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Search results 101 to 186 out of 186 for Zfp36l2

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Small Intestine
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Large Intestine
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Pancreas
Detected: true
Specimen Num: 14
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•
GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Salivary
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Fat
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Eye
Detected: true
Specimen Num: 18
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•
GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Uterus
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Mammary
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6414587
Age: embryonic day 14.5
Specimen Label: Fetal Liver
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:6414587
Age: postnatal adult
Specimen Label: Bone Marrow
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608526
Stage: TS26
Assay Id: MGI:6414586
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6414576
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6414586
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
     
Probe: MGI:7435566
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435598
Age: postnatal month 2
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7435566
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435598
Age: postnatal month 2
Specimen Label: Nrl<-/->
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6414577
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6414591
Age: postnatal adult
Specimen Label: 3A KO mother
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5502904
Assay Type: RNA in situ
Annotation Date: 2013-08-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5502905
Age: embryonic day 13.5
Note: Expression was detected in dorsal telencephalon.
Specimen Label: Supp. Table 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414577
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6414591
Age: embryonic day 14.5
Specimen Label: 3A WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6414577
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6414591
Age: embryonic day 14.5
Specimen Label: 3A KO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6414577
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6414591
Age: embryonic day 14.5
Note: Expression is in many tissues.
Specimen Label: 3A WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414577
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1684622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6414591
Age: embryonic day 14.5
Specimen Label: 3A WT
Detected: true
Specimen Num: 1
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Publication
29988089 | J:282498
First Author: Salerno F
Year: 2018
Journal: Nat Immunol
Title: Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.
Volume: 19
Issue: 8
Pages: 828-837
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Publication
15814898 | J:100670
First Author: Blackshear PJ
Year: 2005
Journal: Biol Reprod
Title: Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.
Volume: 73
Issue: 2
Pages: 297-307
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Publication
18682727 | J:140125
First Author: Liang J
Year: 2008
Journal: PLoS One
Title: Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.
Volume: 3
Issue: 8
Pages: e2880
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Publication
28394372 | J:259588
First Author: Newman R
Year: 2017
Journal: Nat Immunol
Title: Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.
Volume: 18
Issue: 6
Pages: 683-693
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Publication
38157296 | J:352778
First Author: Sunshine HL
Year: 2024
Journal: Cell Rep
Title: Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins.
Volume: 43
Issue: 1
Pages: 113627
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Publication
12082611 | J:77717
First Author: Johnson BA
Year: 2002
Journal: Oncogene
Title: Multiple tristetraprolin sequence domains required to induce apoptosis and modulate responses to TNFalpha through distinct pathways.
Volume: 21
Issue: 27
Pages: 4237-46
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Publication
26952984 | J:230794
First Author: Stumpo DJ
Year: 2016
Journal: Development
Title: Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.
Volume: 143
Issue: 8
Pages: 1424-33
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Publication
15467755 | J:94140
First Author: Ciais D
Year: 2004
Journal: Oncogene
Title: Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b.
Volume: 23
Issue: 53
Pages: 8673-80
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Publication
31330130 | J:282329
First Author: Hildebrandt MR
Year: 2019
Journal: Dev Biol
Title: Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.
Volume: 455
Issue: 2
Pages: 420-433
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Publication
15163632 | J:225638
First Author: Yoshida S
Year: 2004
Journal: Hum Mol Genet
Title: Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
Volume: 13
Issue: 14
Pages: 1487-503
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Publication
15328020 | J:93141
First Author: Mattar P
Year: 2004
Journal: Dev Biol
Title: A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.
Volume: 273
Issue: 2
Pages: 373-89
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: mRNA decay activator protein ZFP36L2
Type: chain
End: 484
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HT Experiment
GSE158718 | Roles of Zfp36l1 and Zfp36l2 in retinal development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE15146 | mRNA expression in Zfp36L2 knockout E14.5 fetal liver
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Protein
P23949
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
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HT Experiment
GSE79174 | RNAseq of pre-T cells from control and Zfp36l1, Zfp36l2 double conditional knockout mice.
Series Id: E-GEOD-79174
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE96638 | Single-cell RNA sequencing of Zfp36l2 knock-out and floxed GV mouse oocytes.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
29449217 | -
 
First Author: Noguchi A
Year: 2018
Journal: Biol Open
Title: ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.
Volume: 7
Issue: 3
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Publication
25106868 | -
First Author: Adachi S
Year: 2014
Journal: Nucleic Acids Res
Title: ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Volume: 42
Issue: 15
Pages: 10037-49
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Publication
23046558 | -
First Author: Farina NH
Year: 2012
Journal: Skelet Muscle
Title: A role for RNA post-transcriptional regulation in satellite cell activation.
Volume: 2
Issue: 1
Pages: 21
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Publication
25815583 | J:244789
 
First Author: Hausburg MA
Year: 2015
Journal: Elife
Title: Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay.
Volume: 4
Pages: e03390
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Publication
27810909 | -
First Author: Balachandran RS
Year: 2016
Journal: J Cell Biol
Title: The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.
Volume: 215
Issue: 2
Pages: 151-166
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Publication
31273098 | -
 
First Author: Timms RT
Year: 2019
Journal: Science
Title: A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.
Volume: 365
Issue: 6448
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Protein Domain
IPR040367 | ZYG11B
Type: Family
Description: This entry includes protein zyg-11 homologue B from vertebrates. In Caenorhabditis elegans, Zyg-11 (not included in this entry) is the substrate-recognition subunit for a CUL-2-based complex that regulates several key processes in cell division and embryonic development []. Similarly, the CRL2-ZYG11 complex in humans acts as a ubiquitin ligase and is comprised of the cullin CUL2, the RING finger protein Rbx1/Roc1, the adaptor subunit Elongin C, and ZYG-11 orthologues ZYG11A or ZYG11B. In human cells, the CRL2ZYG11A/B-mediated degradation of cyclin B1 facilitates mitotic slippage in cells in which APC/C is inactive []. The ZYG11B-based E3 ubiquitin ligase complex mediates polyubiquitination of the cell cycle-regulated protein ZFP36L2 []. ZYG11B targets substrates bearing N-terminal glycine degrons for proteasomal degradation and it is also involved in the quality control of protein N-myristoylation in which N-terminal glycine degrons are exposed after a failure of N-myristoylation [].
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Publication
20166898 | J:234003
First Author: Hacker C
Year: 2010
Journal: Growth Factors
Title: ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.
Volume: 28
Issue: 3
Pages: 178-90
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Publication
17304241 | -
First Author: Vasudevan S
Year: 2007
Journal: EMBO Rep
Title: The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.
Volume: 8
Issue: 3
Pages: 279-86
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Publication
18367448 | J:137576
First Author: Frederick ED
Year: 2008
Journal: J Biol Chem
Title: A unique C-terminal repeat domain maintains the cytosolic localization of the placenta-specific tristetraprolin family member ZFP36L3.
Volume: 283
Issue: 21
Pages: 14792-800
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Publication
34815797 | J:314951
First Author: Chuang HC
Year: 2021
Journal: Theranostics
Title: BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus.
Volume: 11
Issue: 20
Pages: 9953-9966
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Publication
22956911 | J:188119
First Author: Lee JE
Year: 2012
Journal: PLoS Genet
Title: The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts.
Volume: 8
Issue: 8
Pages: e1002901
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Publication
23904106 | J:240792
First Author: Lai WS
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Life without TTP: apparent absence of an important anti-inflammatory protein in birds.
Volume: 305
Issue: 7
Pages: R689-700
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Publication
32868912 | J:331299
First Author: Wang F
Year: 2021
Journal: Cell Mol Immunol
Title: Exploring the stage-specific roles of Tcf-1 in T cell development and malignancy at single-cell resolution.
Volume: 18
Issue: 3
Pages: 644-659
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Protein
Q3UFS0
Organism: Mus musculus/domesticus
Length: 744  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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