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Search results 101 to 186 out of 186 for Zc3h12a

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1F
Specimen Label: 1F
Detected: true
Specimen Num: 9
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Publication
36470473 | J:332638
     
First Author: Morisaka H
Year: 2022
Journal: J Invest Dermatol
Title: Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
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Publication
36165203 | J:360025
First Author: Wadowska M
Year: 2022
Journal: J Immunol
Title: MCP-Induced Protein 1 Participates in Macrophage-Dependent Endotoxin Tolerance.
Volume: 209
Issue: 7
Pages: 1348-1358
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Publication
35159206 | J:325883
 
First Author: Ribeiro A
Year: 2022
Journal: Cells
Title: Macrophage-Specific MCPIP1/Regnase-1 Attenuates Kidney Ischemia-Reperfusion Injury by Shaping the Local Inflammatory Response and Tissue Regeneration.
Volume: 11
Issue: 3
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Publication
34058074 | J:329414
First Author: Pydyn N
Year: 2021
Journal: FEBS J
Title: Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts.
Volume: 288
Issue: 22
Pages: 6563-6580
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Publication
39032853 | J:358934
First Author: Szukala W
Year: 2024
Journal: Biochim Biophys Acta Gen Subj
Title: Keratinocyte and myeloid MCPIP1 have distinct roles in maintaining skin homeostasis.
Volume: 1868
Issue: 10
Pages: 130671
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Publication
29263935 | J:255787
 
First Author: Li Y
Year: 2017
Journal: Signal Transduct Target Ther
Title: Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury.
Volume: 2
Pages: 17066
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Publication
29127149 | J:252603
First Author: Cui X
Year: 2017
Journal: J Immunol
Title: Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis.
Volume: 199
Issue: 12
Pages: 4066-4077
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Publication
30842549 | J:276884
First Author: Kidoya H
Year: 2019
Journal: Nat Commun
Title: Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis.
Volume: 10
Issue: 1
Pages: 1072
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Publication
34298932 | J:309002
 
First Author: Wawro M
Year: 2021
Journal: Int J Mol Sci
Title: Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology.
Volume: 22
Issue: 14
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Publication
34135341 | J:347369
First Author: Tomita T
Year: 2021
Journal: Nat Commun
Title: Extracellular mRNA transported to the nucleus exerts translation-independent function.
Volume: 12
Issue: 1
Pages: 3655
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Publication
34636324 | J:316931
   
First Author: Akaki K
Year: 2021
Journal: Elife
Title: IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay.
Volume: 10
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Publication
26255671 | J:229326
First Author: Mino T
Year: 2015
Journal: Oncotarget
Title: Regnase-1 and Roquin regulate inflammatory mRNAs.
Volume: 6
Issue: 20
Pages: 17869-70
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Publication
34236049 | J:313003
 
First Author: Li DD
Year: 2021
Journal: JCI Insight
Title: RTEC-intrinsic IL-17-driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1.
Volume: 6
Issue: 13
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Publication
24223214 | J:209217
First Author: Yu F
Year: 2013
Journal: PLoS One
Title: Bone marrow deficiency of MCPIP1 results in severe multi-organ inflammation but diminishes atherogenesis in hyperlipidemic mice.
Volume: 8
Issue: 11
Pages: e80089
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Publication
31185306 | J:278358
First Author: Pydyn N
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: RNase MCPIP1 regulates hepatic peroxisome proliferator-activated receptor gamma via TXNIP/PGC-1alpha pathway.
Volume: 1864
Issue: 10
Pages: 1458-1471
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Publication
31931613 | J:302310
First Author: Omiya S
Year: 2020
Journal: Circulation
Title: Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts.
Volume: 141
Issue: 8
Pages: 667-677
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Publication
37814340 | J:358043
First Author: Okabe J
Year: 2023
Journal: J Exp Clin Cancer Res
Title: Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity.
Volume: 42
Issue: 1
Pages: 262
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Publication
30297433 | J:266525
First Author: Nagahama Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolism.
Volume: 115
Issue: 43
Pages: 11036-11041
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Publication
20561987 | J:162083
First Author: Qi Y
Year: 2010
Journal: FEBS Lett
Title: MCP-induced protein 1 suppresses TNFalpha-induced VCAM-1 expression in human endothelial cells.
Volume: 584
Issue: 14
Pages: 3065-72
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Publication
31155290 | J:291139
First Author: Shu S
Year: 2019
Journal: Biochem Biophys Res Commun
Title: The role of monocyte chemotactic protein-induced protein 1 (MCPIP1) in angiotensin II-induced macrophage apoptosis and vulnerable plaque formation.
Volume: 515
Issue: 2
Pages: 378-385
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Publication
29742804 | J:288150
First Author: Sun P
Year: 2018
Journal: Hepatology
Title: Monocyte Chemoattractant Protein-Induced Protein 1 Targets Hypoxia-Inducible Factor 1α to Protect Against Hepatic Ischemia/Reperfusion Injury.
Volume: 68
Issue: 6
Pages: 2359-2375
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Publication
29339122 | J:333037
First Author: Takaishi M
Year: 2018
Journal: J Invest Dermatol
Title: Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation.
Volume: 138
Issue: 6
Pages: 1439-1442
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Publication
27920272 | J:247740
First Author: Monin L
Year: 2017
Journal: J Immunol
Title: MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation.
Volume: 198
Issue: 2
Pages: 767-775
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Publication
31990689 | J:288755
 
First Author: Matsushita K
Year: 2020
Journal: JCI Insight
Title: Regnase-1 degradation is crucial for IL-33- and IL-25-mediated ILC2 activation.
Volume: 5
Issue: 4
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Publication
28538180 | J:254708
First Author: Yoshinaga M
Year: 2017
Journal: Cell Rep
Title: Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs.
Volume: 19
Issue: 8
Pages: 1614-1630
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Publication
30962593 | J:282323
First Author: Majumder S
Year: 2019
Journal: Nat Immunol
Title: IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.
Volume: 20
Issue: 5
Pages: 534-545
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Publication
34811541 | J:324878
First Author: Behrens G
Year: 2021
Journal: Nat Immunol
Title: Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
Volume: 22
Issue: 12
Pages: 1563-1576
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Publication
34471108 | J:310403
First Author: Hoefig KP
Year: 2021
Journal: Nat Commun
Title: Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Volume: 12
Issue: 1
Pages: 5208
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Publication
24270572 | J:206842
First Author: Niu J
Year: 2013
Journal: EMBO J
Title: USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO.
Volume: 32
Issue: 24
Pages: 3206-19
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Publication
27523618 | J:310876
First Author: Jiang H
Year: 2016
Journal: Stem Cell Reports
Title: Immune Regulator MCPIP1 Modulates TET Expression during Early Neocortical Development.
Volume: 7
Issue: 3
Pages: 439-453
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q5D1E7
Organism: Mus musculus/domesticus
Length: 596  
Fragment?: false
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Allele
Tg(Myh6-Zc3h12a)#Pako | MGI:6429873
Name: transgene insertion, Pappachan Kolattukudy
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein
Q80U38
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
Q99KT2
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
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Protein
Q5EBQ4
Organism: Mus musculus/domesticus
Length: 694  
Fragment?: true
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Protein
A2BE29
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
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Publication
31133753 | -
First Author: Yamasoba D
Year: 2019
Journal: Nat Microbiol
Title: N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.
Volume: 4
Issue: 9
Pages: 1532-1544
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Protein Domain
IPR021869 | RNase_Zc3h12_NYN
Type: Domain
Description: This domain is found in the Zc3h12a protein and NEDD4-binding protein 1. Zc3h12a has been shown to be a ribonuclease that controls the stability of a set of inflammatory genes []. NEDD4-binding protein 1 is a potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation []. This domain belongs to the PIN domain superfamily []and it has also been identified as part of the NYN domain family [].
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Publication
29244194 | J:261340
First Author: Hanieh H
Year: 2018
Journal: Eur J Immunol
Title: Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3'UTR.
Volume: 48
Issue: 4
Pages: 593-604
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Protein
Q3UYJ7
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Publication
31126966 | J:277714
First Author: von Gamm M
Year: 2019
Journal: J Exp Med
Title: Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
Volume: 216
Issue: 7
Pages: 1700-1723
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Protein
Q6A037
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Protein
A0A2I3BPI4
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
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Publication
17114934 | -
First Author: Anantharaman V
Year: 2006
Journal: RNA Biol
Title: The NYN domains: novel predicted RNAses with a PIN domain-like fold.
Volume: 3
Issue: 1
Pages: 18-27
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Publication
32218530 | J:298375
First Author: Jiang R
Year: 2020
Journal: Lab Invest
Title: Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
Volume: 100
Issue: 7
Pages: 959-973
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Protein
Q5DTV4
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
Q8BIY3
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: false
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Protein
E9Q1I3
Organism: Mus musculus/domesticus
Length: 903  
Fragment?: false
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Protein
E9QNR7
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: false
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Protein
G3X9I7
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
Q5DTZ0
Organism: Mus musculus/domesticus
Length: 1840  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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