volume: 26
Issue: 1
Pages: 43-53
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Publication
29343810 | J:260215
First Author: Szczesny B
Year: 2018
Journal: Sci Rep
Title: Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells.
Volume: 8
Issue: 1
Pages: 914
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Publication
32296174 | J:289213
First Author: Wang R
Year: 2020
Journal: Nature
Title: Gut stem cell necroptosis by genome instability triggers bowel inflammation.
Volume: 580
Issue: 7803
Pages: 386-390
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Publication
32111743 | J:300635
First Author: Wu H
Year: 2020
Journal: J Biol Chem
Title: A kinesin adapter directly mediates dendritic mRNA localization during neural development in mice.
Volume: 295
Issue: 19
Pages: 6605-6628
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Publication
38850531 | J:360956
First Author: Rodriguez DA
Year: 2024
Journal: Cell Rep
Title: The interaction between RIPK1 and FADD controls perinatal lethality and inflammation.
Volume: 43
Issue: 6
Pages: 114335
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Protein Coding Gene
MGI:104741 | Nfkbia
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103290 | Rela
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99484 | Chuk
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97312 | Nfkb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1338071 | Ikbkb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88351
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: false
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Protein
Q9Z1E3
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
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Protein
Q60680
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein
Q04207
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
P25799
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Publication
28073938 | J:239294
First Author: Lepelletier L
Year: 2017
Journal: J Neurosci
Title: Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation.
Volume: 37
Issue: 7
Pages: 1685-1695
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Protein Coding Gene
MGI:1338074 | Ikbkg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88522
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
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Publication
35338116 | J:322882
First Author: Messaoud-Nacer Y
Year: 2022
Journal: Cell Death Dis
Title: STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS).
Volume: 13
Issue: 3
Pages: 269
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Protein
A2IBT3
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
Q99MU3
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
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Protein
Q5J4D4
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
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Protein
Q3UH31
Organism: Mus musculus/domesticus
Length: 930  
Fragment?: false
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Protein
Q5J4D5
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: true
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Protein
Q4FJS9
Organism: Mus musculus/domesticus
Length: 1152  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom